Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KRAS.KIDNEY_UP.V1_UP |
| Enrichment Score (ES) | -0.6315675 |
| Normalized Enrichment Score (NES) | -1.3790319 |
| Nominal p-value | 0.006857143 |
| FDR q-value | 0.26125106 |
| FWER p-Value | 0.694 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PLCL1 | phospholipase C like 1 (inactive) [Source:HGNC Symbol;Acc:HGNC:9063] | 508 | 2.938 | 0.0282 | No |
| 2 | CRTAM | cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:HGNC:24313] | 837 | 2.353 | 0.0529 | No |
| 3 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 1984 | 1.367 | 0.0414 | No |
| 4 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16789] | 2036 | 1.332 | 0.0591 | No |
| 5 | DDX6 | DEAD-box helicase 6 [Source:HGNC Symbol;Acc:HGNC:2747] | 2082 | 1.302 | 0.0765 | No |
| 6 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626] | 2661 | 1.061 | 0.0760 | No |
| 7 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 3384 | 0.781 | 0.0676 | No |
| 8 | RNLS | renalase, FAD dependent amine oxidase [Source:HGNC Symbol;Acc:HGNC:25641] | 3682 | 0.682 | 0.0693 | No |
| 9 | CAB39L | calcium binding protein 39 like [Source:HGNC Symbol;Acc:HGNC:20290] | 3872 | 0.615 | 0.0730 | No |
| 10 | GLDC | glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313] | 4635 | 0.396 | 0.0580 | No |
| 11 | CP | ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295] | 4748 | 0.360 | 0.0601 | No |
| 12 | SCN1B | sodium voltage-gated channel beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:10586] | 5205 | 0.239 | 0.0512 | No |
| 13 | ADCY1 | adenylate cyclase 1 [Source:HGNC Symbol;Acc:HGNC:232] | 6101 | 0.069 | 0.0279 | No |
| 14 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6577 | 0.000 | 0.0151 | No |
| 15 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6579 | 0.000 | 0.0150 | No |
| 16 | WSCD1 | WSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29060] | 6596 | 0.000 | 0.0146 | No |
| 17 | CRYAB | crystallin alpha B [Source:HGNC Symbol;Acc:HGNC:2389] | 6709 | 0.000 | 0.0116 | No |
| 18 | DYNC1I1 | dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963] | 6930 | 0.000 | 0.0056 | No |
| 19 | AQP4 | aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637] | 7126 | 0.000 | 0.0004 | No |
| 20 | NRXN1 | neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008] | 7259 | 0.000 | -0.0032 | No |
| 21 | HPCAL4 | hippocalcin like 4 [Source:HGNC Symbol;Acc:HGNC:18212] | 7311 | 0.000 | -0.0046 | No |
| 22 | HEY1 | hes related family bHLH transcription factor with YRPW motif 1 [Source:HGNC Symbol;Acc:HGNC:4880] | 7369 | 0.000 | -0.0061 | No |
| 23 | GPRC5B | G protein-coupled receptor class C group 5 member B [Source:HGNC Symbol;Acc:HGNC:13308] | 7379 | 0.000 | -0.0064 | No |
| 24 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7861 | 0.000 | -0.0194 | No |
| 25 | MPZL2 | myelin protein zero like 2 [Source:HGNC Symbol;Acc:HGNC:3496] | 7974 | 0.000 | -0.0224 | No |
| 26 | EPB41L3 | erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380] | 8101 | 0.000 | -0.0258 | No |
| 27 | PCDH9 | protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661] | 8204 | 0.000 | -0.0286 | No |
| 28 | PELI2 | pellino E3 ubiquitin protein ligase family member 2 [Source:HGNC Symbol;Acc:HGNC:8828] | 8621 | 0.000 | -0.0399 | No |
| 29 | CALB1 | calbindin 1 [Source:HGNC Symbol;Acc:HGNC:1434] | 8884 | 0.000 | -0.0469 | No |
| 30 | SMR3A | submaxillary gland androgen regulated protein 3A [Source:HGNC Symbol;Acc:HGNC:19216] | 9004 | 0.000 | -0.0502 | No |
| 31 | PLSCR4 | phospholipid scramblase 4 [Source:HGNC Symbol;Acc:HGNC:16497] | 9315 | 0.000 | -0.0586 | No |
| 32 | GRIA2 | glutamate ionotropic receptor AMPA type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4572] | 9344 | 0.000 | -0.0593 | No |
| 33 | CDR1 | cerebellar degeneration related protein 1 [Source:HGNC Symbol;Acc:HGNC:1798] | 9558 | 0.000 | -0.0651 | No |
| 34 | NEBL | nebulette [Source:HGNC Symbol;Acc:HGNC:16932] | 9704 | 0.000 | -0.0690 | No |
| 35 | NEFL | neurofilament light [Source:HGNC Symbol;Acc:HGNC:7739] | 9722 | 0.000 | -0.0695 | No |
| 36 | KCNA5 | potassium voltage-gated channel subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:6224] | 9756 | 0.000 | -0.0704 | No |
| 37 | KCNJ8 | potassium inwardly rectifying channel subfamily J member 8 [Source:HGNC Symbol;Acc:HGNC:6269] | 9881 | 0.000 | -0.0737 | No |
| 38 | LIMCH1 | LIM and calponin homology domains 1 [Source:HGNC Symbol;Acc:HGNC:29191] | 9900 | 0.000 | -0.0742 | No |
| 39 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 10013 | 0.000 | -0.0772 | No |
| 40 | PMP2 | peripheral myelin protein 2 [Source:HGNC Symbol;Acc:HGNC:9117] | 10424 | 0.000 | -0.0883 | No |
| 41 | RTN1 | reticulon 1 [Source:HGNC Symbol;Acc:HGNC:10467] | 10565 | 0.000 | -0.0921 | No |
| 42 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10616 | 0.000 | -0.0935 | No |
| 43 | CHGB | chromogranin B [Source:HGNC Symbol;Acc:HGNC:1930] | 10637 | 0.000 | -0.0940 | No |
| 44 | SPARCL1 | SPARC like 1 [Source:HGNC Symbol;Acc:HGNC:11220] | 11443 | 0.000 | -0.1158 | No |
| 45 | ERC2 | ELKS/RAB6-interacting/CAST family member 2 [Source:HGNC Symbol;Acc:HGNC:31922] | 11570 | 0.000 | -0.1192 | No |
| 46 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 11960 | 0.000 | -0.1297 | No |
| 47 | SIGLEC15 | sialic acid binding Ig like lectin 15 [Source:HGNC Symbol;Acc:HGNC:27596] | 11992 | 0.000 | -0.1306 | No |
| 48 | NME5 | NME/NM23 family member 5 [Source:HGNC Symbol;Acc:HGNC:7853] | 12023 | 0.000 | -0.1314 | No |
| 49 | NAP1L2 | nucleosome assembly protein 1 like 2 [Source:HGNC Symbol;Acc:HGNC:7638] | 12152 | 0.000 | -0.1348 | No |
| 50 | ITGBL1 | integrin subunit beta like 1 [Source:HGNC Symbol;Acc:HGNC:6164] | 12477 | 0.000 | -0.1436 | No |
| 51 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 12517 | 0.000 | -0.1447 | No |
| 52 | GAP43 | growth associated protein 43 [Source:HGNC Symbol;Acc:HGNC:4140] | 12834 | 0.000 | -0.1532 | No |
| 53 | GCGR | glucagon receptor [Source:HGNC Symbol;Acc:HGNC:4192] | 13155 | 0.000 | -0.1619 | No |
| 54 | ESRRG | estrogen related receptor gamma [Source:HGNC Symbol;Acc:HGNC:3474] | 13320 | 0.000 | -0.1663 | No |
| 55 | VIPR2 | vasoactive intestinal peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:12695] | 13409 | 0.000 | -0.1687 | No |
| 56 | RELN | reelin [Source:HGNC Symbol;Acc:HGNC:9957] | 13870 | 0.000 | -0.1811 | No |
| 57 | GHRH | growth hormone releasing hormone [Source:HGNC Symbol;Acc:HGNC:4265] | 15234 | 0.000 | -0.2180 | No |
| 58 | SV2B | synaptic vesicle glycoprotein 2B [Source:HGNC Symbol;Acc:HGNC:16874] | 15723 | 0.000 | -0.2312 | No |
| 59 | TCEAL2 | transcription elongation factor A like 2 [Source:HGNC Symbol;Acc:HGNC:29818] | 15962 | 0.000 | -0.2377 | No |
| 60 | XK | X-linked Kx blood group [Source:HGNC Symbol;Acc:HGNC:12811] | 16298 | 0.000 | -0.2467 | No |
| 61 | GPM6A | glycoprotein M6A [Source:HGNC Symbol;Acc:HGNC:4460] | 16595 | 0.000 | -0.2548 | No |
| 62 | TRIB2 | tribbles pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:30809] | 16877 | 0.000 | -0.2624 | No |
| 63 | SYT1 | synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509] | 17038 | 0.000 | -0.2667 | No |
| 64 | GPR37 | G protein-coupled receptor 37 [Source:HGNC Symbol;Acc:HGNC:4494] | 17547 | 0.000 | -0.2804 | No |
| 65 | SLC12A3 | solute carrier family 12 member 3 [Source:HGNC Symbol;Acc:HGNC:10912] | 17627 | 0.000 | -0.2826 | No |
| 66 | TRIM9 | tripartite motif containing 9 [Source:HGNC Symbol;Acc:HGNC:16288] | 17859 | 0.000 | -0.2888 | No |
| 67 | KIT | KIT proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6342] | 18357 | 0.000 | -0.3023 | No |
| 68 | FZD3 | frizzled class receptor 3 [Source:HGNC Symbol;Acc:HGNC:4041] | 19306 | 0.000 | -0.3279 | No |
| 69 | NDN | necdin, MAGE family member [Source:HGNC Symbol;Acc:HGNC:7675] | 19367 | 0.000 | -0.3295 | No |
| 70 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 20048 | 0.000 | -0.3480 | No |
| 71 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 20092 | 0.000 | -0.3491 | No |
| 72 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 20095 | 0.000 | -0.3492 | No |
| 73 | NOL4 | nucleolar protein 4 [Source:HGNC Symbol;Acc:HGNC:7870] | 20439 | 0.000 | -0.3585 | No |
| 74 | WIF1 | WNT inhibitory factor 1 [Source:HGNC Symbol;Acc:HGNC:18081] | 20442 | 0.000 | -0.3585 | No |
| 75 | CFAP69 | cilia and flagella associated protein 69 [Source:HGNC Symbol;Acc:HGNC:26107] | 20541 | 0.000 | -0.3612 | No |
| 76 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 20752 | 0.000 | -0.3668 | No |
| 77 | DLGAP2 | DLG associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2906] | 21238 | 0.000 | -0.3800 | No |
| 78 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 21325 | 0.000 | -0.3823 | No |
| 79 | FAM153B | family with sequence similarity 153 member B [Source:HGNC Symbol;Acc:HGNC:27323] | 21576 | 0.000 | -0.3891 | No |
| 80 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 21603 | 0.000 | -0.3898 | No |
| 81 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 21873 | 0.000 | -0.3970 | No |
| 82 | LMO3 | LIM domain only 3 [Source:HGNC Symbol;Acc:HGNC:6643] | 21949 | 0.000 | -0.3991 | No |
| 83 | ANK3 | ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494] | 22238 | 0.000 | -0.4069 | No |
| 84 | FGF9 | fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687] | 22762 | 0.000 | -0.4210 | No |
| 85 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 23042 | 0.000 | -0.4286 | No |
| 86 | SOBP | sine oculis binding protein homolog [Source:HGNC Symbol;Acc:HGNC:29256] | 23338 | 0.000 | -0.4366 | No |
| 87 | SLC6A1 | solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042] | 23428 | 0.000 | -0.4390 | No |
| 88 | PLCB1 | phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917] | 23446 | 0.000 | -0.4394 | No |
| 89 | PNMA2 | PNMA family member 2 [Source:HGNC Symbol;Acc:HGNC:9159] | 23916 | 0.000 | -0.4521 | No |
| 90 | MAGEH1 | MAGE family member H1 [Source:HGNC Symbol;Acc:HGNC:24092] | 24165 | 0.000 | -0.4588 | No |
| 91 | A2M | alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7] | 24425 | 0.000 | -0.4658 | No |
| 92 | SLC1A3 | solute carrier family 1 member 3 [Source:HGNC Symbol;Acc:HGNC:10941] | 24482 | 0.000 | -0.4673 | No |
| 93 | PLGLA | plasminogen like A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:9074] | 24537 | 0.000 | -0.4688 | No |
| 94 | AK5 | adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365] | 24671 | 0.000 | -0.4724 | No |
| 95 | RCAN2 | regulator of calcineurin 2 [Source:HGNC Symbol;Acc:HGNC:3041] | 24710 | 0.000 | -0.4734 | No |
| 96 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 24870 | 0.000 | -0.4777 | No |
| 97 | SCN2A | sodium voltage-gated channel alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:10588] | 25074 | 0.000 | -0.4832 | No |
| 98 | MMP27 | matrix metallopeptidase 27 [Source:HGNC Symbol;Acc:HGNC:14250] | 25696 | 0.000 | -0.5000 | No |
| 99 | RIT2 | Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HGNC:10017] | 25790 | 0.000 | -0.5026 | No |
| 100 | PCP4 | Purkinje cell protein 4 [Source:HGNC Symbol;Acc:HGNC:8742] | 25816 | 0.000 | -0.5032 | No |
| 101 | ARPP21 | cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968] | 25909 | 0.000 | -0.5057 | No |
| 102 | PEG3 | paternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:8826] | 26423 | 0.000 | -0.5196 | No |
| 103 | SATB1 | SATB homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10541] | 26566 | 0.000 | -0.5234 | No |
| 104 | TRIL | TLR4 interactor with leucine rich repeats [Source:HGNC Symbol;Acc:HGNC:22200] | 26731 | 0.000 | -0.5279 | No |
| 105 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 26872 | 0.000 | -0.5317 | No |
| 106 | NRCAM | neuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994] | 27785 | 0.000 | -0.5564 | No |
| 107 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 28407 | 0.000 | -0.5732 | No |
| 108 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 29254 | -0.188 | -0.5934 | No |
| 109 | CPEB3 | cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:21746] | 29410 | -0.219 | -0.5944 | No |
| 110 | CPE | carboxypeptidase E [Source:HGNC Symbol;Acc:HGNC:2303] | 29878 | -0.328 | -0.6024 | No |
| 111 | NUDT11 | nudix hydrolase 11 [Source:HGNC Symbol;Acc:HGNC:18011] | 29907 | -0.333 | -0.5984 | No |
| 112 | SLC12A5 | solute carrier family 12 member 5 [Source:HGNC Symbol;Acc:HGNC:13818] | 30244 | -0.417 | -0.6015 | No |
| 113 | SELENOP | selenoprotein P [Source:HGNC Symbol;Acc:HGNC:10751] | 30294 | -0.431 | -0.5967 | No |
| 114 | DNM3 | dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125] | 30446 | -0.479 | -0.5940 | No |
| 115 | ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080] | 30599 | -0.512 | -0.5908 | No |
| 116 | ANK2 | ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493] | 31940 | -0.892 | -0.6143 | No |
| 117 | SERPINI1 | serpin family I member 1 [Source:HGNC Symbol;Acc:HGNC:8943] | 32580 | -1.109 | -0.6157 | Yes |
| 118 | TSPAN7 | tetraspanin 7 [Source:HGNC Symbol;Acc:HGNC:11854] | 32662 | -1.136 | -0.6017 | Yes |
| 119 | TMEM100 | transmembrane protein 100 [Source:HGNC Symbol;Acc:HGNC:25607] | 32750 | -1.163 | -0.5874 | Yes |
| 120 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 32997 | -1.257 | -0.5761 | Yes |
| 121 | MAFB | MAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408] | 33055 | -1.276 | -0.5595 | Yes |
| 122 | DUSP6 | dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072] | 34100 | -1.666 | -0.5639 | Yes |
| 123 | TMOD1 | tropomodulin 1 [Source:HGNC Symbol;Acc:HGNC:11871] | 34145 | -1.687 | -0.5410 | Yes |
| 124 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 34146 | -1.687 | -0.5169 | Yes |
| 125 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 34230 | -1.732 | -0.4944 | Yes |
| 126 | TUBB4A | tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774] | 34268 | -1.750 | -0.4705 | Yes |
| 127 | KIF5C | kinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325] | 34412 | -1.813 | -0.4484 | Yes |
| 128 | GATM | glycine amidinotransferase [Source:HGNC Symbol;Acc:HGNC:4175] | 35120 | -2.265 | -0.4352 | Yes |
| 129 | NRN1 | neuritin 1 [Source:HGNC Symbol;Acc:HGNC:17972] | 35198 | -2.312 | -0.4043 | Yes |
| 130 | ATP1A2 | ATPase Na+/K+ transporting subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:800] | 36022 | -2.955 | -0.3844 | Yes |
| 131 | GPR19 | G protein-coupled receptor 19 [Source:HGNC Symbol;Acc:HGNC:4473] | 36165 | -3.120 | -0.3437 | Yes |
| 132 | MEF2C | myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996] | 36286 | -3.223 | -0.3009 | Yes |
| 133 | GPNMB | glycoprotein nmb [Source:HGNC Symbol;Acc:HGNC:4462] | 36436 | -3.433 | -0.2559 | Yes |
| 134 | SORBS1 | sorbin and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14565] | 36572 | -3.604 | -0.2081 | Yes |
| 135 | PLP1 | proteolipid protein 1 [Source:HGNC Symbol;Acc:HGNC:9086] | 36665 | -3.749 | -0.1570 | Yes |
| 136 | TRIM2 | tripartite motif containing 2 [Source:HGNC Symbol;Acc:HGNC:15974] | 36668 | -3.755 | -0.1035 | Yes |
| 137 | SORL1 | sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185] | 36717 | -3.849 | -0.0498 | Yes |
| 138 | METTL7A | methyltransferase like 7A [Source:HGNC Symbol;Acc:HGNC:24550] | 36882 | -4.192 | 0.0056 | Yes |
