Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.5521499 |
| Normalized Enrichment Score (NES) | 1.4204247 |
| Nominal p-value | 0.007142857 |
| FDR q-value | 0.13324735 |
| FWER p-Value | 0.192 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 8 | 4.983 | 0.0367 | Yes |
| 2 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 21 | 4.911 | 0.0728 | Yes |
| 3 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 42 | 4.786 | 0.1078 | Yes |
| 4 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 114 | 4.297 | 0.1377 | Yes |
| 5 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 121 | 4.254 | 0.1691 | Yes |
| 6 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 141 | 4.157 | 0.1995 | Yes |
| 7 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 160 | 4.087 | 0.2293 | Yes |
| 8 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 331 | 3.458 | 0.2503 | Yes |
| 9 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 492 | 2.954 | 0.2679 | Yes |
| 10 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 536 | 2.857 | 0.2879 | Yes |
| 11 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 606 | 2.685 | 0.3060 | Yes |
| 12 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 614 | 2.676 | 0.3256 | Yes |
| 13 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 616 | 2.675 | 0.3455 | Yes |
| 14 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 715 | 2.584 | 0.3620 | Yes |
| 15 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 768 | 2.480 | 0.3790 | Yes |
| 16 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 995 | 2.163 | 0.3889 | Yes |
| 17 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 1066 | 2.068 | 0.4023 | Yes |
| 18 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 1090 | 2.036 | 0.4168 | Yes |
| 19 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 1343 | 1.876 | 0.4239 | Yes |
| 20 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 1437 | 1.755 | 0.4344 | Yes |
| 21 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 1470 | 1.727 | 0.4464 | Yes |
| 22 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 1581 | 1.643 | 0.4556 | Yes |
| 23 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 1930 | 1.394 | 0.4565 | Yes |
| 24 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 2315 | 1.215 | 0.4551 | Yes |
| 25 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 2366 | 1.186 | 0.4626 | Yes |
| 26 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 2550 | 1.111 | 0.4659 | Yes |
| 27 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 2619 | 1.080 | 0.4720 | Yes |
| 28 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 2745 | 1.028 | 0.4763 | Yes |
| 29 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2792 | 1.009 | 0.4825 | Yes |
| 30 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 2830 | 0.993 | 0.4889 | Yes |
| 31 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 2862 | 0.978 | 0.4953 | Yes |
| 32 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 2873 | 0.970 | 0.5022 | Yes |
| 33 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 2887 | 0.962 | 0.5090 | Yes |
| 34 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 2921 | 0.947 | 0.5151 | Yes |
| 35 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 3053 | 0.903 | 0.5183 | Yes |
| 36 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 3089 | 0.886 | 0.5239 | Yes |
| 37 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 3098 | 0.883 | 0.5302 | Yes |
| 38 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 3111 | 0.878 | 0.5364 | Yes |
| 39 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 3368 | 0.786 | 0.5353 | Yes |
| 40 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 3436 | 0.759 | 0.5391 | Yes |
| 41 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 3461 | 0.751 | 0.5441 | Yes |
| 42 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 3616 | 0.699 | 0.5451 | Yes |
| 43 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 3625 | 0.697 | 0.5500 | Yes |
| 44 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3839 | 0.625 | 0.5489 | Yes |
| 45 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3975 | 0.586 | 0.5496 | Yes |
| 46 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 4038 | 0.570 | 0.5521 | Yes |
| 47 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 4398 | 0.465 | 0.5459 | No |
| 48 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 4473 | 0.437 | 0.5471 | No |
| 49 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4500 | 0.431 | 0.5496 | No |
| 50 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 4532 | 0.421 | 0.5519 | No |
| 51 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 4713 | 0.371 | 0.5498 | No |
| 52 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 4897 | 0.318 | 0.5472 | No |
| 53 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 4901 | 0.318 | 0.5495 | No |
| 54 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 4959 | 0.302 | 0.5502 | No |
| 55 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 5109 | 0.255 | 0.5480 | No |
| 56 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 5124 | 0.250 | 0.5495 | No |
| 57 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 5203 | 0.239 | 0.5492 | No |
| 58 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 5981 | 0.105 | 0.5289 | No |
| 59 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 6002 | 0.098 | 0.5291 | No |
| 60 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 6110 | 0.066 | 0.5267 | No |
| 61 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 6531 | 0.000 | 0.5153 | No |
| 62 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 8868 | 0.000 | 0.4522 | No |
| 63 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9419 | 0.000 | 0.4373 | No |
| 64 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9779 | 0.000 | 0.4276 | No |
| 65 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9979 | 0.000 | 0.4222 | No |
| 66 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10052 | 0.000 | 0.4202 | No |
| 67 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11060 | 0.000 | 0.3930 | No |
| 68 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11186 | 0.000 | 0.3896 | No |
| 69 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11228 | 0.000 | 0.3885 | No |
| 70 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11815 | 0.000 | 0.3727 | No |
| 71 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11895 | 0.000 | 0.3705 | No |
| 72 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12231 | 0.000 | 0.3615 | No |
| 73 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12476 | 0.000 | 0.3549 | No |
| 74 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 13036 | 0.000 | 0.3397 | No |
| 75 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 13490 | 0.000 | 0.3275 | No |
| 76 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13881 | 0.000 | 0.3169 | No |
| 77 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14206 | 0.000 | 0.3082 | No |
| 78 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16373 | 0.000 | 0.2496 | No |
| 79 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17163 | 0.000 | 0.2282 | No |
| 80 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18048 | 0.000 | 0.2043 | No |
| 81 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19376 | 0.000 | 0.1684 | No |
| 82 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 20109 | 0.000 | 0.1486 | No |
| 83 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 20886 | 0.000 | 0.1276 | No |
| 84 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 21694 | 0.000 | 0.1058 | No |
| 85 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 21910 | 0.000 | 0.1000 | No |
| 86 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 22324 | 0.000 | 0.0888 | No |
| 87 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 23203 | 0.000 | 0.0651 | No |
| 88 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 24017 | 0.000 | 0.0431 | No |
| 89 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 24427 | 0.000 | 0.0320 | No |
| 90 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 24514 | 0.000 | 0.0297 | No |
| 91 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 24781 | 0.000 | 0.0225 | No |
| 92 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 25913 | 0.000 | -0.0081 | No |
| 93 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 26162 | 0.000 | -0.0148 | No |
| 94 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 26923 | 0.000 | -0.0354 | No |
| 95 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 27879 | 0.000 | -0.0612 | No |
| 96 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 28559 | -0.010 | -0.0795 | No |
| 97 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 28600 | -0.021 | -0.0804 | No |
| 98 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 29116 | -0.151 | -0.0932 | No |
| 99 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 30391 | -0.460 | -0.1243 | No |
| 100 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 30509 | -0.486 | -0.1238 | No |
| 101 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 30757 | -0.556 | -0.1264 | No |
| 102 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 30828 | -0.573 | -0.1240 | No |
| 103 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 31171 | -0.666 | -0.1284 | No |
| 104 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 31399 | -0.731 | -0.1291 | No |
| 105 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 31486 | -0.759 | -0.1258 | No |
| 106 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 31790 | -0.834 | -0.1278 | No |
| 107 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 31955 | -0.899 | -0.1255 | No |
| 108 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 32348 | -1.026 | -0.1285 | No |
| 109 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 32549 | -1.100 | -0.1258 | No |
| 110 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 32905 | -1.222 | -0.1263 | No |
| 111 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 33733 | -1.487 | -0.1377 | No |
| 112 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 33852 | -1.538 | -0.1294 | No |
| 113 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 33898 | -1.557 | -0.1191 | No |
| 114 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 34408 | -1.811 | -0.1195 | No |
| 115 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 34559 | -1.898 | -0.1094 | No |
| 116 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 34986 | -2.162 | -0.1049 | No |
| 117 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 35486 | -2.466 | -0.1001 | No |
| 118 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 36021 | -2.953 | -0.0927 | No |
| 119 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 36137 | -3.089 | -0.0729 | No |
| 120 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 36260 | -3.196 | -0.0525 | No |
| 121 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 36269 | -3.196 | -0.0290 | No |
| 122 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36384 | -3.370 | -0.0071 | No |
| 123 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36523 | -3.525 | 0.0153 | No |
