Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.6373379 |
| Normalized Enrichment Score (NES) | -1.3620689 |
| Nominal p-value | 0.0093240095 |
| FDR q-value | 0.20346715 |
| FWER p-Value | 0.813 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 41 | 4.787 | 0.0263 | No |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 125 | 4.243 | 0.0484 | No |
| 3 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 249 | 3.685 | 0.0662 | No |
| 4 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 902 | 2.287 | 0.0616 | No |
| 5 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 1076 | 2.054 | 0.0687 | No |
| 6 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1359 | 1.862 | 0.0718 | No |
| 7 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 1373 | 1.843 | 0.0820 | No |
| 8 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 1571 | 1.650 | 0.0861 | No |
| 9 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 1637 | 1.603 | 0.0935 | No |
| 10 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 1754 | 1.519 | 0.0991 | No |
| 11 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 1757 | 1.517 | 0.1077 | No |
| 12 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 2149 | 1.265 | 0.1044 | No |
| 13 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 2607 | 1.083 | 0.0982 | No |
| 14 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 3311 | 0.796 | 0.0838 | No |
| 15 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 3929 | 0.597 | 0.0705 | No |
| 16 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 4237 | 0.504 | 0.0651 | No |
| 17 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 5022 | 0.281 | 0.0455 | No |
| 18 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 5116 | 0.253 | 0.0444 | No |
| 19 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 6250 | 0.028 | 0.0139 | No |
| 20 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6691 | 0.000 | 0.0020 | No |
| 21 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7267 | 0.000 | -0.0135 | No |
| 22 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7555 | 0.000 | -0.0213 | No |
| 23 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 8342 | 0.000 | -0.0425 | No |
| 24 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8970 | 0.000 | -0.0595 | No |
| 25 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9377 | 0.000 | -0.0705 | No |
| 26 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9913 | 0.000 | -0.0849 | No |
| 27 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 9915 | 0.000 | -0.0850 | No |
| 28 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10017 | 0.000 | -0.0877 | No |
| 29 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10798 | 0.000 | -0.1088 | No |
| 30 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11647 | 0.000 | -0.1317 | No |
| 31 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12544 | 0.000 | -0.1560 | No |
| 32 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13448 | 0.000 | -0.1804 | No |
| 33 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 13954 | 0.000 | -0.1940 | No |
| 34 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14699 | 0.000 | -0.2142 | No |
| 35 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16026 | 0.000 | -0.2500 | No |
| 36 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16721 | 0.000 | -0.2688 | No |
| 37 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17096 | 0.000 | -0.2789 | No |
| 38 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19865 | 0.000 | -0.3538 | No |
| 39 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 20752 | 0.000 | -0.3777 | No |
| 40 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 21325 | 0.000 | -0.3932 | No |
| 41 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 22245 | 0.000 | -0.4181 | No |
| 42 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 23299 | 0.000 | -0.4465 | No |
| 43 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 25006 | 0.000 | -0.4927 | No |
| 44 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 25771 | 0.000 | -0.5134 | No |
| 45 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26911 | 0.000 | -0.5442 | No |
| 46 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 29705 | -0.292 | -0.6180 | No |
| 47 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 29866 | -0.323 | -0.6205 | No |
| 48 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 29869 | -0.324 | -0.6187 | No |
| 49 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30062 | -0.369 | -0.6218 | No |
| 50 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 30230 | -0.416 | -0.6239 | No |
| 51 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 30486 | -0.479 | -0.6281 | No |
| 52 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 30737 | -0.551 | -0.6317 | No |
| 53 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 30790 | -0.565 | -0.6298 | No |
| 54 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 31068 | -0.634 | -0.6337 | Yes |
| 55 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 31089 | -0.642 | -0.6306 | Yes |
| 56 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 31339 | -0.714 | -0.6332 | Yes |
| 57 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 31364 | -0.723 | -0.6297 | Yes |
| 58 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 31448 | -0.749 | -0.6277 | Yes |
| 59 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 31455 | -0.750 | -0.6235 | Yes |
| 60 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 31504 | -0.766 | -0.6204 | Yes |
| 61 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 31820 | -0.846 | -0.6241 | Yes |
| 62 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 32267 | -1.013 | -0.6304 | Yes |
| 63 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 32288 | -1.021 | -0.6251 | Yes |
| 64 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 32507 | -1.087 | -0.6247 | Yes |
| 65 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 32525 | -1.091 | -0.6190 | Yes |
| 66 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 32616 | -1.123 | -0.6150 | Yes |
| 67 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 32933 | -1.233 | -0.6164 | Yes |
| 68 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 33112 | -1.295 | -0.6138 | Yes |
| 69 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 33146 | -1.310 | -0.6072 | Yes |
| 70 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 33304 | -1.376 | -0.6036 | Yes |
| 71 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 33308 | -1.378 | -0.5958 | Yes |
| 72 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 33389 | -1.416 | -0.5898 | Yes |
| 73 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 33402 | -1.423 | -0.5820 | Yes |
| 74 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 33425 | -1.433 | -0.5744 | Yes |
| 75 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33437 | -1.439 | -0.5664 | Yes |
| 76 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 33676 | -1.467 | -0.5645 | Yes |
| 77 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 33693 | -1.471 | -0.5565 | Yes |
| 78 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33797 | -1.517 | -0.5506 | Yes |
| 79 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 33951 | -1.588 | -0.5456 | Yes |
| 80 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 34002 | -1.616 | -0.5377 | Yes |
| 81 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 34130 | -1.676 | -0.5315 | Yes |
| 82 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 34856 | -2.081 | -0.5392 | Yes |
| 83 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 34869 | -2.092 | -0.5276 | Yes |
| 84 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 34924 | -2.128 | -0.5168 | Yes |
| 85 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 34930 | -2.131 | -0.5048 | Yes |
| 86 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 35082 | -2.234 | -0.4961 | Yes |
| 87 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 35167 | -2.300 | -0.4852 | Yes |
| 88 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35200 | -2.313 | -0.4728 | Yes |
| 89 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35489 | -2.468 | -0.4664 | Yes |
| 90 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35503 | -2.478 | -0.4526 | Yes |
| 91 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 35509 | -2.483 | -0.4385 | Yes |
| 92 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35520 | -2.493 | -0.4245 | Yes |
| 93 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 35566 | -2.530 | -0.4112 | Yes |
| 94 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 35623 | -2.585 | -0.3979 | Yes |
| 95 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 35670 | -2.611 | -0.3842 | Yes |
| 96 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 35711 | -2.650 | -0.3701 | Yes |
| 97 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 35808 | -2.743 | -0.3570 | Yes |
| 98 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35813 | -2.748 | -0.3414 | Yes |
| 99 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35826 | -2.754 | -0.3259 | Yes |
| 100 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35848 | -2.786 | -0.3105 | Yes |
| 101 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 35861 | -2.792 | -0.2948 | Yes |
| 102 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 35895 | -2.842 | -0.2794 | Yes |
| 103 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 36071 | -2.998 | -0.2670 | Yes |
| 104 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36171 | -3.135 | -0.2517 | Yes |
| 105 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36208 | -3.182 | -0.2345 | Yes |
| 106 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36279 | -3.215 | -0.2179 | Yes |
| 107 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36380 | -3.365 | -0.2014 | Yes |
| 108 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36383 | -3.368 | -0.1821 | Yes |
| 109 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36496 | -3.483 | -0.1652 | Yes |
| 110 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36504 | -3.497 | -0.1454 | Yes |
| 111 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36623 | -3.678 | -0.1275 | Yes |
| 112 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 36708 | -3.829 | -0.1078 | Yes |
| 113 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36709 | -3.830 | -0.0859 | Yes |
| 114 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36799 | -4.008 | -0.0653 | Yes |
| 115 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36833 | -4.057 | -0.0430 | Yes |
| 116 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 36853 | -4.111 | -0.0200 | Yes |
| 117 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 37012 | -4.598 | 0.0021 | Yes |
