Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.7165409 |
| Normalized Enrichment Score (NES) | -1.565373 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.019373024 |
| FWER p-Value | 0.022 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 133 | 4.197 | 0.0192 | No |
| 2 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 519 | 2.889 | 0.0244 | No |
| 3 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 979 | 2.181 | 0.0238 | No |
| 4 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 1209 | 1.885 | 0.0278 | No |
| 5 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 1308 | 1.876 | 0.0354 | No |
| 6 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 1410 | 1.788 | 0.0423 | No |
| 7 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 1464 | 1.735 | 0.0503 | No |
| 8 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 1754 | 1.519 | 0.0507 | No |
| 9 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1988 | 1.364 | 0.0518 | No |
| 10 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 3171 | 0.854 | 0.0244 | No |
| 11 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 3387 | 0.780 | 0.0228 | No |
| 12 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 3684 | 0.681 | 0.0185 | No |
| 13 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 5097 | 0.258 | -0.0183 | No |
| 14 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 5116 | 0.253 | -0.0174 | No |
| 15 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 6020 | 0.092 | -0.0413 | No |
| 16 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6761 | 0.000 | -0.0613 | No |
| 17 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8207 | 0.000 | -0.1004 | No |
| 18 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9703 | 0.000 | -0.1409 | No |
| 19 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 9747 | 0.000 | -0.1421 | No |
| 20 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10629 | 0.000 | -0.1659 | No |
| 21 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12181 | 0.000 | -0.2079 | No |
| 22 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12433 | 0.000 | -0.2146 | No |
| 23 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12585 | 0.000 | -0.2187 | No |
| 24 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 12596 | 0.000 | -0.2190 | No |
| 25 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12629 | 0.000 | -0.2199 | No |
| 26 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12908 | 0.000 | -0.2274 | No |
| 27 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 12909 | 0.000 | -0.2274 | No |
| 28 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13524 | 0.000 | -0.2440 | No |
| 29 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 13855 | 0.000 | -0.2529 | No |
| 30 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14853 | 0.000 | -0.2799 | No |
| 31 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15518 | 0.000 | -0.2979 | No |
| 32 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 15529 | 0.000 | -0.2981 | No |
| 33 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16026 | 0.000 | -0.3116 | No |
| 34 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16268 | 0.000 | -0.3181 | No |
| 35 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16345 | 0.000 | -0.3201 | No |
| 36 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16496 | 0.000 | -0.3242 | No |
| 37 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16597 | 0.000 | -0.3269 | No |
| 38 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 17023 | 0.000 | -0.3384 | No |
| 39 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17569 | 0.000 | -0.3531 | No |
| 40 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18797 | 0.000 | -0.3863 | No |
| 41 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18798 | 0.000 | -0.3863 | No |
| 42 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 19075 | 0.000 | -0.3938 | No |
| 43 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19768 | 0.000 | -0.4125 | No |
| 44 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19913 | 0.000 | -0.4164 | No |
| 45 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 21286 | 0.000 | -0.4535 | No |
| 46 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 21493 | 0.000 | -0.4591 | No |
| 47 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 23056 | 0.000 | -0.5014 | No |
| 48 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 25132 | 0.000 | -0.5575 | No |
| 49 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 25617 | 0.000 | -0.5706 | No |
| 50 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 26113 | 0.000 | -0.5840 | No |
| 51 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 26353 | 0.000 | -0.5905 | No |
| 52 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 26609 | 0.000 | -0.5974 | No |
| 53 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26911 | 0.000 | -0.6055 | No |
| 54 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 27518 | 0.000 | -0.6219 | No |
| 55 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 28523 | -0.001 | -0.6491 | No |
| 56 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 29273 | -0.191 | -0.6683 | No |
| 57 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 29349 | -0.209 | -0.6692 | No |
| 58 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 29353 | -0.211 | -0.6681 | No |
| 59 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 29599 | -0.262 | -0.6733 | No |
| 60 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 29625 | -0.271 | -0.6725 | No |
| 61 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 29982 | -0.347 | -0.6803 | No |
| 62 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30062 | -0.369 | -0.6804 | No |
| 63 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 30378 | -0.455 | -0.6865 | No |
| 64 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 30544 | -0.497 | -0.6883 | No |
| 65 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 31031 | -0.622 | -0.6980 | No |
| 66 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 31041 | -0.624 | -0.6949 | No |
| 67 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 31199 | -0.672 | -0.6955 | No |
| 68 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 31235 | -0.683 | -0.6927 | No |
| 69 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 31236 | -0.683 | -0.6890 | No |
| 70 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 31258 | -0.691 | -0.6859 | No |
| 71 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31400 | -0.732 | -0.6857 | No |
| 72 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31861 | -0.859 | -0.6935 | No |
| 73 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32513 | -1.089 | -0.7052 | No |
| 74 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 32933 | -1.233 | -0.7099 | Yes |
| 75 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 32997 | -1.257 | -0.7047 | Yes |
| 76 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 33285 | -1.369 | -0.7051 | Yes |
| 77 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 33304 | -1.376 | -0.6981 | Yes |
| 78 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33437 | -1.439 | -0.6939 | Yes |
| 79 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 33676 | -1.467 | -0.6924 | Yes |
| 80 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 33781 | -1.511 | -0.6870 | Yes |
| 81 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33797 | -1.517 | -0.6792 | Yes |
| 82 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 33825 | -1.530 | -0.6716 | Yes |
| 83 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 34091 | -1.662 | -0.6698 | Yes |
| 84 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 34475 | -1.843 | -0.6701 | Yes |
| 85 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34482 | -1.849 | -0.6603 | Yes |
| 86 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 34589 | -1.916 | -0.6528 | Yes |
| 87 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34720 | -1.982 | -0.6455 | Yes |
| 88 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 34774 | -2.027 | -0.6360 | Yes |
| 89 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34782 | -2.033 | -0.6251 | Yes |
| 90 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 34815 | -2.058 | -0.6149 | Yes |
| 91 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35007 | -2.177 | -0.6082 | Yes |
| 92 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35037 | -2.200 | -0.5971 | Yes |
| 93 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 35121 | -2.265 | -0.5870 | Yes |
| 94 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35370 | -2.370 | -0.5809 | Yes |
| 95 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35378 | -2.378 | -0.5682 | Yes |
| 96 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 35410 | -2.398 | -0.5560 | Yes |
| 97 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35520 | -2.493 | -0.5455 | Yes |
| 98 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 35566 | -2.530 | -0.5330 | Yes |
| 99 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35567 | -2.531 | -0.5192 | Yes |
| 100 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 35594 | -2.560 | -0.5061 | Yes |
| 101 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35813 | -2.748 | -0.4971 | Yes |
| 102 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35826 | -2.754 | -0.4825 | Yes |
| 103 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 35970 | -2.892 | -0.4707 | Yes |
| 104 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 35989 | -2.912 | -0.4554 | Yes |
| 105 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36019 | -2.949 | -0.4402 | Yes |
| 106 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36026 | -2.958 | -0.4243 | Yes |
| 107 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 36078 | -3.003 | -0.4094 | Yes |
| 108 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36079 | -3.005 | -0.3931 | Yes |
| 109 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 36179 | -3.142 | -0.3787 | Yes |
| 110 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 36184 | -3.151 | -0.3618 | Yes |
| 111 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36193 | -3.164 | -0.3448 | Yes |
| 112 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36290 | -3.231 | -0.3299 | Yes |
| 113 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36293 | -3.235 | -0.3124 | Yes |
| 114 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36311 | -3.256 | -0.2952 | Yes |
| 115 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36317 | -3.261 | -0.2777 | Yes |
| 116 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36324 | -3.271 | -0.2601 | Yes |
| 117 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 36354 | -3.331 | -0.2428 | Yes |
| 118 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 36368 | -3.349 | -0.2250 | Yes |
| 119 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36383 | -3.368 | -0.2072 | Yes |
| 120 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36435 | -3.432 | -0.1899 | Yes |
| 121 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36496 | -3.483 | -0.1727 | Yes |
| 122 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36504 | -3.497 | -0.1539 | Yes |
| 123 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36530 | -3.547 | -0.1354 | Yes |
| 124 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36548 | -3.570 | -0.1165 | Yes |
| 125 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36623 | -3.678 | -0.0985 | Yes |
| 126 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.858 | -0.0803 | Yes |
| 127 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36799 | -4.008 | -0.0606 | Yes |
| 128 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36851 | -4.106 | -0.0397 | Yes |
| 129 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36893 | -4.218 | -0.0179 | Yes |
| 130 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 36920 | -4.289 | 0.0046 | Yes |
