Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | BUSSLINGER_DUODENAL_EC_CELLS |
| Enrichment Score (ES) | 0.7997272 |
| Normalized Enrichment Score (NES) | 1.6231334 |
| Nominal p-value | 0.017006803 |
| FDR q-value | 0.081060216 |
| FWER p-Value | 0.317 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 41 | 4.787 | 0.2020 | Yes |
| 2 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 123 | 4.245 | 0.3800 | Yes |
| 3 | MAP1B | microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] | 159 | 4.096 | 0.5528 | Yes |
| 4 | SCG2 | secretogranin II [Source:HGNC Symbol;Acc:HGNC:10575] | 352 | 3.350 | 0.6898 | Yes |
| 5 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 589 | 2.742 | 0.7997 | Yes |
| 6 | SCGN | secretagogin, EF-hand calcium binding protein [Source:HGNC Symbol;Acc:HGNC:16941] | 6563 | 0.000 | 0.6386 | No |
| 7 | CRYBA2 | crystallin beta A2 [Source:HGNC Symbol;Acc:HGNC:2395] | 8829 | 0.000 | 0.5774 | No |
| 8 | CES1 | carboxylesterase 1 [Source:HGNC Symbol;Acc:HGNC:1863] | 9911 | 0.000 | 0.5483 | No |
| 9 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10616 | 0.000 | 0.5293 | No |
| 10 | CHGB | chromogranin B [Source:HGNC Symbol;Acc:HGNC:1930] | 10637 | 0.000 | 0.5287 | No |
| 11 | MS4A8 | membrane spanning 4-domains A8 [Source:HGNC Symbol;Acc:HGNC:13380] | 11154 | 0.000 | 0.5148 | No |
| 12 | ADH4 | alcohol dehydrogenase 4 (class II), pi polypeptide [Source:HGNC Symbol;Acc:HGNC:252] | 11208 | 0.000 | 0.5134 | No |
| 13 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11895 | 0.000 | 0.4949 | No |
| 14 | LCN15 | lipocalin 15 [Source:HGNC Symbol;Acc:HGNC:33777] | 11983 | 0.000 | 0.4925 | No |
| 15 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12716 | 0.000 | 0.4728 | No |
| 16 | REG4 | regenerating family member 4 [Source:HGNC Symbol;Acc:HGNC:22977] | 13804 | 0.000 | 0.4434 | No |
| 17 | DDC | dopa decarboxylase [Source:HGNC Symbol;Acc:HGNC:2719] | 16035 | 0.000 | 0.3833 | No |
| 18 | GC | GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187] | 16176 | 0.000 | 0.3795 | No |
| 19 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16274 | 0.000 | 0.3769 | No |
| 20 | PCSK1 | proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743] | 16275 | 0.000 | 0.3769 | No |
| 21 | CDHR3 | cadherin related family member 3 [Source:HGNC Symbol;Acc:HGNC:26308] | 19214 | 0.000 | 0.2976 | No |
| 22 | NEUROD1 | neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7762] | 19362 | 0.000 | 0.2936 | No |
| 23 | ADGRG4 | adhesion G protein-coupled receptor G4 [Source:HGNC Symbol;Acc:HGNC:18992] | 21510 | 0.000 | 0.2357 | No |
| 24 | TFF3 | trefoil factor 3 [Source:HGNC Symbol;Acc:HGNC:11757] | 25488 | 0.000 | 0.1284 | No |
| 25 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 25563 | 0.000 | 0.1264 | No |
| 26 | SCT | secretin [Source:HGNC Symbol;Acc:HGNC:10607] | 25624 | 0.000 | 0.1248 | No |
| 27 | SPINK1 | serine peptidase inhibitor Kazal type 1 [Source:HGNC Symbol;Acc:HGNC:11244] | 25809 | 0.000 | 0.1198 | No |
| 28 | RAB3C | RAB3C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30269] | 28864 | -0.088 | 0.0411 | No |
| 29 | FEV | FEV transcription factor, ETS family member [Source:HGNC Symbol;Acc:HGNC:18562] | 31565 | -0.768 | 0.0009 | No |
| 30 | CADPS | calcium dependent secretion activator [Source:HGNC Symbol;Acc:HGNC:1426] | 32559 | -1.103 | 0.0209 | No |
| 31 | RGS2 | regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998] | 35394 | -2.388 | 0.0458 | No |
