Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | DESCARTES_FETAL_SPLEEN_MYELOID_CELLS |
| Enrichment Score (ES) | 0.5832227 |
| Normalized Enrichment Score (NES) | 1.4921186 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.15194078 |
| FWER p-Value | 0.739 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.996 | 0.0422 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.975 | 0.0842 | Yes |
| 3 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 22 | 4.908 | 0.1255 | Yes |
| 4 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 131 | 4.203 | 0.1582 | Yes |
| 5 | ANKRD24 | ankyrin repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:29424] | 166 | 4.055 | 0.1916 | Yes |
| 6 | LY96 | lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156] | 206 | 3.851 | 0.2232 | Yes |
| 7 | RGS1 | regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991] | 336 | 3.436 | 0.2488 | Yes |
| 8 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 350 | 3.351 | 0.2768 | Yes |
| 9 | MNDA | myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183] | 393 | 3.231 | 0.3031 | Yes |
| 10 | NLRP3 | NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400] | 404 | 3.192 | 0.3298 | Yes |
| 11 | NABP1 | nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232] | 412 | 3.162 | 0.3564 | Yes |
| 12 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 454 | 3.073 | 0.3813 | Yes |
| 13 | GHRL | ghrelin and obestatin prepropeptide [Source:HGNC Symbol;Acc:HGNC:18129] | 526 | 2.878 | 0.4038 | Yes |
| 14 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 669 | 2.666 | 0.4225 | Yes |
| 15 | KCNAB1 | potassium voltage-gated channel subfamily A member regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6228] | 718 | 2.582 | 0.4431 | Yes |
| 16 | ITGAX | integrin subunit alpha X [Source:HGNC Symbol;Acc:HGNC:6152] | 824 | 2.386 | 0.4605 | Yes |
| 17 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 890 | 2.298 | 0.4782 | Yes |
| 18 | ITGAD | integrin subunit alpha D [Source:HGNC Symbol;Acc:HGNC:6146] | 911 | 2.273 | 0.4969 | Yes |
| 19 | RASSF4 | Ras association domain family member 4 [Source:HGNC Symbol;Acc:HGNC:20793] | 1387 | 1.820 | 0.4995 | Yes |
| 20 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1502 | 1.710 | 0.5109 | Yes |
| 21 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 1545 | 1.668 | 0.5239 | Yes |
| 22 | SMIM35 | small integral membrane protein 35 [Source:HGNC Symbol;Acc:HGNC:44179] | 1600 | 1.627 | 0.5362 | Yes |
| 23 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 1976 | 1.372 | 0.5377 | Yes |
| 24 | NCF2 | neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661] | 2003 | 1.354 | 0.5484 | Yes |
| 25 | NOD2 | nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331] | 2208 | 1.232 | 0.5533 | Yes |
| 26 | CD200R1 | CD200 receptor 1 [Source:HGNC Symbol;Acc:HGNC:24235] | 2226 | 1.227 | 0.5633 | Yes |
| 27 | PID1 | phosphotyrosine interaction domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26084] | 2412 | 1.164 | 0.5681 | Yes |
| 28 | KCNMA1 | potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284] | 2447 | 1.148 | 0.5769 | Yes |
| 29 | NAIP | NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634] | 2562 | 1.106 | 0.5832 | Yes |
| 30 | ZNF415P1 | zinc finger protein 415 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49869] | 3445 | 0.757 | 0.5658 | No |
| 31 | CABP4 | calcium binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1386] | 3873 | 0.615 | 0.5594 | No |
| 32 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 4015 | 0.574 | 0.5605 | No |
| 33 | FMN1 | formin 1 [Source:HGNC Symbol;Acc:HGNC:3768] | 4332 | 0.480 | 0.5560 | No |
| 34 | FABP5 | fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560] | 4965 | 0.301 | 0.5414 | No |
| 35 | VSIG4 | V-set and immunoglobulin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:17032] | 6521 | 0.000 | 0.4994 | No |
| 36 | LINC01645 | long intergenic non-protein coding RNA 1645 [Source:HGNC Symbol;Acc:HGNC:52432] | 7339 | 0.000 | 0.4773 | No |
| 37 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7817 | 0.000 | 0.4644 | No |
| 38 | EPB41L3 | erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380] | 8101 | 0.000 | 0.4567 | No |
| 39 | RASGEF1C | RasGEF domain family member 1C [Source:HGNC Symbol;Acc:HGNC:27400] | 8323 | 0.000 | 0.4507 | No |
| 40 | FCAR | Fc fragment of IgA receptor [Source:HGNC Symbol;Acc:HGNC:3608] | 8429 | 0.000 | 0.4479 | No |
| 41 | FCN1 | ficolin 1 [Source:HGNC Symbol;Acc:HGNC:3623] | 8507 | 0.000 | 0.4458 | No |
| 42 | AL606970.3 | novel transcript | 8511 | 0.000 | 0.4457 | No |
| 43 | BATF3 | basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915] | 8983 | 0.000 | 0.4330 | No |
| 44 | CLEC7A | C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558] | 9505 | 0.000 | 0.4189 | No |
| 45 | CARD14 | caspase recruitment domain family member 14 [Source:HGNC Symbol;Acc:HGNC:16446] | 9983 | 0.000 | 0.4060 | No |
| 46 | ADGRE4P | adhesion G protein-coupled receptor E4, pseudogene [Source:HGNC Symbol;Acc:HGNC:19240] | 10636 | 0.000 | 0.3884 | No |
| 47 | CHN2 | chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944] | 10705 | 0.000 | 0.3865 | No |
| 48 | IGSF21 | immunoglobin superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:28246] | 11008 | 0.000 | 0.3783 | No |
| 49 | MS4A7 | membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378] | 11155 | 0.000 | 0.3744 | No |
| 50 | PRAM1 | PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091] | 11515 | 0.000 | 0.3647 | No |
| 51 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 11592 | 0.000 | 0.3626 | No |
| 52 | S100Z | S100 calcium binding protein Z [Source:HGNC Symbol;Acc:HGNC:30367] | 11777 | 0.000 | 0.3576 | No |
| 53 | CLNK | cytokine dependent hematopoietic cell linker [Source:HGNC Symbol;Acc:HGNC:17438] | 11779 | 0.000 | 0.3576 | No |
| 54 | SIGLEC16 | sialic acid binding Ig like lectin 16 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:24851] | 11991 | 0.000 | 0.3519 | No |
| 55 | CSF2RA | colony stimulating factor 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2435] | 12074 | 0.000 | 0.3497 | No |
| 56 | AGR2 | anterior gradient 2, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:328] | 12228 | 0.000 | 0.3456 | No |
| 57 | LINC00996 | long intergenic non-protein coding RNA 996 [Source:HGNC Symbol;Acc:HGNC:27800] | 12230 | 0.000 | 0.3455 | No |
| 58 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12459 | 0.000 | 0.3394 | No |
| 59 | LILRA5 | leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309] | 13473 | 0.000 | 0.3120 | No |
| 60 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13477 | 0.000 | 0.3119 | No |
| 61 | LILRB2 | leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606] | 13478 | 0.000 | 0.3119 | No |
| 62 | LILRB3 | leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607] | 13479 | 0.000 | 0.3119 | No |
| 63 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13480 | 0.000 | 0.3119 | No |
| 64 | LILRB5 | leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609] | 13481 | 0.000 | 0.3119 | No |
| 65 | MEGF11 | multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635] | 14406 | 0.000 | 0.2869 | No |
| 66 | EBI3 | Epstein-Barr virus induced 3 [Source:HGNC Symbol;Acc:HGNC:3129] | 15119 | 0.000 | 0.2676 | No |
| 67 | ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:3357] | 15670 | 0.000 | 0.2527 | No |
| 68 | CD300LF | CD300 molecule like family member f [Source:HGNC Symbol;Acc:HGNC:29883] | 15828 | 0.000 | 0.2485 | No |
| 69 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15886 | 0.000 | 0.2469 | No |
| 70 | NEXMIF | neurite extension and migration factor [Source:HGNC Symbol;Acc:HGNC:29433] | 16056 | 0.000 | 0.2424 | No |
| 71 | TIMD4 | T cell immunoglobulin and mucin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25132] | 16257 | 0.000 | 0.2370 | No |
| 72 | TMEM63C | transmembrane protein 63C [Source:HGNC Symbol;Acc:HGNC:23787] | 18334 | 0.000 | 0.1808 | No |
| 73 | RN7SL138P | RNA, 7SL, cytoplasmic 138, pseudogene [Source:HGNC Symbol;Acc:HGNC:46154] | 18449 | 0.000 | 0.1777 | No |
| 74 | MRO | maestro [Source:HGNC Symbol;Acc:HGNC:24121] | 19141 | 0.000 | 0.1590 | No |
| 75 | MERTK | MER proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7027] | 20737 | 0.000 | 0.1159 | No |
| 76 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 20820 | 0.000 | 0.1137 | No |
| 77 | CD163L1 | CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375] | 21138 | 0.000 | 0.1051 | No |
| 78 | SIGLEC7 | sialic acid binding Ig like lectin 7 [Source:HGNC Symbol;Acc:HGNC:10876] | 21299 | 0.000 | 0.1008 | No |
| 79 | NRIR | negative regulator of interferon response [Source:HGNC Symbol;Acc:HGNC:51269] | 21365 | 0.000 | 0.0990 | No |
| 80 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 21551 | 0.000 | 0.0940 | No |
| 81 | EYA2 | EYA transcriptional coactivator and phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3520] | 21607 | 0.000 | 0.0925 | No |
| 82 | NCKAP5 | NCK associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29847] | 21621 | 0.000 | 0.0922 | No |
| 83 | PDCD1LG2 | programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] | 22932 | 0.000 | 0.0567 | No |
| 84 | CCDC170 | coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177] | 23381 | 0.000 | 0.0446 | No |
| 85 | MS4A4E | membrane spanning 4-domains A4E [Source:HGNC Symbol;Acc:HGNC:14284] | 23427 | 0.000 | 0.0434 | No |
| 86 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 23433 | 0.000 | 0.0432 | No |
| 87 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 23439 | 0.000 | 0.0431 | No |
| 88 | SPIC | Spi-C transcription factor [Source:HGNC Symbol;Acc:HGNC:29549] | 23741 | 0.000 | 0.0350 | No |
| 89 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 24200 | 0.000 | 0.0226 | No |
| 90 | OSCAR | osteoclast associated Ig-like receptor [Source:HGNC Symbol;Acc:HGNC:29960] | 24479 | 0.000 | 0.0151 | No |
| 91 | SIRPB2 | signal regulatory protein beta 2 [Source:HGNC Symbol;Acc:HGNC:16247] | 24497 | 0.000 | 0.0146 | No |
| 92 | RUFY4 | RUN and FYVE domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24804] | 24943 | 0.000 | 0.0026 | No |
| 93 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 24948 | 0.000 | 0.0024 | No |
| 94 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 27462 | 0.000 | -0.0655 | No |
| 95 | DSCAM-IT1 | DSCAM intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41327] | 27747 | 0.000 | -0.0732 | No |
| 96 | CLEC9A | C-type lectin domain containing 9A [Source:HGNC Symbol;Acc:HGNC:26705] | 28130 | 0.000 | -0.0836 | No |
| 97 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 28224 | 0.000 | -0.0861 | No |
| 98 | DSCAM | DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039] | 28476 | 0.000 | -0.0929 | No |
| 99 | KCNK13 | potassium two pore domain channel subfamily K member 13 [Source:HGNC Symbol;Acc:HGNC:6275] | 28661 | -0.037 | -0.0975 | No |
| 100 | LRRK1 | leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608] | 29454 | -0.229 | -0.1170 | No |
| 101 | MKNK1 | MAPK interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110] | 29609 | -0.265 | -0.1189 | No |
| 102 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 29705 | -0.292 | -0.1190 | No |
| 103 | TRPV4 | transient receptor potential cation channel subfamily V member 4 [Source:HGNC Symbol;Acc:HGNC:18083] | 29973 | -0.346 | -0.1233 | No |
| 104 | TRIM36 | tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280] | 30197 | -0.406 | -0.1259 | No |
| 105 | RAB39A | RAB39A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16521] | 30451 | -0.479 | -0.1287 | No |
| 106 | IGSF6 | immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953] | 30641 | -0.523 | -0.1294 | No |
| 107 | THEMIS2 | thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] | 30793 | -0.565 | -0.1287 | No |
| 108 | MCOLN1 | mucolipin 1 [Source:HGNC Symbol;Acc:HGNC:13356] | 31730 | -0.813 | -0.1471 | No |
| 109 | SIRPB1 | signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928] | 31909 | -0.876 | -0.1445 | No |
| 110 | DMXL2 | Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938] | 32034 | -0.922 | -0.1400 | No |
| 111 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase [Source:HGNC Symbol;Acc:HGNC:23015] | 32255 | -1.006 | -0.1375 | No |
| 112 | CD274 | CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635] | 32832 | -1.192 | -0.1430 | No |
| 113 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 32892 | -1.216 | -0.1343 | No |
| 114 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 33130 | -1.303 | -0.1296 | No |
| 115 | ADAP2 | ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487] | 33179 | -1.324 | -0.1197 | No |
| 116 | ZNF710 | zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352] | 33396 | -1.419 | -0.1135 | No |
| 117 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 33584 | -1.451 | -0.1063 | No |
| 118 | CDS1 | CDP-diacylglycerol synthase 1 [Source:HGNC Symbol;Acc:HGNC:1800] | 33591 | -1.451 | -0.0942 | No |
| 119 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 33602 | -1.451 | -0.0822 | No |
| 120 | HK3 | hexokinase 3 [Source:HGNC Symbol;Acc:HGNC:4925] | 34092 | -1.663 | -0.0813 | No |
| 121 | PPARG | peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] | 35221 | -2.316 | -0.0922 | No |
| 122 | WWP1 | WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:17004] | 35627 | -2.587 | -0.0812 | No |
| 123 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 35698 | -2.637 | -0.0608 | No |
| 124 | ALMS1P1 | ALMS1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:29586] | 36261 | -3.196 | -0.0489 | No |
| 125 | FLVCR2 | FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105] | 36798 | -4.003 | -0.0295 | No |
| 126 | SLC8A1 | solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068] | 36969 | -4.415 | 0.0033 | No |
