Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ZHONG_PFC_C2_UNKNOWN_NPC |
| Enrichment Score (ES) | -0.8225476 |
| Normalized Enrichment Score (NES) | -1.6909673 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.2874251E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2837 | 0.990 | -0.0688 | No |
| 2 | CNOT7 | CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101] | 3502 | 0.735 | -0.0809 | No |
| 3 | FAM83D | family with sequence similarity 83 member D [Source:HGNC Symbol;Acc:HGNC:16122] | 5418 | 0.239 | -0.1308 | No |
| 4 | CALB2 | calbindin 2 [Source:HGNC Symbol;Acc:HGNC:1435] | 8882 | 0.000 | -0.2243 | No |
| 5 | AC091057.1 | OTU deubiquitinase 7A pseudogene [Source:NCBI gene (formerly Entrezgene);Acc:100288637] | 12827 | 0.000 | -0.3309 | No |
| 6 | NDST4 | N-deacetylase and N-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:20779] | 13568 | 0.000 | -0.3509 | No |
| 7 | AMBN | ameloblastin [Source:HGNC Symbol;Acc:HGNC:452] | 21767 | 0.000 | -0.5723 | No |
| 8 | MFAP2 | microfibril associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033] | 22854 | 0.000 | -0.6017 | No |
| 9 | ZNF649 | zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741] | 26418 | 0.000 | -0.6979 | No |
| 10 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 28540 | -0.006 | -0.7552 | No |
| 11 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 28642 | -0.032 | -0.7577 | No |
| 12 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 28717 | -0.052 | -0.7593 | No |
| 13 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30002 | -0.356 | -0.7911 | No |
| 14 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 30165 | -0.400 | -0.7923 | No |
| 15 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 30301 | -0.433 | -0.7926 | No |
| 16 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 31183 | -0.669 | -0.8111 | No |
| 17 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31219 | -0.678 | -0.8066 | No |
| 18 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 31388 | -0.729 | -0.8054 | No |
| 19 | ARHGAP11A | Rho GTPase activating protein 11A [Source:HGNC Symbol;Acc:HGNC:15783] | 31643 | -0.782 | -0.8061 | No |
| 20 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 32254 | -1.006 | -0.8146 | Yes |
| 21 | CKAP2L | cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877] | 32271 | -1.013 | -0.8070 | Yes |
| 22 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 32360 | -1.030 | -0.8012 | Yes |
| 23 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 32370 | -1.033 | -0.7933 | Yes |
| 24 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 32541 | -1.098 | -0.7892 | Yes |
| 25 | TRIM59 | tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834] | 32585 | -1.113 | -0.7815 | Yes |
| 26 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 32716 | -1.154 | -0.7759 | Yes |
| 27 | REEP4 | receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176] | 32827 | -1.191 | -0.7694 | Yes |
| 28 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 33083 | -1.285 | -0.7661 | Yes |
| 29 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33194 | -1.331 | -0.7586 | Yes |
| 30 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 33203 | -1.334 | -0.7482 | Yes |
| 31 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 33207 | -1.335 | -0.7377 | Yes |
| 32 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33324 | -1.384 | -0.7299 | Yes |
| 33 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 33571 | -1.451 | -0.7250 | Yes |
| 34 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 33678 | -1.467 | -0.7163 | Yes |
| 35 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 33722 | -1.484 | -0.7057 | Yes |
| 36 | PIF1 | PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220] | 33731 | -1.487 | -0.6941 | Yes |
| 37 | LDHA | lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535] | 33841 | -1.535 | -0.6849 | Yes |
| 38 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 33895 | -1.555 | -0.6740 | Yes |
| 39 | RANGAP1 | Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854] | 33988 | -1.610 | -0.6638 | Yes |
| 40 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 33991 | -1.612 | -0.6510 | Yes |
| 41 | DNALI1 | dynein axonemal light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:14353] | 34158 | -1.693 | -0.6421 | Yes |
| 42 | MIS18BP1 | MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190] | 34184 | -1.710 | -0.6293 | Yes |
| 43 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34210 | -1.718 | -0.6163 | Yes |
| 44 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34312 | -1.770 | -0.6050 | Yes |
| 45 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 34343 | -1.784 | -0.5917 | Yes |
| 46 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 34662 | -1.944 | -0.5849 | Yes |
| 47 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 34865 | -2.088 | -0.5738 | Yes |
| 48 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 34879 | -2.099 | -0.5576 | Yes |
| 49 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 35002 | -2.171 | -0.5437 | Yes |
| 50 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 35069 | -2.220 | -0.5278 | Yes |
| 51 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35078 | -2.229 | -0.5104 | Yes |
| 52 | CIT | citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985] | 35154 | -2.290 | -0.4943 | Yes |
| 53 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35185 | -2.308 | -0.4768 | Yes |
| 54 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35370 | -2.370 | -0.4630 | Yes |
| 55 | NDE1 | nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619] | 35392 | -2.388 | -0.4447 | Yes |
| 56 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 35466 | -2.446 | -0.4273 | Yes |
| 57 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35576 | -2.541 | -0.4101 | Yes |
| 58 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 35581 | -2.547 | -0.3900 | Yes |
| 59 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35611 | -2.573 | -0.3704 | Yes |
| 60 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35643 | -2.607 | -0.3506 | Yes |
| 61 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 35708 | -2.647 | -0.3314 | Yes |
| 62 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 35725 | -2.658 | -0.3108 | Yes |
| 63 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 35809 | -2.746 | -0.2913 | Yes |
| 64 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 35837 | -2.768 | -0.2701 | Yes |
| 65 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35848 | -2.786 | -0.2483 | Yes |
| 66 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35850 | -2.788 | -0.2262 | Yes |
| 67 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 35873 | -2.813 | -0.2045 | Yes |
| 68 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35994 | -2.919 | -0.1846 | Yes |
| 69 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36053 | -2.978 | -0.1626 | Yes |
| 70 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 36078 | -3.003 | -0.1395 | Yes |
| 71 | PHF19 | PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566] | 36096 | -3.032 | -0.1159 | Yes |
| 72 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 36126 | -3.073 | -0.0924 | Yes |
| 73 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36311 | -3.256 | -0.0715 | Yes |
| 74 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 36395 | -3.379 | -0.0470 | Yes |
| 75 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36775 | -3.954 | -0.0259 | Yes |
| 76 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 36942 | -4.347 | 0.0040 | Yes |
