Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.52298427 |
| Normalized Enrichment Score (NES) | 1.2100343 |
| Nominal p-value | 0.12605043 |
| FDR q-value | 0.13809325 |
| FWER p-Value | 0.394 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 51 | 4.691 | 0.0635 | Yes |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 125 | 4.243 | 0.1203 | Yes |
| 3 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 875 | 2.329 | 0.1323 | Yes |
| 4 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 1051 | 2.085 | 0.1564 | Yes |
| 5 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 1202 | 1.890 | 0.1785 | Yes |
| 6 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 1207 | 1.887 | 0.2045 | Yes |
| 7 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 1367 | 1.850 | 0.2258 | Yes |
| 8 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 1369 | 1.849 | 0.2514 | Yes |
| 9 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 1451 | 1.743 | 0.2733 | Yes |
| 10 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 1465 | 1.734 | 0.2969 | Yes |
| 11 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 1713 | 1.547 | 0.3117 | Yes |
| 12 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 1718 | 1.541 | 0.3329 | Yes |
| 13 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1903 | 1.419 | 0.3475 | Yes |
| 14 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 1979 | 1.370 | 0.3645 | Yes |
| 15 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 2313 | 1.216 | 0.3723 | Yes |
| 16 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 2567 | 1.103 | 0.3807 | Yes |
| 17 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 2664 | 1.060 | 0.3928 | Yes |
| 18 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 2685 | 1.053 | 0.4069 | Yes |
| 19 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 2909 | 0.954 | 0.4140 | Yes |
| 20 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 3108 | 0.879 | 0.4208 | Yes |
| 21 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 3116 | 0.875 | 0.4328 | Yes |
| 22 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 3164 | 0.855 | 0.4433 | Yes |
| 23 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 3261 | 0.818 | 0.4521 | Yes |
| 24 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 3265 | 0.817 | 0.4633 | Yes |
| 25 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 3292 | 0.803 | 0.4737 | Yes |
| 26 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 3315 | 0.794 | 0.4841 | Yes |
| 27 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 3414 | 0.768 | 0.4921 | Yes |
| 28 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 3516 | 0.729 | 0.4994 | Yes |
| 29 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 3633 | 0.693 | 0.5059 | Yes |
| 30 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 3732 | 0.662 | 0.5124 | Yes |
| 31 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 3918 | 0.600 | 0.5157 | Yes |
| 32 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 4342 | 0.477 | 0.5109 | Yes |
| 33 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 4355 | 0.476 | 0.5171 | Yes |
| 34 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 4386 | 0.469 | 0.5228 | Yes |
| 35 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 4590 | 0.409 | 0.5230 | Yes |
| 36 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 5156 | 0.240 | 0.5110 | No |
| 37 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 5718 | 0.186 | 0.4985 | No |
| 38 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 5808 | 0.158 | 0.4982 | No |
| 39 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 12345 | 0.000 | 0.3218 | No |
| 40 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 29107 | -0.149 | -0.1288 | No |
| 41 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 29778 | -0.308 | -0.1426 | No |
| 42 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 30032 | -0.361 | -0.1444 | No |
| 43 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 30210 | -0.410 | -0.1435 | No |
| 44 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 31650 | -0.783 | -0.1716 | No |
| 45 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 32031 | -0.921 | -0.1691 | No |
| 46 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 32037 | -0.922 | -0.1565 | No |
| 47 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 32569 | -1.106 | -0.1555 | No |
| 48 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32981 | -1.249 | -0.1493 | No |
| 49 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 33017 | -1.262 | -0.1328 | No |
| 50 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 33039 | -1.269 | -0.1158 | No |
| 51 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 33350 | -1.397 | -0.1048 | No |
| 52 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 33442 | -1.442 | -0.0873 | No |
| 53 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 33895 | -1.555 | -0.0780 | No |
| 54 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34155 | -1.691 | -0.0616 | No |
| 55 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 34909 | -2.119 | -0.0526 | No |
| 56 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35037 | -2.200 | -0.0256 | No |
| 57 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 35322 | -2.326 | -0.0011 | No |
| 58 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36526 | -3.528 | 0.0152 | No |
