Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_NOTCH_SIGNALING |
| Enrichment Score (ES) | 0.3977445 |
| Normalized Enrichment Score (NES) | 0.8200444 |
| Nominal p-value | 0.8060837 |
| FDR q-value | 0.952636 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NOTCH1 | notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881] | 44 | 4.783 | 0.1113 | Yes |
| 2 | DTX1 | deltex E3 ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:3060] | 302 | 3.512 | 0.1869 | Yes |
| 3 | FZD5 | frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043] | 525 | 2.879 | 0.2486 | Yes |
| 4 | DTX2 | deltex E3 ubiquitin ligase 2 [Source:HGNC Symbol;Acc:HGNC:15973] | 540 | 2.850 | 0.3152 | Yes |
| 5 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 1041 | 2.096 | 0.3510 | Yes |
| 6 | DLL1 | delta like canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2908] | 1344 | 1.876 | 0.3870 | Yes |
| 7 | DTX4 | deltex E3 ubiquitin ligase 4 [Source:HGNC Symbol;Acc:HGNC:29151] | 2081 | 1.303 | 0.3977 | Yes |
| 8 | PSENEN | presenilin enhancer, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:30100] | 3819 | 0.636 | 0.3658 | No |
| 9 | FBXW11 | F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:HGNC:13607] | 4113 | 0.544 | 0.3707 | No |
| 10 | APH1A | aph-1 homolog A, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:29509] | 4643 | 0.394 | 0.3657 | No |
| 11 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 4697 | 0.376 | 0.3731 | No |
| 12 | SKP1 | S-phase kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:10899] | 4698 | 0.376 | 0.3819 | No |
| 13 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7267 | 0.000 | 0.3127 | No |
| 14 | HEYL | hes related family bHLH transcription factor with YRPW motif like [Source:HGNC Symbol;Acc:HGNC:4882] | 7415 | 0.000 | 0.3087 | No |
| 15 | FZD1 | frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038] | 19304 | 0.000 | -0.0121 | No |
| 16 | WNT5A | Wnt family member 5A [Source:HGNC Symbol;Acc:HGNC:12784] | 21951 | 0.000 | -0.0835 | No |
| 17 | WNT2 | Wnt family member 2 [Source:HGNC Symbol;Acc:HGNC:12780] | 22322 | 0.000 | -0.0935 | No |
| 18 | NOTCH3 | notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883] | 24665 | 0.000 | -0.1567 | No |
| 19 | NOTCH2 | notch receptor 2 [Source:HGNC Symbol;Acc:HGNC:7882] | 28902 | -0.097 | -0.2687 | No |
| 20 | CUL1 | cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551] | 30269 | -0.424 | -0.2956 | No |
| 21 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 30580 | -0.507 | -0.2921 | No |
| 22 | ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080] | 30599 | -0.512 | -0.2805 | No |
| 23 | TCF7L2 | transcription factor 7 like 2 [Source:HGNC Symbol;Acc:HGNC:11641] | 30866 | -0.584 | -0.2740 | No |
| 24 | RBX1 | ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928] | 30923 | -0.595 | -0.2615 | No |
| 25 | PSEN2 | presenilin 2 [Source:HGNC Symbol;Acc:HGNC:9509] | 31973 | -0.904 | -0.2685 | No |
| 26 | KAT2A | lysine acetyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:4201] | 32818 | -1.188 | -0.2634 | No |
| 27 | PRKCA | protein kinase C alpha [Source:HGNC Symbol;Acc:HGNC:9393] | 32917 | -1.229 | -0.2371 | No |
| 28 | CCND1 | cyclin D1 [Source:HGNC Symbol;Acc:HGNC:1582] | 34096 | -1.664 | -0.2298 | No |
| 29 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 34686 | -1.954 | -0.1997 | No |
| 30 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 35571 | -2.538 | -0.1639 | No |
| 31 | FZD7 | frizzled class receptor 7 [Source:HGNC Symbol;Acc:HGNC:4045] | 36941 | -4.340 | -0.0988 | No |
| 32 | ARRB1 | arrestin beta 1 [Source:HGNC Symbol;Acc:HGNC:711] | 36953 | -4.373 | 0.0037 | No |
