Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.39977503 |
| Normalized Enrichment Score (NES) | 0.9076097 |
| Nominal p-value | 0.6491935 |
| FDR q-value | 0.86965394 |
| FWER p-Value | 0.998 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 260 | 3.642 | 0.0496 | Yes |
| 2 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 344 | 3.401 | 0.1001 | Yes |
| 3 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 347 | 3.370 | 0.1525 | Yes |
| 4 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 367 | 3.300 | 0.2032 | Yes |
| 5 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 497 | 2.945 | 0.2455 | Yes |
| 6 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 537 | 2.855 | 0.2888 | Yes |
| 7 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 882 | 2.319 | 0.3155 | Yes |
| 8 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1359 | 1.862 | 0.3316 | Yes |
| 9 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1731 | 1.535 | 0.3454 | Yes |
| 10 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1858 | 1.456 | 0.3646 | Yes |
| 11 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 2441 | 1.151 | 0.3668 | Yes |
| 12 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 2977 | 0.938 | 0.3669 | Yes |
| 13 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 3192 | 0.845 | 0.3743 | Yes |
| 14 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 3359 | 0.790 | 0.3821 | Yes |
| 15 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 3367 | 0.786 | 0.3941 | Yes |
| 16 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 3568 | 0.712 | 0.3998 | Yes |
| 17 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 3922 | 0.599 | 0.3995 | No |
| 18 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 4326 | 0.481 | 0.3961 | No |
| 19 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 4721 | 0.368 | 0.3912 | No |
| 20 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 4824 | 0.340 | 0.3938 | No |
| 21 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9518 | 0.000 | 0.2671 | No |
| 22 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 11981 | 0.000 | 0.2006 | No |
| 23 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 17805 | 0.000 | 0.0434 | No |
| 24 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17990 | 0.000 | 0.0384 | No |
| 25 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19117 | 0.000 | 0.0080 | No |
| 26 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 28014 | 0.000 | -0.2321 | No |
| 27 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29201 | -0.176 | -0.2614 | No |
| 28 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 29209 | -0.178 | -0.2588 | No |
| 29 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 29303 | -0.197 | -0.2583 | No |
| 30 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 30000 | -0.355 | -0.2716 | No |
| 31 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 30251 | -0.418 | -0.2718 | No |
| 32 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 30346 | -0.446 | -0.2674 | No |
| 33 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 30872 | -0.585 | -0.2725 | No |
| 34 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 31704 | -0.805 | -0.2825 | No |
| 35 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 31753 | -0.822 | -0.2710 | No |
| 36 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 31758 | -0.823 | -0.2583 | No |
| 37 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31861 | -0.859 | -0.2477 | No |
| 38 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 32253 | -1.006 | -0.2426 | No |
| 39 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 32467 | -1.069 | -0.2318 | No |
| 40 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 32640 | -1.130 | -0.2189 | No |
| 41 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 33024 | -1.264 | -0.2096 | No |
| 42 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 33904 | -1.561 | -0.2091 | No |
| 43 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 34129 | -1.675 | -0.1891 | No |
| 44 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35041 | -2.202 | -0.1795 | No |
| 45 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 35514 | -2.488 | -0.1535 | No |
| 46 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 35859 | -2.791 | -0.1195 | No |
| 47 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 35898 | -2.843 | -0.0763 | No |
| 48 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 36168 | -3.128 | -0.0350 | No |
| 49 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36720 | -3.854 | 0.0100 | No |
