Fig 1: Enrichment plot: CHR16Q13
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | CHR16Q13 |
| Enrichment Score (ES) | 0.5499465 |
| Normalized Enrichment Score (NES) | 1.1812761 |
| Nominal p-value | 0.16317992 |
| FDR q-value | 0.38498896 |
| FWER p-Value | 0.974 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NLRC5 | NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933] | 140 | 4.379 | 0.1282 | Yes |
| 2 | MT1G | metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] | 477 | 3.276 | 0.2179 | Yes |
| 3 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 639 | 2.890 | 0.3007 | Yes |
| 4 | MT1A | metallothionein 1A [Source:HGNC Symbol;Acc:HGNC:7393] | 897 | 2.494 | 0.3689 | Yes |
| 5 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 1085 | 2.182 | 0.4296 | Yes |
| 6 | MT1E | metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397] | 1323 | 2.004 | 0.4836 | Yes |
| 7 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 1786 | 1.556 | 0.5181 | Yes |
| 8 | OGFOD1 | 2-oxoglutarate and iron dependent oxygenase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25585] | 2114 | 1.350 | 0.5499 | Yes |
| 9 | MT1L | metallothionein 1L, pseudogene [Source:HGNC Symbol;Acc:HGNC:7404] | 4108 | 0.473 | 0.5104 | No |
| 10 | MT1H | metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400] | 4320 | 0.473 | 0.5190 | No |
| 11 | MT1B | metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394] | 4407 | 0.469 | 0.5308 | No |
| 12 | MT1M | metallothionein 1M [Source:HGNC Symbol;Acc:HGNC:14296] | 5192 | 0.215 | 0.5161 | No |
| 13 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 5364 | 0.169 | 0.5166 | No |
| 14 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 5712 | 0.078 | 0.5096 | No |
| 15 | AC040168.1 | novel transcript | 8209 | 0.000 | 0.4423 | No |
| 16 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 9587 | 0.000 | 0.4051 | No |
| 17 | DPPA2P4 | developmental pluripotency associated 2 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:44629] | 9620 | 0.000 | 0.4042 | No |
| 18 | PLLP | plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553] | 9782 | 0.000 | 0.3999 | No |
| 19 | DKFZP434H168 | uncharacterized LOC26077 [Source:NCBI gene (formerly Entrezgene);Acc:26077] | 10837 | 0.000 | 0.3714 | No |
| 20 | MT1DP | metallothionein 1D, pseudogene [Source:HGNC Symbol;Acc:HGNC:7396] | 15727 | 0.000 | 0.2395 | No |
| 21 | MT1CP | metallothionein 1C, pseudogene [Source:HGNC Symbol;Acc:HGNC:7395] | 15735 | 0.000 | 0.2393 | No |
| 22 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 15814 | 0.000 | 0.2372 | No |
| 23 | AC106779.1 | novel transcript, antisense to NUP93 | 16814 | 0.000 | 0.2103 | No |
| 24 | SLC12A3 | solute carrier family 12 member 3 [Source:HGNC Symbol;Acc:HGNC:10912] | 17544 | 0.000 | 0.1906 | No |
| 25 | MT4 | metallothionein 4 [Source:HGNC Symbol;Acc:HGNC:18705] | 19092 | 0.000 | 0.1488 | No |
| 26 | MT3 | metallothionein 3 [Source:HGNC Symbol;Acc:HGNC:7408] | 19093 | 0.000 | 0.1488 | No |
| 27 | MIR138-2 | microRNA 138-2 [Source:HGNC Symbol;Acc:HGNC:31525] | 20701 | 0.000 | 0.1055 | No |
| 28 | MIR3935 | microRNA 3935 [Source:HGNC Symbol;Acc:HGNC:38918] | 25564 | 0.000 | -0.0258 | No |
| 29 | GNAO1 | G protein subunit alpha o1 [Source:HGNC Symbol;Acc:HGNC:4389] | 28602 | -0.133 | -0.1037 | No |
| 30 | AMFR | autocrine motility factor receptor [Source:HGNC Symbol;Acc:HGNC:463] | 30988 | -0.765 | -0.1450 | No |
| 31 | NUDT21 | nudix hydrolase 21 [Source:HGNC Symbol;Acc:HGNC:13870] | 31738 | -1.003 | -0.1350 | No |
| 32 | NUP93 | nucleoporin 93 [Source:HGNC Symbol;Acc:HGNC:28958] | 32898 | -1.398 | -0.1241 | No |
| 33 | ARL2BP | ADP ribosylation factor like GTPase 2 binding protein [Source:HGNC Symbol;Acc:HGNC:17146] | 32995 | -1.447 | -0.0831 | No |
| 34 | MT1F | metallothionein 1F [Source:HGNC Symbol;Acc:HGNC:7398] | 34090 | -1.959 | -0.0536 | No |
| 35 | BBS2 | Bardet-Biedl syndrome 2 [Source:HGNC Symbol;Acc:HGNC:967] | 34171 | -2.008 | 0.0048 | No |
| 36 | CPNE2 | copine 2 [Source:HGNC Symbol;Acc:HGNC:2315] | 34962 | -2.455 | 0.0574 | No |
