Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN |
| Enrichment Score (ES) | 0.8486937 |
| Normalized Enrichment Score (NES) | 2.0819871 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0219 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 10 | 4.992 | 0.0438 | Yes |
| 3 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 15 | 4.978 | 0.0656 | Yes |
| 4 | ACOD1 | aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904] | 18 | 4.969 | 0.0874 | Yes |
| 5 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 23 | 4.958 | 0.1091 | Yes |
| 6 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 26 | 4.953 | 0.1309 | Yes |
| 7 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 64 | 4.795 | 0.1510 | Yes |
| 8 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 68 | 4.762 | 0.1719 | Yes |
| 9 | PHLDA1 | pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933] | 74 | 4.748 | 0.1927 | Yes |
| 10 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 87 | 4.663 | 0.2129 | Yes |
| 11 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 95 | 4.645 | 0.2331 | Yes |
| 12 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 107 | 4.599 | 0.2531 | Yes |
| 13 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 127 | 4.445 | 0.2722 | Yes |
| 14 | SOCS3 | suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391] | 135 | 4.408 | 0.2914 | Yes |
| 15 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 141 | 4.379 | 0.3105 | Yes |
| 16 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 152 | 4.332 | 0.3293 | Yes |
| 17 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 181 | 4.218 | 0.3472 | Yes |
| 18 | ADORA2B | adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264] | 190 | 4.165 | 0.3653 | Yes |
| 19 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986] | 198 | 4.130 | 0.3833 | Yes |
| 20 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 210 | 4.078 | 0.4010 | Yes |
| 21 | CD83 | CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703] | 223 | 4.055 | 0.4185 | Yes |
| 22 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 224 | 4.054 | 0.4363 | Yes |
| 23 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 225 | 4.052 | 0.4542 | Yes |
| 24 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 226 | 4.041 | 0.4720 | Yes |
| 25 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 259 | 3.897 | 0.4883 | Yes |
| 26 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 262 | 3.886 | 0.5053 | Yes |
| 27 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 265 | 3.877 | 0.5224 | Yes |
| 28 | PDLIM7 | PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958] | 277 | 3.842 | 0.5390 | Yes |
| 29 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 278 | 3.840 | 0.5559 | Yes |
| 30 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 326 | 3.705 | 0.5710 | Yes |
| 31 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 375 | 3.557 | 0.5853 | Yes |
| 32 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 377 | 3.549 | 0.6009 | Yes |
| 33 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 395 | 3.493 | 0.6159 | Yes |
| 34 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 404 | 3.447 | 0.6308 | Yes |
| 35 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 413 | 3.427 | 0.6457 | Yes |
| 36 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 486 | 3.252 | 0.6581 | Yes |
| 37 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 488 | 3.246 | 0.6723 | Yes |
| 38 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 508 | 3.206 | 0.6859 | Yes |
| 39 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 536 | 3.138 | 0.6990 | Yes |
| 40 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 543 | 3.130 | 0.7127 | Yes |
| 41 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 558 | 3.089 | 0.7259 | Yes |
| 42 | PCDH7 | protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659] | 595 | 2.997 | 0.7381 | Yes |
| 43 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 648 | 2.871 | 0.7494 | Yes |
| 44 | IKBKE | inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552] | 720 | 2.819 | 0.7599 | Yes |
| 45 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 733 | 2.785 | 0.7718 | Yes |
| 46 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 774 | 2.696 | 0.7826 | Yes |
| 47 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 786 | 2.676 | 0.7941 | Yes |
| 48 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 802 | 2.641 | 0.8053 | Yes |
| 49 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 864 | 2.531 | 0.8148 | Yes |
| 50 | SRPRA | SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307] | 945 | 2.413 | 0.8233 | Yes |
| 51 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 1035 | 2.264 | 0.8308 | Yes |
| 52 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 1085 | 2.182 | 0.8391 | Yes |
| 53 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1087 | 2.179 | 0.8487 | Yes |
| 54 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 1425 | 1.880 | 0.8479 | No |
| 55 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 1786 | 1.556 | 0.8450 | No |
| 56 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 2119 | 1.347 | 0.8420 | No |
| 57 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 2312 | 1.239 | 0.8422 | No |
| 58 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 2320 | 1.233 | 0.8475 | No |
| 59 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 2536 | 1.116 | 0.8466 | No |
| 60 | TSC22D1 | TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826] | 3022 | 0.874 | 0.8373 | No |
| 61 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 3053 | 0.854 | 0.8403 | No |
| 62 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 3452 | 0.700 | 0.8326 | No |
| 63 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 4793 | 0.350 | 0.7979 | No |
| 64 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 5184 | 0.218 | 0.7884 | No |
| 65 | CDC42EP4 | CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147] | 5734 | 0.070 | 0.7738 | No |
| 66 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 5774 | 0.056 | 0.7730 | No |
| 67 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6028 | 0.000 | 0.7662 | No |
| 68 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8563 | 0.000 | 0.6977 | No |
| 69 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13282 | 0.000 | 0.5702 | No |
| 70 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19493 | 0.000 | 0.4025 | No |
| 71 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 22732 | 0.000 | 0.3150 | No |
| 72 | UBC | ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468] | 28528 | -0.112 | 0.1589 | No |
| 73 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 30795 | -0.709 | 0.1008 | No |
| 74 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 32523 | -1.236 | 0.0596 | No |
| 75 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 33261 | -1.559 | 0.0465 | No |
| 76 | PKM | pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] | 33530 | -1.682 | 0.0467 | No |
| 77 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 33922 | -1.880 | 0.0444 | No |
| 78 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 34573 | -2.217 | 0.0366 | No |
| 79 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35184 | -2.627 | 0.0317 | No |
| 80 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 36921 | -4.491 | 0.0046 | No |
