Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GHANDHI_BYSTANDER_IRRADIATION_UP |
| Enrichment Score (ES) | 0.8011433 |
| Normalized Enrichment Score (NES) | 1.9930898 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.977818E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0390 | Yes |
| 2 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 16 | 4.972 | 0.0775 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 26 | 4.953 | 0.1159 | Yes |
| 4 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 28 | 4.948 | 0.1545 | Yes |
| 5 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 38 | 4.922 | 0.1927 | Yes |
| 6 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 52 | 4.845 | 0.2302 | Yes |
| 7 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 68 | 4.762 | 0.2670 | Yes |
| 8 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 69 | 4.761 | 0.3042 | Yes |
| 9 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.3409 | Yes |
| 10 | CREB5 | cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844] | 121 | 4.493 | 0.3749 | Yes |
| 11 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 130 | 4.430 | 0.4093 | Yes |
| 12 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 194 | 4.158 | 0.4401 | Yes |
| 13 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 272 | 3.860 | 0.4681 | Yes |
| 14 | OSGIN2 | oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355] | 282 | 3.830 | 0.4978 | Yes |
| 15 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 358 | 3.581 | 0.5238 | Yes |
| 16 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 375 | 3.557 | 0.5511 | Yes |
| 17 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 427 | 3.359 | 0.5760 | Yes |
| 18 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 428 | 3.354 | 0.6022 | Yes |
| 19 | MT1G | metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] | 477 | 3.276 | 0.6265 | Yes |
| 20 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 567 | 3.066 | 0.6480 | Yes |
| 21 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 914 | 2.461 | 0.6579 | Yes |
| 22 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 1085 | 2.182 | 0.6704 | Yes |
| 23 | ZC3H12C | zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362] | 1132 | 2.130 | 0.6858 | Yes |
| 24 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 1146 | 2.099 | 0.7018 | Yes |
| 25 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1296 | 2.040 | 0.7137 | Yes |
| 26 | MT1E | metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397] | 1323 | 2.004 | 0.7287 | Yes |
| 27 | TUT7 | terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817] | 1392 | 1.922 | 0.7418 | Yes |
| 28 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 1587 | 1.726 | 0.7501 | Yes |
| 29 | SLC39A14 | solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858] | 1613 | 1.705 | 0.7627 | Yes |
| 30 | PLEK2 | pleckstrin 2 [Source:HGNC Symbol;Acc:HGNC:19238] | 1660 | 1.682 | 0.7746 | Yes |
| 31 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 1667 | 1.673 | 0.7875 | Yes |
| 32 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1865 | 1.496 | 0.7939 | Yes |
| 33 | NAMPTP1 | nicotinamide phosphoribosyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17633] | 2239 | 1.281 | 0.7938 | Yes |
| 34 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 2325 | 1.231 | 0.8011 | Yes |
| 35 | C9orf72 | C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337] | 2840 | 0.959 | 0.7947 | No |
| 36 | DNAJB4 | DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886] | 3378 | 0.727 | 0.7859 | No |
| 37 | RGS9 | regulator of G protein signaling 9 [Source:HGNC Symbol;Acc:HGNC:10004] | 3582 | 0.647 | 0.7855 | No |
| 38 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 3886 | 0.528 | 0.7814 | No |
| 39 | ATP6V1C1 | ATPase H+ transporting V1 subunit C1 [Source:HGNC Symbol;Acc:HGNC:856] | 3941 | 0.510 | 0.7839 | No |
| 40 | PPP4R3B | protein phosphatase 4 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:29267] | 3960 | 0.503 | 0.7874 | No |
| 41 | GADD45G | growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] | 4319 | 0.473 | 0.7814 | No |
| 42 | MT1H | metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400] | 4320 | 0.473 | 0.7851 | No |
| 43 | SLC39A8 | solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] | 4390 | 0.473 | 0.7869 | No |
| 44 | MT1B | metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394] | 4407 | 0.469 | 0.7902 | No |
| 45 | ZSWIM8 | zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528] | 4668 | 0.384 | 0.7862 | No |
| 46 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4726 | 0.369 | 0.7875 | No |
| 47 | PHEX | phosphate regulating endopeptidase homolog X-linked [Source:HGNC Symbol;Acc:HGNC:8918] | 5417 | 0.153 | 0.7700 | No |
| 48 | MCTP1 | multiple C2 and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26183] | 7630 | 0.000 | 0.7103 | No |
| 49 | MCTP2 | multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636] | 7643 | 0.000 | 0.7099 | No |
| 50 | POPDC3 | popeye domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17649] | 8415 | 0.000 | 0.6891 | No |
| 51 | SLC16A6P1 | SLC16A6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48932] | 10167 | 0.000 | 0.6418 | No |
| 52 | B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684] | 10497 | 0.000 | 0.6329 | No |
| 53 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 11626 | 0.000 | 0.6024 | No |
| 54 | PTGFR | prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600] | 11642 | 0.000 | 0.6020 | No |
| 55 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13678 | 0.000 | 0.5470 | No |
| 56 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208] | 14273 | 0.000 | 0.5310 | No |
| 57 | EPB41L4B | erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818] | 14947 | 0.000 | 0.5128 | No |
| 58 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15720 | 0.000 | 0.4919 | No |
| 59 | PRR7-AS1 | PRR7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27961] | 17059 | 0.000 | 0.4558 | No |
| 60 | SRSF12 | serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] | 17489 | 0.000 | 0.4442 | No |
| 61 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19128 | 0.000 | 0.3999 | No |
| 62 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 19132 | 0.000 | 0.3998 | No |
| 63 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19482 | 0.000 | 0.3904 | No |
| 64 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19491 | 0.000 | 0.3902 | No |
| 65 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19493 | 0.000 | 0.3902 | No |
| 66 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19494 | 0.000 | 0.3902 | No |
| 67 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19496 | 0.000 | 0.3901 | No |
| 68 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 20641 | 0.000 | 0.3592 | No |
| 69 | C2CD4B | C2 calcium dependent domain containing 4B [Source:HGNC Symbol;Acc:HGNC:33628] | 21616 | 0.000 | 0.3329 | No |
| 70 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 22443 | 0.000 | 0.3106 | No |
| 71 | TESC | tescalcin [Source:HGNC Symbol;Acc:HGNC:26065] | 25220 | 0.000 | 0.2356 | No |
| 72 | IFNE | interferon epsilon [Source:HGNC Symbol;Acc:HGNC:18163] | 25536 | 0.000 | 0.2271 | No |
| 73 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 26886 | 0.000 | 0.1906 | No |
| 74 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 26962 | 0.000 | 0.1886 | No |
| 75 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 28011 | 0.000 | 0.1603 | No |
| 76 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 28887 | -0.203 | 0.1382 | No |
| 77 | SLC16A6 | solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927] | 29284 | -0.308 | 0.1299 | No |
| 78 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 29755 | -0.431 | 0.1206 | No |
| 79 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 29814 | -0.444 | 0.1225 | No |
| 80 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 32204 | -1.178 | 0.0671 | No |
| 81 | RNF128 | ring finger protein 128 [Source:HGNC Symbol;Acc:HGNC:21153] | 34217 | -2.034 | 0.0287 | No |
| 82 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 34993 | -2.486 | 0.0271 | No |
| 83 | LRRC8B | leucine rich repeat containing 8 VRAC subunit B [Source:HGNC Symbol;Acc:HGNC:30692] | 36414 | -3.776 | 0.0183 | No |
