Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8696266 |
| Normalized Enrichment Score (NES) | -1.6747706 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0012714028 |
| FWER p-Value | 0.027 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.1527 | No |
| 2 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 26970 | 0.000 | -0.7275 | No |
| 3 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8619 | Yes |
| 4 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32455 | -1.232 | -0.8599 | Yes |
| 5 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 32607 | -1.270 | -0.8558 | Yes |
| 6 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32691 | -1.316 | -0.8496 | Yes |
| 7 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.8559 | Yes |
| 8 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8457 | Yes |
| 9 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 33683 | -1.743 | -0.8447 | Yes |
| 10 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8363 | Yes |
| 11 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.8359 | Yes |
| 12 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 34861 | -2.396 | -0.8360 | Yes |
| 13 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 34863 | -2.398 | -0.8205 | Yes |
| 14 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34953 | -2.448 | -0.8072 | Yes |
| 15 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.7939 | Yes |
| 16 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.7779 | Yes |
| 17 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.7629 | Yes |
| 18 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35154 | -2.602 | -0.7462 | Yes |
| 19 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35157 | -2.606 | -0.7294 | Yes |
| 20 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.7127 | Yes |
| 21 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35361 | -2.726 | -0.7005 | Yes |
| 22 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35673 | -3.046 | -0.6893 | Yes |
| 23 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 35913 | -3.275 | -0.6746 | Yes |
| 24 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 36019 | -3.358 | -0.6558 | Yes |
| 25 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.6346 | Yes |
| 26 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.6132 | Yes |
| 27 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36057 | -3.385 | -0.5914 | Yes |
| 28 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36157 | -3.491 | -0.5716 | Yes |
| 29 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36172 | -3.498 | -0.5494 | Yes |
| 30 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36288 | -3.614 | -0.5293 | Yes |
| 31 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36304 | -3.637 | -0.5062 | Yes |
| 32 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36324 | -3.663 | -0.4831 | Yes |
| 33 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36371 | -3.711 | -0.4605 | Yes |
| 34 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36388 | -3.732 | -0.4368 | Yes |
| 35 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36406 | -3.765 | -0.4130 | Yes |
| 36 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36440 | -3.801 | -0.3894 | Yes |
| 37 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.3658 | Yes |
| 38 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36519 | -3.907 | -0.3415 | Yes |
| 39 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.3174 | Yes |
| 40 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36582 | -3.982 | -0.2918 | Yes |
| 41 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.2662 | Yes |
| 42 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.2405 | Yes |
| 43 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36685 | -4.099 | -0.2166 | Yes |
| 44 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.1906 | Yes |
| 45 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36735 | -4.169 | -0.1644 | Yes |
| 46 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.1384 | Yes |
| 47 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36819 | -4.299 | -0.1115 | Yes |
| 48 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.0840 | Yes |
| 49 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36887 | -4.439 | -0.0567 | Yes |
| 50 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37007 | -4.708 | -0.0295 | Yes |
| 51 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 37062 | -4.928 | 0.0008 | Yes |
