Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KONG_E2F3_TARGETS |
| Enrichment Score (ES) | -0.8218036 |
| Normalized Enrichment Score (NES) | -1.6942809 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0012015281 |
| FWER p-Value | 0.017 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 515 | 3.193 | -0.0010 | No |
| 2 | NR1D1 | nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] | 1674 | 1.667 | -0.0255 | No |
| 3 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 1886 | 1.476 | -0.0253 | No |
| 4 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 2747 | 1.006 | -0.0445 | No |
| 5 | SRSF7 | serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789] | 3321 | 0.753 | -0.0569 | No |
| 6 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 3677 | 0.604 | -0.0640 | No |
| 7 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 3798 | 0.562 | -0.0650 | No |
| 8 | H4C15 | H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607] | 12476 | 0.000 | -0.2996 | No |
| 9 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16663 | 0.000 | -0.4127 | No |
| 10 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 16942 | 0.000 | -0.4202 | No |
| 11 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 19199 | 0.000 | -0.4812 | No |
| 12 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 20190 | 0.000 | -0.5080 | No |
| 13 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 21041 | 0.000 | -0.5310 | No |
| 14 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866] | 21128 | 0.000 | -0.5333 | No |
| 15 | PRL | prolactin [Source:HGNC Symbol;Acc:HGNC:9445] | 24800 | 0.000 | -0.6325 | No |
| 16 | PSORS1C2 | psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199] | 25490 | 0.000 | -0.6511 | No |
| 17 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 27718 | 0.000 | -0.7113 | No |
| 18 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 28954 | -0.222 | -0.7438 | No |
| 19 | FBXO45 | F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148] | 29117 | -0.259 | -0.7471 | No |
| 20 | RBBP8 | RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891] | 29740 | -0.427 | -0.7622 | No |
| 21 | MAPK8 | mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881] | 30472 | -0.612 | -0.7795 | No |
| 22 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759] | 31957 | -1.079 | -0.8153 | No |
| 23 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8142 | No |
| 24 | RPRD1B | regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209] | 32199 | -1.175 | -0.8124 | No |
| 25 | NUP50 | nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065] | 32509 | -1.233 | -0.8158 | No |
| 26 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 32733 | -1.333 | -0.8164 | Yes |
| 27 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 32737 | -1.335 | -0.8111 | Yes |
| 28 | FAM111A | family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725] | 32781 | -1.353 | -0.8068 | Yes |
| 29 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 33021 | -1.462 | -0.8073 | Yes |
| 30 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 33233 | -1.548 | -0.8068 | Yes |
| 31 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33291 | -1.571 | -0.8019 | Yes |
| 32 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 33618 | -1.730 | -0.8037 | Yes |
| 33 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8014 | Yes |
| 34 | CENPQ | centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347] | 34128 | -1.984 | -0.8021 | Yes |
| 35 | RBL1 | RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893] | 34208 | -2.028 | -0.7960 | Yes |
| 36 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34283 | -2.068 | -0.7897 | Yes |
| 37 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.7814 | Yes |
| 38 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 34680 | -2.278 | -0.7828 | Yes |
| 39 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 34852 | -2.390 | -0.7777 | Yes |
| 40 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 34863 | -2.398 | -0.7683 | Yes |
| 41 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 34889 | -2.412 | -0.7592 | Yes |
| 42 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.7537 | Yes |
| 43 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.7439 | Yes |
| 44 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.7350 | Yes |
| 45 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 35348 | -2.720 | -0.7293 | Yes |
| 46 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35361 | -2.726 | -0.7186 | Yes |
| 47 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35409 | -2.763 | -0.7087 | Yes |
| 48 | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794] | 35489 | -2.826 | -0.6994 | Yes |
| 49 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 35491 | -2.828 | -0.6880 | Yes |
| 50 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.6778 | Yes |
| 51 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35673 | -3.046 | -0.6689 | Yes |
| 52 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 35721 | -3.059 | -0.6577 | Yes |
| 53 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.6454 | Yes |
| 54 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.6356 | Yes |
| 55 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 35844 | -3.180 | -0.6229 | Yes |
| 56 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 35851 | -3.186 | -0.6101 | Yes |
| 57 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 35853 | -3.190 | -0.5973 | Yes |
| 58 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35958 | -3.323 | -0.5866 | Yes |
| 59 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36017 | -3.355 | -0.5746 | Yes |
| 60 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 36019 | -3.358 | -0.5610 | Yes |
| 61 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36027 | -3.367 | -0.5476 | Yes |
| 62 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.5346 | Yes |
| 63 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.5218 | Yes |
| 64 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36110 | -3.445 | -0.5082 | Yes |
| 65 | PSIP1 | PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527] | 36116 | -3.452 | -0.4944 | Yes |
| 66 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.4813 | Yes |
| 67 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36167 | -3.496 | -0.4674 | Yes |
| 68 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36172 | -3.498 | -0.4534 | Yes |
| 69 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 36189 | -3.522 | -0.4396 | Yes |
| 70 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36288 | -3.614 | -0.4276 | Yes |
| 71 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36324 | -3.663 | -0.4137 | Yes |
| 72 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.3997 | Yes |
| 73 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36388 | -3.732 | -0.3853 | Yes |
| 74 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36460 | -3.819 | -0.3718 | Yes |
| 75 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 36474 | -3.838 | -0.3566 | Yes |
| 76 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.3414 | Yes |
| 77 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.3262 | Yes |
| 78 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36519 | -3.907 | -0.3106 | Yes |
| 79 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.2959 | Yes |
| 80 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.2799 | Yes |
| 81 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 36584 | -3.986 | -0.2639 | Yes |
| 82 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.2479 | Yes |
| 83 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36591 | -3.999 | -0.2317 | Yes |
| 84 | CBX2 | chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552] | 36600 | -4.010 | -0.2157 | Yes |
| 85 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.1996 | Yes |
| 86 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36660 | -4.066 | -0.1845 | Yes |
| 87 | HLX | H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978] | 36663 | -4.073 | -0.1681 | Yes |
| 88 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.1517 | Yes |
| 89 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36735 | -4.169 | -0.1366 | Yes |
| 90 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36783 | -4.238 | -0.1207 | Yes |
| 91 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36795 | -4.256 | -0.1038 | Yes |
| 92 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.0873 | Yes |
| 93 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36883 | -4.431 | -0.0706 | Yes |
| 94 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36915 | -4.481 | -0.0533 | Yes |
| 95 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36994 | -4.675 | -0.0365 | Yes |
| 96 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37007 | -4.708 | -0.0177 | Yes |
| 97 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 37062 | -4.928 | 0.0008 | Yes |
