Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | REACTOME_FCGR_ACTIVATION |
| Enrichment Score (ES) | 0.9272325 |
| Normalized Enrichment Score (NES) | 2.2423146 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FCGR2A | Fc fragment of IgG receptor IIa [Source:HGNC Symbol;Acc:HGNC:3616] | 193 | 4.158 | 0.1987 | Yes |
| 2 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 534 | 3.141 | 0.3435 | Yes |
| 3 | FGR | FGR proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3697] | 579 | 3.036 | 0.4911 | Yes |
| 4 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 814 | 2.632 | 0.6139 | Yes |
| 5 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 870 | 2.517 | 0.7358 | Yes |
| 6 | CD247 | CD247 molecule [Source:HGNC Symbol;Acc:HGNC:1677] | 1798 | 1.546 | 0.7865 | Yes |
| 7 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 2403 | 1.186 | 0.8284 | Yes |
| 8 | FYN | FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037] | 2469 | 1.162 | 0.8836 | Yes |
| 9 | YES1 | YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12841] | 2702 | 1.018 | 0.9272 | Yes |
| 10 | IGHV2-70 | immunoglobulin heavy variable 2-70 [Source:HGNC Symbol;Acc:HGNC:5577] | 6113 | 0.000 | 0.8351 | No |
| 11 | IGHV1-69 | immunoglobulin heavy variable 1-69 [Source:HGNC Symbol;Acc:HGNC:5558] | 6938 | 0.000 | 0.8129 | No |
| 12 | IGHV1-46 | immunoglobulin heavy variable 1-46 [Source:HGNC Symbol;Acc:HGNC:5554] | 6968 | 0.000 | 0.8121 | No |
| 13 | IGLV7-43 | immunoglobulin lambda variable 7-43 [Source:HGNC Symbol;Acc:HGNC:5929] | 7624 | 0.000 | 0.7944 | No |
| 14 | IGKV2-28 | immunoglobulin kappa variable 2-28 [Source:HGNC Symbol;Acc:HGNC:5783] | 7634 | 0.000 | 0.7941 | No |
| 15 | IGKV2-30 | immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785] | 7644 | 0.000 | 0.7939 | No |
| 16 | IGHV3-7 | immunoglobulin heavy variable 3-7 [Source:HGNC Symbol;Acc:HGNC:5620] | 8874 | 0.000 | 0.7607 | No |
| 17 | IGHV4-59 | immunoglobulin heavy variable 4-59 [Source:HGNC Symbol;Acc:HGNC:5654] | 10928 | 0.000 | 0.7053 | No |
| 18 | IGHV4-34 | immunoglobulin heavy variable 4-34 [Source:HGNC Symbol;Acc:HGNC:5650] | 10942 | 0.000 | 0.7049 | No |
| 19 | IGHV4-39 | immunoglobulin heavy variable 4-39 [Source:HGNC Symbol;Acc:HGNC:5651] | 10943 | 0.000 | 0.7049 | No |
| 20 | FCGR3A | Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619] | 11234 | 0.000 | 0.6971 | No |
| 21 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 11262 | 0.000 | 0.6963 | No |
| 22 | IGLV3-19 | immunoglobulin lambda variable 3-19 [Source:HGNC Symbol;Acc:HGNC:5903] | 11518 | 0.000 | 0.6895 | No |
| 23 | IGLV3-25 | immunoglobulin lambda variable 3-25 [Source:HGNC Symbol;Acc:HGNC:5908] | 11522 | 0.000 | 0.6894 | No |
| 24 | IGLV3-27 | immunoglobulin lambda variable 3-27 [Source:HGNC Symbol;Acc:HGNC:5910] | 11524 | 0.000 | 0.6893 | No |
| 25 | IGLV3-21 | immunoglobulin lambda variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5905] | 11525 | 0.000 | 0.6893 | No |
| 26 | IGLV3-1 | immunoglobulin lambda variable 3-1 [Source:HGNC Symbol;Acc:HGNC:5896] | 12376 | 0.000 | 0.6664 | No |
| 27 | IGKV1-39 | immunoglobulin kappa variable 1-39 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5740] | 12382 | 0.000 | 0.6663 | No |
| 28 | IGKV1-33 | immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737] | 12392 | 0.000 | 0.6660 | No |
| 29 | IGKV1-16 | immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732] | 12411 | 0.000 | 0.6655 | No |
| 30 | IGKV1-17 | immunoglobulin kappa variable 1-17 [Source:HGNC Symbol;Acc:HGNC:5733] | 12412 | 0.000 | 0.6655 | No |
| 31 | IGKV1-12 | immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730] | 12413 | 0.000 | 0.6655 | No |
| 32 | IGKV2D-28 | immunoglobulin kappa variable 2D-28 [Source:HGNC Symbol;Acc:HGNC:5799] | 12544 | 0.000 | 0.6620 | No |
| 33 | IGKV2D-30 | immunoglobulin kappa variable 2D-30 [Source:HGNC Symbol;Acc:HGNC:5801] | 12553 | 0.000 | 0.6618 | No |
| 34 | IGKV2D-40 | immunoglobulin kappa variable 2D-40 [Source:HGNC Symbol;Acc:HGNC:5804] | 12557 | 0.000 | 0.6617 | No |
| 35 | IGKV5-2 | immunoglobulin kappa variable 5-2 [Source:HGNC Symbol;Acc:HGNC:5835] | 13797 | 0.000 | 0.6282 | No |
| 36 | IGLV2-8 | immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895] | 14874 | 0.000 | 0.5992 | No |
| 37 | IGLV2-11 | immunoglobulin lambda variable 2-11 [Source:HGNC Symbol;Acc:HGNC:5887] | 16125 | 0.000 | 0.5654 | No |
| 38 | IGLV2-14 | immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888] | 16126 | 0.000 | 0.5654 | No |
| 39 | IGLV2-23 | immunoglobulin lambda variable 2-23 [Source:HGNC Symbol;Acc:HGNC:5890] | 16133 | 0.000 | 0.5653 | No |
| 40 | IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) [Source:HGNC Symbol;Acc:HGNC:5528] | 17119 | 0.000 | 0.5387 | No |
| 41 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525] | 17122 | 0.000 | 0.5386 | No |
| 42 | IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526] | 17124 | 0.000 | 0.5386 | No |
| 43 | IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857] | 17708 | 0.000 | 0.5228 | No |
| 44 | IGLC2 | immunoglobulin lambda constant 2 [Source:HGNC Symbol;Acc:HGNC:5856] | 17712 | 0.000 | 0.5227 | No |
| 45 | IGHV3-23 | immunoglobulin heavy variable 3-23 [Source:HGNC Symbol;Acc:HGNC:5588] | 17989 | 0.000 | 0.5153 | No |
| 46 | IGHV3-30 | immunoglobulin heavy variable 3-30 [Source:HGNC Symbol;Acc:HGNC:5591] | 18007 | 0.000 | 0.5148 | No |
| 47 | IGHV3-33 | immunoglobulin heavy variable 3-33 [Source:HGNC Symbol;Acc:HGNC:5596] | 18010 | 0.000 | 0.5148 | No |
| 48 | IGHV3-11 | immunoglobulin heavy variable 3-11 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5580] | 18049 | 0.000 | 0.5137 | No |
| 49 | IGHV3-13 | immunoglobulin heavy variable 3-13 [Source:HGNC Symbol;Acc:HGNC:5581] | 18052 | 0.000 | 0.5137 | No |
| 50 | IGHV3-48 | immunoglobulin heavy variable 3-48 [Source:HGNC Symbol;Acc:HGNC:5606] | 18233 | 0.000 | 0.5088 | No |
| 51 | IGHV3-53 | immunoglobulin heavy variable 3-53 [Source:HGNC Symbol;Acc:HGNC:5610] | 18242 | 0.000 | 0.5086 | No |
| 52 | IGKV1-5 | immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741] | 18298 | 0.000 | 0.5071 | No |
| 53 | IGKV4-1 | immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834] | 19335 | 0.000 | 0.4791 | No |
| 54 | IGKV3D-20 | immunoglobulin kappa variable 3D-20 [Source:HGNC Symbol;Acc:HGNC:5825] | 20762 | 0.000 | 0.4406 | No |
| 55 | IGLV1-40 | immunoglobulin lambda variable 1-40 [Source:HGNC Symbol;Acc:HGNC:5877] | 21511 | 0.000 | 0.4204 | No |
| 56 | IGLV1-47 | immunoglobulin lambda variable 1-47 [Source:HGNC Symbol;Acc:HGNC:5880] | 21512 | 0.000 | 0.4204 | No |
| 57 | IGLV1-44 | immunoglobulin lambda variable 1-44 [Source:HGNC Symbol;Acc:HGNC:5879] | 21513 | 0.000 | 0.4204 | No |
| 58 | IGLV1-51 | immunoglobulin lambda variable 1-51 [Source:HGNC Symbol;Acc:HGNC:5882] | 21527 | 0.000 | 0.4201 | No |
| 59 | IGKV3-15 | immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816] | 22090 | 0.000 | 0.4049 | No |
| 60 | IGKV3-11 | immunoglobulin kappa variable 3-11 [Source:HGNC Symbol;Acc:HGNC:5815] | 22097 | 0.000 | 0.4047 | No |
| 61 | IGKV3-20 | immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817] | 22123 | 0.000 | 0.4041 | No |
| 62 | IGHV1-2 | immunoglobulin heavy variable 1-2 [Source:HGNC Symbol;Acc:HGNC:5550] | 24027 | 0.000 | 0.3527 | No |
| 63 | IGHV2-5 | immunoglobulin heavy variable 2-5 [Source:HGNC Symbol;Acc:HGNC:5576] | 24461 | 0.000 | 0.3410 | No |
| 64 | IGKV1D-39 | immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756] | 27740 | 0.000 | 0.2524 | No |
| 65 | IGKV1D-33 | immunoglobulin kappa variable 1D-33 [Source:HGNC Symbol;Acc:HGNC:5753] | 27742 | 0.000 | 0.2524 | No |
| 66 | IGKV1D-16 | immunoglobulin kappa variable 1D-16 [Source:HGNC Symbol;Acc:HGNC:5748] | 27774 | 0.000 | 0.2516 | No |
| 67 | IGKV1D-12 | immunoglobulin kappa variable 1D-12 [Source:HGNC Symbol;Acc:HGNC:5746] | 27781 | 0.000 | 0.2514 | No |
| 68 | CD3G | CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675] | 27919 | 0.000 | 0.2477 | No |
| 69 | IGLV6-57 | immunoglobulin lambda variable 6-57 [Source:HGNC Symbol;Acc:HGNC:5927] | 28033 | 0.000 | 0.2446 | No |
