Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.91736877 |
| Normalized Enrichment Score (NES) | 2.101835 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0528 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 10 | 4.992 | 0.1054 | Yes |
| 3 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 15 | 4.978 | 0.1580 | Yes |
| 4 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 16 | 4.972 | 0.2105 | Yes |
| 5 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 23 | 4.958 | 0.2628 | Yes |
| 6 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 26 | 4.953 | 0.3151 | Yes |
| 7 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 28 | 4.948 | 0.3674 | Yes |
| 8 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 73 | 4.750 | 0.4165 | Yes |
| 9 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 77 | 4.727 | 0.4664 | Yes |
| 10 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.5164 | Yes |
| 11 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 80 | 4.725 | 0.5664 | Yes |
| 12 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 84 | 4.682 | 0.6158 | Yes |
| 13 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 127 | 4.445 | 0.6617 | Yes |
| 14 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 209 | 4.082 | 0.7027 | Yes |
| 15 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 283 | 3.829 | 0.7412 | Yes |
| 16 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 320 | 3.725 | 0.7796 | Yes |
| 17 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 341 | 3.647 | 0.8177 | Yes |
| 18 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 422 | 3.383 | 0.8513 | Yes |
| 19 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 629 | 2.929 | 0.8767 | Yes |
| 20 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 951 | 2.397 | 0.8934 | Yes |
| 21 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 1423 | 1.881 | 0.9006 | Yes |
| 22 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 2180 | 1.310 | 0.8940 | Yes |
| 23 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2196 | 1.300 | 0.9074 | Yes |
| 24 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 2312 | 1.239 | 0.9174 | Yes |
| 25 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 3624 | 0.631 | 0.8887 | No |
| 26 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 5317 | 0.181 | 0.8449 | No |
| 27 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6018 | 0.000 | 0.8260 | No |
| 28 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6029 | 0.000 | 0.8257 | No |
| 29 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6032 | 0.000 | 0.8257 | No |
| 30 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13639 | 0.000 | 0.6204 | No |
| 31 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14634 | 0.000 | 0.5935 | No |
| 32 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14635 | 0.000 | 0.5935 | No |
| 33 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15800 | 0.000 | 0.5621 | No |
| 34 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15801 | 0.000 | 0.5621 | No |
| 35 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18253 | 0.000 | 0.4959 | No |
| 36 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19482 | 0.000 | 0.4628 | No |
| 37 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19491 | 0.000 | 0.4626 | No |
| 38 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19494 | 0.000 | 0.4625 | No |
| 39 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21453 | 0.000 | 0.4097 | No |
| 40 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 23139 | 0.000 | 0.3642 | No |
| 41 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 24111 | 0.000 | 0.3380 | No |
| 42 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 24112 | 0.000 | 0.3380 | No |
| 43 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 27899 | 0.000 | 0.2358 | No |
| 44 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 28016 | 0.000 | 0.2326 | No |
| 45 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 29072 | -0.244 | 0.2067 | No |
| 46 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 31462 | -0.914 | 0.1519 | No |
