Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8107239 |
| Normalized Enrichment Score (NES) | 1.9906133 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.771144E-4 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 16 | 4.972 | 0.0299 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 17 | 4.971 | 0.0602 | Yes |
| 3 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 32 | 4.931 | 0.0899 | Yes |
| 4 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 56 | 4.825 | 0.1186 | Yes |
| 5 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 64 | 4.795 | 0.1477 | Yes |
| 6 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 69 | 4.761 | 0.1766 | Yes |
| 7 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.2052 | Yes |
| 8 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 100 | 4.618 | 0.2328 | Yes |
| 9 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 129 | 4.432 | 0.2590 | Yes |
| 10 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 152 | 4.332 | 0.2848 | Yes |
| 11 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 154 | 4.328 | 0.3112 | Yes |
| 12 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 168 | 4.259 | 0.3368 | Yes |
| 13 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 254 | 3.943 | 0.3585 | Yes |
| 14 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 259 | 3.897 | 0.3822 | Yes |
| 15 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 261 | 3.891 | 0.4059 | Yes |
| 16 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 272 | 3.860 | 0.4291 | Yes |
| 17 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 283 | 3.829 | 0.4522 | Yes |
| 18 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 326 | 3.705 | 0.4737 | Yes |
| 19 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 335 | 3.674 | 0.4958 | Yes |
| 20 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 340 | 3.655 | 0.5180 | Yes |
| 21 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 375 | 3.557 | 0.5388 | Yes |
| 22 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 413 | 3.427 | 0.5587 | Yes |
| 23 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 427 | 3.359 | 0.5788 | Yes |
| 24 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 433 | 3.332 | 0.5990 | Yes |
| 25 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 470 | 3.287 | 0.6180 | Yes |
| 26 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 488 | 3.246 | 0.6374 | Yes |
| 27 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 530 | 3.156 | 0.6555 | Yes |
| 28 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 543 | 3.130 | 0.6742 | Yes |
| 29 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 600 | 2.986 | 0.6909 | Yes |
| 30 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 620 | 2.949 | 0.7084 | Yes |
| 31 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 730 | 2.794 | 0.7225 | Yes |
| 32 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 741 | 2.769 | 0.7391 | Yes |
| 33 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 774 | 2.696 | 0.7547 | Yes |
| 34 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 882 | 2.514 | 0.7671 | Yes |
| 35 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 920 | 2.458 | 0.7811 | Yes |
| 36 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 1329 | 1.995 | 0.7822 | Yes |
| 37 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1375 | 1.947 | 0.7929 | Yes |
| 38 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 1429 | 1.875 | 0.8029 | Yes |
| 39 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 2119 | 1.347 | 0.7925 | Yes |
| 40 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 2180 | 1.310 | 0.7988 | Yes |
| 41 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 2217 | 1.289 | 0.8057 | Yes |
| 42 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 2312 | 1.239 | 0.8107 | Yes |
| 43 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 4316 | 0.473 | 0.7595 | No |
| 44 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4726 | 0.369 | 0.7507 | No |
| 45 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 5313 | 0.182 | 0.7360 | No |
| 46 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 6258 | 0.000 | 0.7105 | No |
| 47 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 6829 | 0.000 | 0.6951 | No |
| 48 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8313 | 0.000 | 0.6550 | No |
| 49 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8450 | 0.000 | 0.6513 | No |
| 50 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10068 | 0.000 | 0.6076 | No |
| 51 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 10970 | 0.000 | 0.5833 | No |
| 52 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11288 | 0.000 | 0.5747 | No |
| 53 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13734 | 0.000 | 0.5087 | No |
| 54 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 17768 | 0.000 | 0.3997 | No |
| 55 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 18024 | 0.000 | 0.3928 | No |
| 56 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18253 | 0.000 | 0.3867 | No |
| 57 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18899 | 0.000 | 0.3692 | No |
| 58 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 19022 | 0.000 | 0.3659 | No |
| 59 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19477 | 0.000 | 0.3537 | No |
| 60 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19491 | 0.000 | 0.3533 | No |
| 61 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19493 | 0.000 | 0.3533 | No |
| 62 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 20447 | 0.000 | 0.3275 | No |
| 63 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 23919 | 0.000 | 0.2338 | No |
| 64 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 24731 | 0.000 | 0.2119 | No |
| 65 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 26962 | 0.000 | 0.1516 | No |
| 66 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 26997 | 0.000 | 0.1507 | No |
| 67 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27823 | 0.000 | 0.1284 | No |
| 68 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 29755 | -0.431 | 0.0789 | No |
| 69 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 29900 | -0.469 | 0.0778 | No |
| 70 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 31874 | -1.048 | 0.0309 | No |
| 71 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 32005 | -1.096 | 0.0341 | No |
| 72 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33049 | -1.475 | 0.0149 | No |
| 73 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 33800 | -1.809 | 0.0056 | No |
| 74 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34305 | -2.081 | 0.0047 | No |
| 75 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 34522 | -2.177 | 0.0121 | No |
| 76 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 34993 | -2.486 | 0.0146 | No |
| 77 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 36066 | -3.397 | 0.0063 | No |
| 78 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 36162 | -3.494 | 0.0251 | No |
