Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | WORSCHECH_TUMOR_REJECTION_UP |
| Enrichment Score (ES) | 0.85530925 |
| Normalized Enrichment Score (NES) | 2.0174658 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.3759017E-4 |
| FWER p-Value | 0.002 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0757 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 10 | 4.992 | 0.1513 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 28 | 4.948 | 0.2259 | Yes |
| 4 | IL4I1 | interleukin 4 induced 1 [Source:HGNC Symbol;Acc:HGNC:19094] | 39 | 4.914 | 0.3001 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 66 | 4.776 | 0.3719 | Yes |
| 6 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 69 | 4.761 | 0.4440 | Yes |
| 7 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 77 | 4.727 | 0.5155 | Yes |
| 8 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 130 | 4.430 | 0.5813 | Yes |
| 9 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 249 | 3.962 | 0.6382 | Yes |
| 10 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 558 | 3.089 | 0.6768 | Yes |
| 11 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 591 | 3.011 | 0.7216 | Yes |
| 12 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 1073 | 2.200 | 0.7419 | Yes |
| 13 | TLR6 | toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711] | 1114 | 2.149 | 0.7734 | Yes |
| 14 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 1411 | 1.896 | 0.7942 | Yes |
| 15 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 1490 | 1.822 | 0.8197 | Yes |
| 16 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1694 | 1.650 | 0.8393 | Yes |
| 17 | IRF4 | interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119] | 1919 | 1.455 | 0.8553 | Yes |
| 18 | NKRF | NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374] | 3938 | 0.511 | 0.8086 | No |
| 19 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 4405 | 0.470 | 0.8031 | No |
| 20 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 5077 | 0.251 | 0.7888 | No |
| 21 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 5211 | 0.211 | 0.7884 | No |
| 22 | TAGAP | T cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669] | 5625 | 0.102 | 0.7788 | No |
| 23 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 5998 | 0.000 | 0.7688 | No |
| 24 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6028 | 0.000 | 0.7680 | No |
| 25 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6029 | 0.000 | 0.7680 | No |
| 26 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 8072 | 0.000 | 0.7128 | No |
| 27 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8450 | 0.000 | 0.7027 | No |
| 28 | LY6H | lymphocyte antigen 6 family member H [Source:HGNC Symbol;Acc:HGNC:6728] | 8933 | 0.000 | 0.6896 | No |
| 29 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 9475 | 0.000 | 0.6750 | No |
| 30 | ACKR1 | atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035] | 10860 | 0.000 | 0.6376 | No |
| 31 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11259 | 0.000 | 0.6269 | No |
| 32 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 11975 | 0.000 | 0.6076 | No |
| 33 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12255 | 0.000 | 0.6001 | No |
| 34 | TCL1B | T cell leukemia/lymphoma 1B [Source:HGNC Symbol;Acc:HGNC:11649] | 12902 | 0.000 | 0.5826 | No |
| 35 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13282 | 0.000 | 0.5724 | No |
| 36 | IL31 | interleukin 31 [Source:HGNC Symbol;Acc:HGNC:19372] | 13682 | 0.000 | 0.5616 | No |
| 37 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14196 | 0.000 | 0.5477 | No |
| 38 | EBF4 | EBF family member 4 [Source:HGNC Symbol;Acc:HGNC:29278] | 14898 | 0.000 | 0.5288 | No |
| 39 | IL17RB | interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015] | 14968 | 0.000 | 0.5270 | No |
| 40 | IL36G | interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] | 15569 | 0.000 | 0.5107 | No |
| 41 | CLEC10A | C-type lectin domain containing 10A [Source:HGNC Symbol;Acc:HGNC:16916] | 15660 | 0.000 | 0.5083 | No |
| 42 | IL23R | interleukin 23 receptor [Source:HGNC Symbol;Acc:HGNC:19100] | 15796 | 0.000 | 0.5047 | No |
| 43 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17697 | 0.000 | 0.4534 | No |
| 44 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 17698 | 0.000 | 0.4534 | No |
| 45 | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 17769 | 0.000 | 0.4515 | No |
| 46 | IFNA13 | interferon alpha 13 [Source:HGNC Symbol;Acc:HGNC:5419] | 18175 | 0.000 | 0.4405 | No |
| 47 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18934 | 0.000 | 0.4201 | No |
| 48 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19493 | 0.000 | 0.4050 | No |
| 49 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19494 | 0.000 | 0.4050 | No |
| 50 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 20873 | 0.000 | 0.3678 | No |
| 51 | IL17F | interleukin 17F [Source:HGNC Symbol;Acc:HGNC:16404] | 24172 | 0.000 | 0.2787 | No |
| 52 | JCHAIN | joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713] | 24587 | 0.000 | 0.2675 | No |
| 53 | FASLG | Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936] | 24967 | 0.000 | 0.2573 | No |
| 54 | IFNG | interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438] | 25532 | 0.000 | 0.2421 | No |
| 55 | IRF6 | interferon regulatory factor 6 [Source:HGNC Symbol;Acc:HGNC:6121] | 26497 | 0.000 | 0.2160 | No |
| 56 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27821 | 0.000 | 0.1803 | No |
| 57 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 27831 | 0.000 | 0.1801 | No |
| 58 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 30018 | -0.505 | 0.1287 | No |
| 59 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 30670 | -0.675 | 0.1213 | No |
| 60 | NKIRAS2 | NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898] | 31778 | -1.017 | 0.1069 | No |
| 61 | TLR4 | toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] | 32202 | -1.176 | 0.1133 | No |
| 62 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 32464 | -1.232 | 0.1249 | No |
