Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | SRF_01 |
| Enrichment Score (ES) | 0.50392115 |
| Normalized Enrichment Score (NES) | 1.1597493 |
| Nominal p-value | 0.16483517 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 64 | 4.795 | 0.0840 | Yes |
| 2 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 377 | 3.549 | 0.1390 | Yes |
| 3 | ACTN1 | actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163] | 826 | 2.611 | 0.1736 | Yes |
| 4 | HOXB4 | homeobox B4 [Source:HGNC Symbol;Acc:HGNC:5115] | 839 | 2.587 | 0.2195 | Yes |
| 5 | ASB2 | ankyrin repeat and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:16012] | 851 | 2.555 | 0.2648 | Yes |
| 6 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 939 | 2.426 | 0.3058 | Yes |
| 7 | ITGB1BP2 | integrin subunit beta 1 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6154] | 1148 | 2.098 | 0.3377 | Yes |
| 8 | WDR1 | WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754] | 1354 | 1.971 | 0.3674 | Yes |
| 9 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 1686 | 1.657 | 0.3881 | Yes |
| 10 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 1784 | 1.557 | 0.4133 | Yes |
| 11 | CFL1 | cofilin 1 [Source:HGNC Symbol;Acc:HGNC:1874] | 2074 | 1.377 | 0.4301 | Yes |
| 12 | ACTR3 | actin related protein 3 [Source:HGNC Symbol;Acc:HGNC:170] | 2082 | 1.372 | 0.4544 | Yes |
| 13 | MYL6 | myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587] | 2107 | 1.355 | 0.4780 | Yes |
| 14 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] | 2199 | 1.296 | 0.4987 | Yes |
| 15 | MUS81 | MUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29814] | 2687 | 1.026 | 0.5039 | Yes |
| 16 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 3382 | 0.726 | 0.4982 | No |
| 17 | TGFB1I1 | transforming growth factor beta 1 induced transcript 1 [Source:HGNC Symbol;Acc:HGNC:11767] | 4061 | 0.474 | 0.4883 | No |
| 18 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 4432 | 0.463 | 0.4866 | No |
| 19 | MYH11 | myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569] | 4897 | 0.317 | 0.4797 | No |
| 20 | SCOC | short coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:20335] | 5064 | 0.255 | 0.4798 | No |
| 21 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5182 | 0.219 | 0.4806 | No |
| 22 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 7799 | 0.000 | 0.4099 | No |
| 23 | NPAS4 | neuronal PAS domain protein 4 [Source:HGNC Symbol;Acc:HGNC:18983] | 9490 | 0.000 | 0.3643 | No |
| 24 | SUSD1 | sushi domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25413] | 9960 | 0.000 | 0.3516 | No |
| 25 | PRM1 | protamine 1 [Source:HGNC Symbol;Acc:HGNC:9447] | 11357 | 0.000 | 0.3140 | No |
| 26 | TNMD | tenomodulin [Source:HGNC Symbol;Acc:HGNC:17757] | 14828 | 0.000 | 0.2203 | No |
| 27 | CA3 | carbonic anhydrase 3 [Source:HGNC Symbol;Acc:HGNC:1374] | 15614 | 0.000 | 0.1991 | No |
| 28 | PHOX2B | paired like homeobox 2B [Source:HGNC Symbol;Acc:HGNC:9143] | 16235 | 0.000 | 0.1823 | No |
| 29 | GPR20 | G protein-coupled receptor 20 [Source:HGNC Symbol;Acc:HGNC:4475] | 17458 | 0.000 | 0.1494 | No |
| 30 | STX10 | syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428] | 17645 | 0.000 | 0.1443 | No |
| 31 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6285] | 21843 | 0.000 | 0.0310 | No |
| 32 | IL17B | interleukin 17B [Source:HGNC Symbol;Acc:HGNC:5982] | 24175 | 0.000 | -0.0319 | No |
| 33 | IGF2-AS | IGF2 antisense RNA [Source:HGNC Symbol;Acc:HGNC:14062] | 25604 | 0.000 | -0.0705 | No |
| 34 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 27120 | 0.000 | -0.1114 | No |
| 35 | CNN2 | calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156] | 28257 | -0.041 | -0.1413 | No |
| 36 | TPM1 | tropomyosin 1 [Source:HGNC Symbol;Acc:HGNC:12010] | 28834 | -0.193 | -0.1534 | No |
| 37 | CALD1 | caldesmon 1 [Source:HGNC Symbol;Acc:HGNC:1441] | 28946 | -0.218 | -0.1525 | No |
| 38 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 [Source:HGNC Symbol;Acc:HGNC:7237] | 29334 | -0.322 | -0.1572 | No |
| 39 | PRUNE2 | prune homolog 2 with BCH domain [Source:HGNC Symbol;Acc:HGNC:25209] | 29598 | -0.387 | -0.1574 | No |
| 40 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 29900 | -0.469 | -0.1571 | No |
| 41 | PLCB3 | phospholipase C beta 3 [Source:HGNC Symbol;Acc:HGNC:9056] | 30982 | -0.761 | -0.1727 | No |
| 42 | SETD2 | SET domain containing 2, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:18420] | 31448 | -0.910 | -0.1690 | No |
| 43 | TAZ | tafazzin [Source:HGNC Symbol;Acc:HGNC:11577] | 31548 | -0.935 | -0.1550 | No |
| 44 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 32005 | -1.096 | -0.1477 | No |
| 45 | TNNC1 | troponin C1, slow skeletal and cardiac type [Source:HGNC Symbol;Acc:HGNC:11943] | 32816 | -1.362 | -0.1452 | No |
| 46 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33049 | -1.475 | -0.1251 | No |
| 47 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 33424 | -1.630 | -0.1061 | No |
| 48 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 34746 | -2.313 | -0.1004 | No |
| 49 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35454 | -2.801 | -0.0694 | No |
| 50 | DIXDC1 | DIX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23695] | 35800 | -3.141 | -0.0226 | No |
| 51 | VCL | vinculin [Source:HGNC Symbol;Acc:HGNC:12665] | 35873 | -3.213 | 0.0329 | No |
