Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_BUB1B |
| Enrichment Score (ES) | -0.86642593 |
| Normalized Enrichment Score (NES) | -1.6813467 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.953662E-5 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 3780 | 0.570 | -0.0982 | No |
| 2 | MRPL39 | mitochondrial ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:14027] | 4041 | 0.474 | -0.1021 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6207 | No |
| 4 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 29018 | -0.242 | -0.7747 | No |
| 5 | CSE1L | chromosome segregation 1 like [Source:HGNC Symbol;Acc:HGNC:2431] | 31941 | -1.072 | -0.8464 | No |
| 6 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8427 | No |
| 7 | NUP205 | nucleoporin 205 [Source:HGNC Symbol;Acc:HGNC:18658] | 32221 | -1.186 | -0.8384 | No |
| 8 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8307 | No |
| 9 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 32737 | -1.335 | -0.8353 | No |
| 10 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33291 | -1.571 | -0.8397 | No |
| 11 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34283 | -2.068 | -0.8526 | Yes |
| 12 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.8435 | Yes |
| 13 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35015 | -2.498 | -0.8412 | Yes |
| 14 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.8274 | Yes |
| 15 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.8102 | Yes |
| 16 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35351 | -2.722 | -0.7970 | Yes |
| 17 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.7797 | Yes |
| 18 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.7652 | Yes |
| 19 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.7487 | Yes |
| 20 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.7300 | Yes |
| 21 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.7132 | Yes |
| 22 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.6913 | Yes |
| 23 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36110 | -3.445 | -0.6685 | Yes |
| 24 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36128 | -3.460 | -0.6458 | Yes |
| 25 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.6231 | Yes |
| 26 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36160 | -3.493 | -0.5998 | Yes |
| 27 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36163 | -3.495 | -0.5764 | Yes |
| 28 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36172 | -3.498 | -0.5532 | Yes |
| 29 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36324 | -3.663 | -0.5327 | Yes |
| 30 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36366 | -3.704 | -0.5090 | Yes |
| 31 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36460 | -3.819 | -0.4859 | Yes |
| 32 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.4608 | Yes |
| 33 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.4353 | Yes |
| 34 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36518 | -3.905 | -0.4092 | Yes |
| 35 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.3841 | Yes |
| 36 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.3577 | Yes |
| 37 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.3315 | Yes |
| 38 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36660 | -4.066 | -0.3053 | Yes |
| 39 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.2781 | Yes |
| 40 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 36703 | -4.132 | -0.2514 | Yes |
| 41 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.2238 | Yes |
| 42 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.1968 | Yes |
| 43 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.1692 | Yes |
| 44 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36795 | -4.256 | -0.1409 | Yes |
| 45 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.1129 | Yes |
| 46 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0839 | Yes |
| 47 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0549 | Yes |
| 48 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36917 | -4.488 | -0.0258 | Yes |
| 49 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | 0.0040 | Yes |
