Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_CCNA2 |
| Enrichment Score (ES) | -0.88286394 |
| Normalized Enrichment Score (NES) | -1.752511 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0869 | No |
| 2 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 15814 | 0.000 | -0.4237 | No |
| 3 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 21014 | 0.000 | -0.5641 | No |
| 4 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6246 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8580 | No |
| 6 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8564 | No |
| 7 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 32737 | -1.335 | -0.8639 | No |
| 8 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.8719 | No |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8646 | No |
| 10 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8698 | No |
| 11 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.8734 | Yes |
| 12 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.8688 | Yes |
| 13 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 34580 | -2.221 | -0.8612 | Yes |
| 14 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.8628 | Yes |
| 15 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.8516 | Yes |
| 16 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.8413 | Yes |
| 17 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.8296 | Yes |
| 18 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.8179 | Yes |
| 19 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35361 | -2.726 | -0.8105 | Yes |
| 20 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.7987 | Yes |
| 21 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35409 | -2.763 | -0.7865 | Yes |
| 22 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.7769 | Yes |
| 23 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.7676 | Yes |
| 24 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.7540 | Yes |
| 25 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.7408 | Yes |
| 26 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.7266 | Yes |
| 27 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.7133 | Yes |
| 28 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 35853 | -3.190 | -0.6991 | Yes |
| 29 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35958 | -3.323 | -0.6867 | Yes |
| 30 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.6734 | Yes |
| 31 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.6582 | Yes |
| 32 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36086 | -3.421 | -0.6434 | Yes |
| 33 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.6279 | Yes |
| 34 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36110 | -3.445 | -0.6125 | Yes |
| 35 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.5976 | Yes |
| 36 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36163 | -3.495 | -0.5818 | Yes |
| 37 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36324 | -3.663 | -0.5694 | Yes |
| 38 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.5534 | Yes |
| 39 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36460 | -3.819 | -0.5386 | Yes |
| 40 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36469 | -3.830 | -0.5212 | Yes |
| 41 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.5040 | Yes |
| 42 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.4868 | Yes |
| 43 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36518 | -3.905 | -0.4690 | Yes |
| 44 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36526 | -3.918 | -0.4513 | Yes |
| 45 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.4343 | Yes |
| 46 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.4161 | Yes |
| 47 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.3981 | Yes |
| 48 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.3798 | Yes |
| 49 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36591 | -3.999 | -0.3615 | Yes |
| 50 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36605 | -4.013 | -0.3434 | Yes |
| 51 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.3250 | Yes |
| 52 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.3069 | Yes |
| 53 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36660 | -4.066 | -0.2893 | Yes |
| 54 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.2708 | Yes |
| 55 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.2529 | Yes |
| 56 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.2348 | Yes |
| 57 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.2163 | Yes |
| 58 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36795 | -4.256 | -0.1970 | Yes |
| 59 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36803 | -4.278 | -0.1776 | Yes |
| 60 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1585 | Yes |
| 61 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.1386 | Yes |
| 62 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.1189 | Yes |
| 63 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0993 | Yes |
| 64 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36887 | -4.439 | -0.0792 | Yes |
| 65 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36915 | -4.481 | -0.0594 | Yes |
| 66 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36917 | -4.488 | -0.0388 | Yes |
| 67 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | -0.0186 | Yes |
| 68 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 37062 | -4.928 | 0.0008 | Yes |
