Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_CKS2 |
| Enrichment Score (ES) | -0.83806443 |
| Normalized Enrichment Score (NES) | -1.6304225 |
| Nominal p-value | 0.0 |
| FDR q-value | 9.003595E-4 |
| FWER p-Value | 0.019 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2900 | 0.926 | -0.0713 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0777 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3364 | 0.733 | -0.0727 | No |
| 4 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5379 | 0.166 | -0.1258 | No |
| 5 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 5393 | 0.161 | -0.1250 | No |
| 6 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.1319 | No |
| 7 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6064 | No |
| 8 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 29735 | -0.425 | -0.7782 | No |
| 9 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 29933 | -0.478 | -0.7799 | No |
| 10 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8296 | Yes |
| 11 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8245 | Yes |
| 12 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32551 | -1.246 | -0.8237 | Yes |
| 13 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32691 | -1.316 | -0.8175 | Yes |
| 14 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.8221 | Yes |
| 15 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8103 | Yes |
| 16 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8102 | Yes |
| 17 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.8076 | Yes |
| 18 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.7967 | Yes |
| 19 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34858 | -2.395 | -0.7889 | Yes |
| 20 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.7759 | Yes |
| 21 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.7582 | Yes |
| 22 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.7389 | Yes |
| 23 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.7242 | Yes |
| 24 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.7066 | Yes |
| 25 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.6856 | Yes |
| 26 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.6663 | Yes |
| 27 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.6436 | Yes |
| 28 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.6214 | Yes |
| 29 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 35926 | -3.289 | -0.6003 | Yes |
| 30 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35958 | -3.323 | -0.5762 | Yes |
| 31 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.5534 | Yes |
| 32 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36080 | -3.411 | -0.5284 | Yes |
| 33 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36110 | -3.445 | -0.5033 | Yes |
| 34 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36469 | -3.830 | -0.4842 | Yes |
| 35 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.4557 | Yes |
| 36 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.4270 | Yes |
| 37 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.3988 | Yes |
| 38 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.3690 | Yes |
| 39 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.3393 | Yes |
| 40 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36605 | -4.013 | -0.3095 | Yes |
| 41 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.2794 | Yes |
| 42 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.2494 | Yes |
| 43 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.2207 | Yes |
| 44 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.1903 | Yes |
| 45 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1599 | Yes |
| 46 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.1273 | Yes |
| 47 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0947 | Yes |
| 48 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0621 | Yes |
| 49 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36915 | -4.481 | -0.0295 | Yes |
| 50 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | 0.0040 | Yes |
