Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_FEN1 |
| Enrichment Score (ES) | -0.8386141 |
| Normalized Enrichment Score (NES) | -1.6335247 |
| Nominal p-value | 0.0012315271 |
| FDR q-value | 9.010059E-4 |
| FWER p-Value | 0.018 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 1514 | 1.792 | -0.0289 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0733 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3364 | 0.733 | -0.0689 | No |
| 4 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5379 | 0.166 | -0.1221 | No |
| 5 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 5753 | 0.064 | -0.1318 | No |
| 6 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15439 | 0.000 | -0.3933 | No |
| 7 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6042 | No |
| 8 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 29933 | -0.478 | -0.7814 | No |
| 9 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 31439 | -0.907 | -0.8159 | No |
| 10 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 31980 | -1.085 | -0.8233 | No |
| 11 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8186 | No |
| 12 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8145 | No |
| 13 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32551 | -1.246 | -0.8147 | No |
| 14 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8244 | No |
| 15 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8257 | Yes |
| 16 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34283 | -2.068 | -0.8248 | Yes |
| 17 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.8110 | Yes |
| 18 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 34343 | -2.114 | -0.7983 | Yes |
| 19 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.7876 | Yes |
| 20 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 34656 | -2.264 | -0.7772 | Yes |
| 21 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34858 | -2.395 | -0.7665 | Yes |
| 22 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.7570 | Yes |
| 23 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35154 | -2.602 | -0.7396 | Yes |
| 24 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.7223 | Yes |
| 25 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.7050 | Yes |
| 26 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -2.698 | -0.6910 | Yes |
| 27 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.6744 | Yes |
| 28 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35403 | -2.757 | -0.6562 | Yes |
| 29 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35534 | -2.879 | -0.6404 | Yes |
| 30 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35545 | -2.882 | -0.6214 | Yes |
| 31 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.6021 | Yes |
| 32 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.5834 | Yes |
| 33 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.5666 | Yes |
| 34 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.5464 | Yes |
| 35 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.5267 | Yes |
| 36 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35958 | -3.323 | -0.5090 | Yes |
| 37 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.4886 | Yes |
| 38 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.4663 | Yes |
| 39 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36080 | -3.411 | -0.4441 | Yes |
| 40 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.4269 | Yes |
| 41 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.4049 | Yes |
| 42 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36526 | -3.918 | -0.3790 | Yes |
| 43 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.3536 | Yes |
| 44 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.3270 | Yes |
| 45 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.3006 | Yes |
| 46 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.2741 | Yes |
| 47 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.2474 | Yes |
| 48 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.2213 | Yes |
| 49 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.1947 | Yes |
| 50 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.1677 | Yes |
| 51 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36821 | -4.303 | -0.1407 | Yes |
| 52 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1119 | Yes |
| 53 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.0828 | Yes |
| 54 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0538 | Yes |
| 55 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36887 | -4.439 | -0.0250 | Yes |
| 56 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | 0.0040 | Yes |
