Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_MCM4 |
| Enrichment Score (ES) | -0.8748688 |
| Normalized Enrichment Score (NES) | -1.6843913 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.1192078E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0857 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 3780 | 0.570 | -0.0940 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6197 | No |
| 4 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 29018 | -0.242 | -0.7738 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8498 | No |
| 6 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8464 | No |
| 7 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33291 | -1.571 | -0.8652 | Yes |
| 8 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.8558 | Yes |
| 9 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8582 | Yes |
| 10 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34283 | -2.068 | -0.8585 | Yes |
| 11 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.8506 | Yes |
| 12 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35015 | -2.498 | -0.8497 | Yes |
| 13 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.8374 | Yes |
| 14 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.8217 | Yes |
| 15 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.8059 | Yes |
| 16 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35351 | -2.722 | -0.7940 | Yes |
| 17 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.7783 | Yes |
| 18 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35403 | -2.757 | -0.7616 | Yes |
| 19 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.7485 | Yes |
| 20 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35623 | -2.974 | -0.7313 | Yes |
| 21 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.7152 | Yes |
| 22 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.6967 | Yes |
| 23 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.6787 | Yes |
| 24 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.6597 | Yes |
| 25 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.6415 | Yes |
| 26 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.6262 | Yes |
| 27 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.6058 | Yes |
| 28 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.5859 | Yes |
| 29 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36128 | -3.460 | -0.5655 | Yes |
| 30 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.5448 | Yes |
| 31 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36160 | -3.493 | -0.5235 | Yes |
| 32 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36163 | -3.495 | -0.5021 | Yes |
| 33 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36172 | -3.498 | -0.4809 | Yes |
| 34 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36324 | -3.663 | -0.4625 | Yes |
| 35 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.4408 | Yes |
| 36 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.4206 | Yes |
| 37 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.3973 | Yes |
| 38 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36518 | -3.905 | -0.3735 | Yes |
| 39 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36526 | -3.918 | -0.3497 | Yes |
| 40 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.3265 | Yes |
| 41 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.3024 | Yes |
| 42 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.2785 | Yes |
| 43 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.2548 | Yes |
| 44 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.2305 | Yes |
| 45 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.2059 | Yes |
| 46 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.1808 | Yes |
| 47 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36795 | -4.256 | -0.1549 | Yes |
| 48 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1293 | Yes |
| 49 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.1027 | Yes |
| 50 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0762 | Yes |
| 51 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0497 | Yes |
| 52 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36917 | -4.488 | -0.0233 | Yes |
| 53 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | 0.0040 | Yes |
