Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RFC4 |
| Enrichment Score (ES) | -0.83077884 |
| Normalized Enrichment Score (NES) | -1.6473136 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.732249E-4 |
| FWER p-Value | 0.012 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RANBP1 | RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847] | 3098 | 0.839 | -0.0779 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0795 | No |
| 3 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 5393 | 0.161 | -0.1337 | No |
| 4 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.1407 | No |
| 5 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 5753 | 0.064 | -0.1423 | No |
| 6 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 5807 | 0.045 | -0.1434 | No |
| 7 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6145 | No |
| 8 | SNRPE | small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:HGNC:11161] | 29172 | -0.274 | -0.7724 | No |
| 9 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 29735 | -0.425 | -0.7847 | No |
| 10 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 29933 | -0.478 | -0.7868 | No |
| 11 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 30386 | -0.581 | -0.7950 | No |
| 12 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 31712 | -0.997 | -0.8240 | Yes |
| 13 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 31867 | -1.046 | -0.8210 | Yes |
| 14 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 31954 | -1.077 | -0.8159 | Yes |
| 15 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8118 | Yes |
| 16 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8076 | Yes |
| 17 | ITGB3BP | integrin subunit beta 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6157] | 32316 | -1.229 | -0.8014 | Yes |
| 18 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.8172 | Yes |
| 19 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8064 | Yes |
| 20 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 33511 | -1.669 | -0.8006 | Yes |
| 21 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.7961 | Yes |
| 22 | H2AZ1 | H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741] | 34044 | -1.937 | -0.7893 | Yes |
| 23 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.7864 | Yes |
| 24 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 34580 | -2.221 | -0.7739 | Yes |
| 25 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 34656 | -2.264 | -0.7605 | Yes |
| 26 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 34813 | -2.360 | -0.7486 | Yes |
| 27 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34858 | -2.395 | -0.7334 | Yes |
| 28 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.7217 | Yes |
| 29 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.7047 | Yes |
| 30 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.6886 | Yes |
| 31 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.6711 | Yes |
| 32 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.6535 | Yes |
| 33 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.6406 | Yes |
| 34 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 35422 | -2.773 | -0.6224 | Yes |
| 35 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.6068 | Yes |
| 36 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.5896 | Yes |
| 37 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.5690 | Yes |
| 38 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.5488 | Yes |
| 39 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.5275 | Yes |
| 40 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.5071 | Yes |
| 41 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36017 | -3.355 | -0.4890 | Yes |
| 42 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.4665 | Yes |
| 43 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.4438 | Yes |
| 44 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36119 | -3.455 | -0.4219 | Yes |
| 45 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36160 | -3.493 | -0.3991 | Yes |
| 46 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.3793 | Yes |
| 47 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36371 | -3.711 | -0.3542 | Yes |
| 48 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36460 | -3.819 | -0.3305 | Yes |
| 49 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36605 | -4.013 | -0.3070 | Yes |
| 50 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.2795 | Yes |
| 51 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.2523 | Yes |
| 52 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.2258 | Yes |
| 53 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.1986 | Yes |
| 54 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.1710 | Yes |
| 55 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36821 | -4.303 | -0.1434 | Yes |
| 56 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1141 | Yes |
| 57 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.0845 | Yes |
| 58 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0549 | Yes |
| 59 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0253 | Yes |
| 60 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | 0.0040 | Yes |
