Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM1 |
| Enrichment Score (ES) | -0.8235012 |
| Normalized Enrichment Score (NES) | -1.6686825 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.2524993E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PSMD14 | proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889] | 2576 | 1.092 | -0.0647 | No |
| 2 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 2582 | 1.086 | -0.0600 | No |
| 3 | CCT6A | chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620] | 2694 | 1.022 | -0.0585 | No |
| 4 | PTGES3 | prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049] | 2831 | 0.962 | -0.0579 | No |
| 5 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2900 | 0.926 | -0.0556 | No |
| 6 | USP14 | ubiquitin specific peptidase 14 [Source:HGNC Symbol;Acc:HGNC:12612] | 3263 | 0.773 | -0.0619 | No |
| 7 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0608 | No |
| 8 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3364 | 0.733 | -0.0580 | No |
| 9 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 3780 | 0.570 | -0.0667 | No |
| 10 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5379 | 0.166 | -0.1091 | No |
| 11 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 5646 | 0.094 | -0.1159 | No |
| 12 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.1163 | No |
| 13 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 5807 | 0.045 | -0.1196 | No |
| 14 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15439 | 0.000 | -0.3798 | No |
| 15 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 15814 | 0.000 | -0.3900 | No |
| 16 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.5910 | No |
| 17 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 29018 | -0.242 | -0.7457 | No |
| 18 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 29933 | -0.478 | -0.7682 | No |
| 19 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 30247 | -0.538 | -0.7743 | No |
| 20 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30436 | -0.597 | -0.7767 | No |
| 21 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 31954 | -1.077 | -0.8129 | No |
| 22 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 31980 | -1.085 | -0.8087 | No |
| 23 | NUP37 | nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929] | 32001 | -1.093 | -0.8044 | No |
| 24 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8017 | No |
| 25 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8003 | No |
| 26 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32551 | -1.246 | -0.8032 | No |
| 27 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.8165 | Yes |
| 28 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8094 | Yes |
| 29 | FH | fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700] | 33386 | -1.614 | -0.8044 | Yes |
| 30 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.8076 | Yes |
| 31 | CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906] | 34158 | -1.999 | -0.8082 | Yes |
| 32 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34283 | -2.068 | -0.8024 | Yes |
| 33 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.7932 | Yes |
| 34 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 34343 | -2.114 | -0.7853 | Yes |
| 35 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.7794 | Yes |
| 36 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34858 | -2.395 | -0.7789 | Yes |
| 37 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.7732 | Yes |
| 38 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.7623 | Yes |
| 39 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.7524 | Yes |
| 40 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.7410 | Yes |
| 41 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.7296 | Yes |
| 42 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -2.698 | -0.7216 | Yes |
| 43 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35351 | -2.722 | -0.7102 | Yes |
| 44 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.6991 | Yes |
| 45 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35403 | -2.757 | -0.6870 | Yes |
| 46 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.6780 | Yes |
| 47 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.6659 | Yes |
| 48 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.6559 | Yes |
| 49 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.6427 | Yes |
| 50 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.6299 | Yes |
| 51 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.6160 | Yes |
| 52 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.6031 | Yes |
| 53 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35958 | -3.323 | -0.5916 | Yes |
| 54 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.5787 | Yes |
| 55 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.5639 | Yes |
| 56 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36080 | -3.411 | -0.5494 | Yes |
| 57 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36086 | -3.421 | -0.5343 | Yes |
| 58 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.5192 | Yes |
| 59 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.5052 | Yes |
| 60 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36160 | -3.493 | -0.4897 | Yes |
| 61 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36163 | -3.495 | -0.4742 | Yes |
| 62 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.4630 | Yes |
| 63 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36469 | -3.830 | -0.4488 | Yes |
| 64 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.4321 | Yes |
| 65 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.4153 | Yes |
| 66 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36518 | -3.905 | -0.3980 | Yes |
| 67 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36526 | -3.918 | -0.3808 | Yes |
| 68 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.3643 | Yes |
| 69 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.3466 | Yes |
| 70 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.3291 | Yes |
| 71 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.3112 | Yes |
| 72 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36591 | -3.999 | -0.2934 | Yes |
| 73 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36605 | -4.013 | -0.2758 | Yes |
| 74 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.2579 | Yes |
| 75 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.2403 | Yes |
| 76 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.2234 | Yes |
| 77 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.2060 | Yes |
| 78 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.1884 | Yes |
| 79 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.1703 | Yes |
| 80 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36795 | -4.256 | -0.1516 | Yes |
| 81 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36821 | -4.303 | -0.1330 | Yes |
| 82 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1140 | Yes |
| 83 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.0947 | Yes |
| 84 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0755 | Yes |
| 85 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0564 | Yes |
| 86 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36887 | -4.439 | -0.0369 | Yes |
| 87 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | -0.0180 | Yes |
| 88 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 37062 | -4.928 | 0.0008 | Yes |
