Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM2 |
| Enrichment Score (ES) | -0.88111323 |
| Normalized Enrichment Score (NES) | -1.643693 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.8725407E-4 |
| FWER p-Value | 0.013 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.6276 | No |
| 2 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8576 | No |
| 3 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.8526 | No |
| 4 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33291 | -1.571 | -0.8694 | Yes |
| 5 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.8579 | Yes |
| 6 | SMC1A | structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111] | 33619 | -1.732 | -0.8535 | Yes |
| 7 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.8608 | Yes |
| 8 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.8595 | Yes |
| 9 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.8403 | Yes |
| 10 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 35351 | -2.722 | -0.8252 | Yes |
| 11 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.8089 | Yes |
| 12 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.7912 | Yes |
| 13 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.7691 | Yes |
| 14 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.7469 | Yes |
| 15 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.7275 | Yes |
| 16 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.7030 | Yes |
| 17 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.6785 | Yes |
| 18 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36163 | -3.495 | -0.6527 | Yes |
| 19 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36172 | -3.498 | -0.6269 | Yes |
| 20 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36469 | -3.830 | -0.6063 | Yes |
| 21 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.5781 | Yes |
| 22 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.5496 | Yes |
| 23 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36526 | -3.918 | -0.5208 | Yes |
| 24 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.4925 | Yes |
| 25 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.4631 | Yes |
| 26 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36591 | -3.999 | -0.4333 | Yes |
| 27 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36605 | -4.013 | -0.4037 | Yes |
| 28 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.3738 | Yes |
| 29 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36660 | -4.066 | -0.3450 | Yes |
| 30 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.3148 | Yes |
| 31 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.2850 | Yes |
| 32 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.2549 | Yes |
| 33 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.2241 | Yes |
| 34 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36795 | -4.256 | -0.1927 | Yes |
| 35 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1613 | Yes |
| 36 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.1290 | Yes |
| 37 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0968 | Yes |
| 38 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0644 | Yes |
| 39 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36917 | -4.488 | -0.0321 | Yes |
| 40 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 37062 | -4.928 | 0.0008 | Yes |
