Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_SMC4L1 |
| Enrichment Score (ES) | -0.8130526 |
| Normalized Enrichment Score (NES) | -1.6724905 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.457272E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 1514 | 1.792 | -0.0322 | No |
| 2 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 2582 | 1.086 | -0.0557 | No |
| 3 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 2900 | 0.926 | -0.0597 | No |
| 4 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3345 | 0.744 | -0.0681 | No |
| 5 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3364 | 0.733 | -0.0650 | No |
| 6 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 4515 | 0.437 | -0.0940 | No |
| 7 | NUP153 | nucleoporin 153 [Source:HGNC Symbol;Acc:HGNC:8062] | 5067 | 0.254 | -0.1076 | No |
| 8 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5379 | 0.166 | -0.1152 | No |
| 9 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 5646 | 0.094 | -0.1219 | No |
| 10 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.1223 | No |
| 11 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 5753 | 0.064 | -0.1240 | No |
| 12 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15439 | 0.000 | -0.3857 | No |
| 13 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23253 | 0.000 | -0.5969 | No |
| 14 | HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13729] | 29330 | -0.321 | -0.7595 | No |
| 15 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 29933 | -0.478 | -0.7734 | No |
| 16 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 30247 | -0.538 | -0.7792 | No |
| 17 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30436 | -0.597 | -0.7814 | No |
| 18 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 31439 | -0.907 | -0.8041 | No |
| 19 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 31712 | -0.997 | -0.8065 | No |
| 20 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 31954 | -1.077 | -0.8078 | Yes |
| 21 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 31980 | -1.085 | -0.8032 | Yes |
| 22 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32088 | -1.131 | -0.8005 | Yes |
| 23 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.7986 | Yes |
| 24 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32551 | -1.246 | -0.8011 | Yes |
| 25 | ANP32B | acidic nuclear phosphoprotein 32 family member B [Source:HGNC Symbol;Acc:HGNC:16677] | 32727 | -1.331 | -0.7993 | Yes |
| 26 | EXOSC8 | exosome component 8 [Source:HGNC Symbol;Acc:HGNC:17035] | 33215 | -1.540 | -0.8050 | Yes |
| 27 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.7996 | Yes |
| 28 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.7919 | Yes |
| 29 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 33618 | -1.730 | -0.7919 | Yes |
| 30 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.7881 | Yes |
| 31 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 34002 | -1.913 | -0.7841 | Yes |
| 32 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34283 | -2.068 | -0.7816 | Yes |
| 33 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34287 | -2.069 | -0.7715 | Yes |
| 34 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 34343 | -2.114 | -0.7627 | Yes |
| 35 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34480 | -2.139 | -0.7559 | Yes |
| 36 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34858 | -2.395 | -0.7544 | Yes |
| 37 | DEK | DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768] | 34944 | -2.441 | -0.7448 | Yes |
| 38 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.7358 | Yes |
| 39 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35087 | -2.553 | -0.7238 | Yes |
| 40 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35150 | -2.598 | -0.7128 | Yes |
| 41 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35154 | -2.602 | -0.7002 | Yes |
| 42 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.6876 | Yes |
| 43 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.6751 | Yes |
| 44 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 35322 | -2.698 | -0.6660 | Yes |
| 45 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35393 | -2.750 | -0.6544 | Yes |
| 46 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35403 | -2.757 | -0.6412 | Yes |
| 47 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35534 | -2.879 | -0.6307 | Yes |
| 48 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35545 | -2.882 | -0.6169 | Yes |
| 49 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35546 | -2.882 | -0.6028 | Yes |
| 50 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35585 | -2.932 | -0.5895 | Yes |
| 51 | FBXO5 | F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584] | 35655 | -3.023 | -0.5766 | Yes |
| 52 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 35722 | -3.059 | -0.5635 | Yes |
| 53 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.5489 | Yes |
| 54 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35788 | -3.128 | -0.5349 | Yes |
| 55 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 35926 | -3.289 | -0.5226 | Yes |
| 56 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35958 | -3.323 | -0.5072 | Yes |
| 57 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.4929 | Yes |
| 58 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.4768 | Yes |
| 59 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36080 | -3.411 | -0.4608 | Yes |
| 60 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36086 | -3.421 | -0.4443 | Yes |
| 61 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36096 | -3.434 | -0.4277 | Yes |
| 62 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.4122 | Yes |
| 63 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36161 | -3.494 | -0.3954 | Yes |
| 64 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 36163 | -3.495 | -0.3783 | Yes |
| 65 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36360 | -3.688 | -0.3656 | Yes |
| 66 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 36488 | -3.857 | -0.3502 | Yes |
| 67 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36512 | -3.898 | -0.3318 | Yes |
| 68 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36526 | -3.918 | -0.3131 | Yes |
| 69 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.2949 | Yes |
| 70 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36576 | -3.975 | -0.2756 | Yes |
| 71 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.2564 | Yes |
| 72 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36591 | -3.999 | -0.2369 | Yes |
| 73 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36606 | -4.015 | -0.2177 | Yes |
| 74 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 36619 | -4.031 | -0.1983 | Yes |
| 75 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36668 | -4.079 | -0.1797 | Yes |
| 76 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.1606 | Yes |
| 77 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.1413 | Yes |
| 78 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36821 | -4.303 | -0.1221 | Yes |
| 79 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36833 | -4.338 | -0.1012 | Yes |
| 80 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36838 | -4.351 | -0.0801 | Yes |
| 81 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36851 | -4.372 | -0.0591 | Yes |
| 82 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36876 | -4.426 | -0.0381 | Yes |
| 83 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36887 | -4.439 | -0.0167 | Yes |
| 84 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | 0.0040 | Yes |
