Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_121 |
| Enrichment Score (ES) | 0.6121694 |
| Normalized Enrichment Score (NES) | 1.5568079 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.21224798 |
| FWER p-Value | 0.844 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0312 | Yes |
| 2 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 16 | 4.972 | 0.0620 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 23 | 4.958 | 0.0928 | Yes |
| 4 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 28 | 4.948 | 0.1237 | Yes |
| 5 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 46 | 4.877 | 0.1538 | Yes |
| 6 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 64 | 4.795 | 0.1833 | Yes |
| 7 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 73 | 4.750 | 0.2128 | Yes |
| 8 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.2423 | Yes |
| 9 | VEGFC | vascular endothelial growth factor C [Source:HGNC Symbol;Acc:HGNC:12682] | 82 | 4.706 | 0.2717 | Yes |
| 10 | MXD1 | MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] | 103 | 4.612 | 0.3000 | Yes |
| 11 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 171 | 4.251 | 0.3248 | Yes |
| 12 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 220 | 4.061 | 0.3489 | Yes |
| 13 | ZEB1 | zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642] | 258 | 3.910 | 0.3724 | Yes |
| 14 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 283 | 3.829 | 0.3957 | Yes |
| 15 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 313 | 3.741 | 0.4183 | Yes |
| 16 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 341 | 3.647 | 0.4404 | Yes |
| 17 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 346 | 3.620 | 0.4629 | Yes |
| 18 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 422 | 3.383 | 0.4821 | Yes |
| 19 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 425 | 3.363 | 0.5031 | Yes |
| 20 | TSPAN3 | tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752] | 555 | 3.097 | 0.5190 | Yes |
| 21 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 557 | 3.091 | 0.5383 | Yes |
| 22 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 752 | 2.737 | 0.5502 | Yes |
| 23 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 828 | 2.609 | 0.5645 | Yes |
| 24 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 1035 | 2.264 | 0.5731 | Yes |
| 25 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 1073 | 2.200 | 0.5858 | Yes |
| 26 | PSPHP1 | phosphoserine phosphatase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9578] | 1228 | 2.075 | 0.5946 | Yes |
| 27 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 1329 | 1.995 | 0.6044 | Yes |
| 28 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1470 | 1.842 | 0.6122 | Yes |
| 29 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 2320 | 1.233 | 0.5969 | No |
| 30 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 2325 | 1.231 | 0.6045 | No |
| 31 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 2849 | 0.953 | 0.5964 | No |
| 32 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 3247 | 0.779 | 0.5905 | No |
| 33 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 3978 | 0.497 | 0.5739 | No |
| 34 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 4743 | 0.362 | 0.5555 | No |
| 35 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 5516 | 0.131 | 0.5354 | No |
| 36 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 5996 | 0.000 | 0.5225 | No |
| 37 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 6969 | 0.000 | 0.4962 | No |
| 38 | EPHB4 | EPH receptor B4 [Source:HGNC Symbol;Acc:HGNC:3395] | 7115 | 0.000 | 0.4923 | No |
| 39 | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 7202 | 0.000 | 0.4900 | No |
| 40 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8563 | 0.000 | 0.4532 | No |
| 41 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 9735 | 0.000 | 0.4216 | No |
| 42 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10731 | 0.000 | 0.3947 | No |
| 43 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11802 | 0.000 | 0.3657 | No |
| 44 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12266 | 0.000 | 0.3532 | No |
| 45 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12282 | 0.000 | 0.3528 | No |
| 46 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12283 | 0.000 | 0.3528 | No |
| 47 | VIP | vasoactive intestinal peptide [Source:HGNC Symbol;Acc:HGNC:12693] | 13002 | 0.000 | 0.3334 | No |
| 48 | VIPR1 | vasoactive intestinal peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:12694] | 13212 | 0.000 | 0.3277 | No |
| 49 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13639 | 0.000 | 0.3162 | No |
| 50 | IL15RA | interleukin 15 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5978] | 14026 | 0.000 | 0.3058 | No |
| 51 | TACSTD2 | tumor associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:HGNC:11530] | 14361 | 0.000 | 0.2968 | No |
| 52 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15651 | 0.000 | 0.2619 | No |
| 53 | CD4 | CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678] | 15652 | 0.000 | 0.2619 | No |
| 54 | MST1R | macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381] | 16181 | 0.000 | 0.2476 | No |
| 55 | FGB | fibrinogen beta chain [Source:HGNC Symbol;Acc:HGNC:3662] | 16625 | 0.000 | 0.2357 | No |
| 56 | FGA | fibrinogen alpha chain [Source:HGNC Symbol;Acc:HGNC:3661] | 16626 | 0.000 | 0.2357 | No |
| 57 | FGG | fibrinogen gamma chain [Source:HGNC Symbol;Acc:HGNC:3694] | 16627 | 0.000 | 0.2357 | No |
| 58 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16883 | 0.000 | 0.2288 | No |
| 59 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17015 | 0.000 | 0.2252 | No |
| 60 | IL3 | interleukin 3 [Source:HGNC Symbol;Acc:HGNC:6011] | 17696 | 0.000 | 0.2069 | No |
| 61 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17813 | 0.000 | 0.2037 | No |
| 62 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 19022 | 0.000 | 0.1711 | No |
| 63 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19491 | 0.000 | 0.1584 | No |
| 64 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 21464 | 0.000 | 0.1051 | No |
| 65 | FGF4 | fibroblast growth factor 4 [Source:HGNC Symbol;Acc:HGNC:3682] | 22446 | 0.000 | 0.0786 | No |
| 66 | REG1B | regenerating family member 1 beta [Source:HGNC Symbol;Acc:HGNC:9952] | 23487 | 0.000 | 0.0505 | No |
| 67 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 24244 | 0.000 | 0.0300 | No |
| 68 | PTN | pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] | 24817 | 0.000 | 0.0146 | No |
| 69 | EDNRA | endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] | 26734 | 0.000 | -0.0372 | No |
| 70 | EGR4 | early growth response 4 [Source:HGNC Symbol;Acc:HGNC:3241] | 27120 | 0.000 | -0.0476 | No |
| 71 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 27862 | 0.000 | -0.0677 | No |
| 72 | SLAMF1 | signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903] | 27897 | 0.000 | -0.0686 | No |
| 73 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 28023 | 0.000 | -0.0720 | No |
| 74 | CD8A | CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706] | 28024 | 0.000 | -0.0720 | No |
| 75 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 28321 | -0.060 | -0.0796 | No |
| 76 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 29080 | -0.245 | -0.0985 | No |
| 77 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 29242 | -0.296 | -0.1010 | No |
| 78 | GRN | granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601] | 29577 | -0.380 | -0.1077 | No |
| 79 | CRIP1 | cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360] | 31107 | -0.795 | -0.1441 | No |
| 80 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 31493 | -0.915 | -0.1487 | No |
| 81 | INSIG1 | insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] | 31908 | -1.060 | -0.1533 | No |
| 82 | MAPRE2 | microtubule associated protein RP/EB family member 2 [Source:HGNC Symbol;Acc:HGNC:6891] | 32994 | -1.447 | -0.1736 | No |
| 83 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 33510 | -1.669 | -0.1770 | No |
| 84 | LRP1 | LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692] | 34022 | -1.926 | -0.1788 | No |
| 85 | TGFB3 | transforming growth factor beta 3 [Source:HGNC Symbol;Acc:HGNC:11769] | 34331 | -2.104 | -0.1740 | No |
| 86 | CREG1 | cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351] | 34544 | -2.193 | -0.1660 | No |
| 87 | SFN | stratifin [Source:HGNC Symbol;Acc:HGNC:10773] | 34608 | -2.237 | -0.1537 | No |
| 88 | CSRP2 | cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] | 34759 | -2.319 | -0.1432 | No |
| 89 | EPS8 | epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420] | 34848 | -2.389 | -0.1306 | No |
| 90 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 34883 | -2.408 | -0.1165 | No |
| 91 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 35289 | -2.679 | -0.1107 | No |
| 92 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35325 | -2.700 | -0.0947 | No |
| 93 | ZFP36L2 | ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108] | 35453 | -2.801 | -0.0806 | No |
| 94 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 35558 | -2.897 | -0.0653 | No |
| 95 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 35568 | -2.909 | -0.0474 | No |
| 96 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 35599 | -2.946 | -0.0297 | No |
| 97 | GAS6 | growth arrest specific 6 [Source:HGNC Symbol;Acc:HGNC:4168] | 35713 | -3.053 | -0.0137 | No |
| 98 | BCAR1 | BCAR1 scaffold protein, Cas family member [Source:HGNC Symbol;Acc:HGNC:971] | 36156 | -3.491 | -0.0038 | No |
| 99 | RUNX3 | RUNX family transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473] | 36977 | -4.635 | 0.0031 | No |
