Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_208 |
| Enrichment Score (ES) | 0.57802296 |
| Normalized Enrichment Score (NES) | 1.5070909 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.2300478 |
| FWER p-Value | 0.943 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 23 | 4.958 | 0.0331 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 49 | 4.852 | 0.0654 | Yes |
| 3 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 55 | 4.827 | 0.0981 | Yes |
| 4 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 59 | 4.819 | 0.1308 | Yes |
| 5 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 75 | 4.745 | 0.1626 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 119 | 4.515 | 0.1922 | Yes |
| 7 | NLRC5 | NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933] | 140 | 4.379 | 0.2214 | Yes |
| 8 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 154 | 4.328 | 0.2505 | Yes |
| 9 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 162 | 4.295 | 0.2795 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 238 | 4.000 | 0.3047 | Yes |
| 11 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 281 | 3.833 | 0.3296 | Yes |
| 12 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 305 | 3.784 | 0.3547 | Yes |
| 13 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 307 | 3.781 | 0.3804 | Yes |
| 14 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 419 | 3.394 | 0.4004 | Yes |
| 15 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 422 | 3.383 | 0.4234 | Yes |
| 16 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 536 | 3.138 | 0.4417 | Yes |
| 17 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 582 | 3.032 | 0.4611 | Yes |
| 18 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 654 | 2.858 | 0.4786 | Yes |
| 19 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 828 | 2.609 | 0.4916 | Yes |
| 20 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 900 | 2.491 | 0.5067 | Yes |
| 21 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 944 | 2.415 | 0.5219 | Yes |
| 22 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 1025 | 2.276 | 0.5352 | Yes |
| 23 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 1173 | 2.075 | 0.5454 | Yes |
| 24 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 1411 | 1.896 | 0.5518 | Yes |
| 25 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 1576 | 1.741 | 0.5592 | Yes |
| 26 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 1912 | 1.458 | 0.5601 | Yes |
| 27 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 2072 | 1.379 | 0.5652 | Yes |
| 28 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2196 | 1.300 | 0.5707 | Yes |
| 29 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 2608 | 1.072 | 0.5669 | Yes |
| 30 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 2684 | 1.028 | 0.5718 | Yes |
| 31 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 2848 | 0.954 | 0.5739 | Yes |
| 32 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2927 | 0.918 | 0.5780 | Yes |
| 33 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 4391 | 0.473 | 0.5417 | No |
| 34 | KLF6 | Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] | 4743 | 0.362 | 0.5346 | No |
| 35 | ZNF292 | zinc finger protein 292 [Source:HGNC Symbol;Acc:HGNC:18410] | 5268 | 0.196 | 0.5218 | No |
| 36 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 5929 | 0.008 | 0.5040 | No |
| 37 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6019 | 0.000 | 0.5016 | No |
| 38 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 6080 | 0.000 | 0.5000 | No |
| 39 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6488 | 0.000 | 0.4890 | No |
| 40 | SELP | selectin P [Source:HGNC Symbol;Acc:HGNC:10721] | 6830 | 0.000 | 0.4797 | No |
| 41 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7519 | 0.000 | 0.4611 | No |
| 42 | CD200 | CD200 molecule [Source:HGNC Symbol;Acc:HGNC:7203] | 7830 | 0.000 | 0.4527 | No |
| 43 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8785 | 0.000 | 0.4269 | No |
| 44 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 8976 | 0.000 | 0.4218 | No |
| 45 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9583 | 0.000 | 0.4054 | No |
| 46 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9653 | 0.000 | 0.4035 | No |
| 47 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9658 | 0.000 | 0.4034 | No |
| 48 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9804 | 0.000 | 0.3995 | No |
| 49 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10306 | 0.000 | 0.3859 | No |
| 50 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10846 | 0.000 | 0.3714 | No |
| 51 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 11973 | 0.000 | 0.3409 | No |
| 52 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12046 | 0.000 | 0.3390 | No |
| 53 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12250 | 0.000 | 0.3335 | No |
| 54 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12254 | 0.000 | 0.3334 | No |
| 55 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12319 | 0.000 | 0.3317 | No |
| 56 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 12983 | 0.000 | 0.3137 | No |
| 57 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13279 | 0.000 | 0.3057 | No |
| 58 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13709 | 0.000 | 0.2941 | No |
| 59 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13734 | 0.000 | 0.2935 | No |
| 60 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14514 | 0.000 | 0.2724 | No |
| 61 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 15002 | 0.000 | 0.2592 | No |
| 62 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 15369 | 0.000 | 0.2493 | No |
| 63 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15526 | 0.000 | 0.2451 | No |
| 64 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15651 | 0.000 | 0.2418 | No |
| 65 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15768 | 0.000 | 0.2386 | No |
| 66 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 16088 | 0.000 | 0.2300 | No |
| 67 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16102 | 0.000 | 0.2296 | No |
| 68 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16134 | 0.000 | 0.2288 | No |
| 69 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16449 | 0.000 | 0.2203 | No |
| 70 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16460 | 0.000 | 0.2200 | No |
| 71 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17118 | 0.000 | 0.2023 | No |
| 72 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17777 | 0.000 | 0.1845 | No |
| 73 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18396 | 0.000 | 0.1678 | No |
| 74 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18415 | 0.000 | 0.1673 | No |
| 75 | CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene [Source:HGNC Symbol;Acc:HGNC:2098] | 18711 | 0.000 | 0.1593 | No |
| 76 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18869 | 0.000 | 0.1550 | No |
| 77 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18889 | 0.000 | 0.1545 | No |
| 78 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18895 | 0.000 | 0.1544 | No |
| 79 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18912 | 0.000 | 0.1540 | No |
| 80 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19479 | 0.000 | 0.1387 | No |
| 81 | TCF7 | transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639] | 19856 | 0.000 | 0.1285 | No |
| 82 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 20142 | 0.000 | 0.1208 | No |
| 83 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 20302 | 0.000 | 0.1165 | No |
| 84 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 20427 | 0.000 | 0.1131 | No |
| 85 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 20646 | 0.000 | 0.1072 | No |
| 86 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 22035 | 0.000 | 0.0697 | No |
| 87 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 22044 | 0.000 | 0.0695 | No |
| 88 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 22589 | 0.000 | 0.0547 | No |
| 89 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 22888 | 0.000 | 0.0467 | No |
| 90 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 25359 | 0.000 | -0.0201 | No |
| 91 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 25573 | 0.000 | -0.0259 | No |
| 92 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 27260 | 0.000 | -0.0715 | No |
| 93 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 27311 | 0.000 | -0.0729 | No |
| 94 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27823 | 0.000 | -0.0867 | No |
| 95 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 27923 | 0.000 | -0.0894 | No |
| 96 | CD48 | CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683] | 27952 | 0.000 | -0.0901 | No |
| 97 | CD8B | CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707] | 28023 | 0.000 | -0.0920 | No |
| 98 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 28158 | -0.012 | -0.0956 | No |
| 99 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 29080 | -0.245 | -0.1188 | No |
| 100 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 29405 | -0.341 | -0.1252 | No |
| 101 | MCU | mitochondrial calcium uniporter [Source:HGNC Symbol;Acc:HGNC:23526] | 29473 | -0.360 | -0.1246 | No |
| 102 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 30014 | -0.504 | -0.1358 | No |
| 103 | USP30 | ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065] | 30760 | -0.697 | -0.1512 | No |
| 104 | KCNA3 | potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221] | 31113 | -0.796 | -0.1553 | No |
| 105 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 31651 | -0.974 | -0.1632 | No |
| 106 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 31796 | -1.025 | -0.1601 | No |
| 107 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 31913 | -1.063 | -0.1561 | No |
| 108 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 32464 | -1.232 | -0.1626 | No |
| 109 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32691 | -1.316 | -0.1597 | No |
| 110 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32753 | -1.341 | -0.1522 | No |
| 111 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33373 | -1.606 | -0.1581 | No |
| 112 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 33994 | -1.910 | -0.1619 | No |
| 113 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 34746 | -2.313 | -0.1664 | No |
| 114 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35184 | -2.627 | -0.1604 | No |
| 115 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 35231 | -2.671 | -0.1435 | No |
| 116 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35416 | -2.768 | -0.1296 | No |
| 117 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 35766 | -3.107 | -0.1180 | No |
| 118 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36100 | -3.438 | -0.1036 | No |
| 119 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36139 | -3.470 | -0.0810 | No |
| 120 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 36287 | -3.612 | -0.0604 | No |
| 121 | SLC40A1 | solute carrier family 40 member 1 [Source:HGNC Symbol;Acc:HGNC:10909] | 36339 | -3.683 | -0.0368 | No |
| 122 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36635 | -4.040 | -0.0173 | No |
| 123 | S1PR1 | sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165] | 36837 | -4.349 | 0.0068 | No |
