Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_345 |
| Enrichment Score (ES) | 0.64725715 |
| Normalized Enrichment Score (NES) | 1.7126198 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.056959532 |
| FWER p-Value | 0.26 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 17 | 4.971 | 0.0304 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 23 | 4.958 | 0.0611 | Yes |
| 3 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 49 | 4.852 | 0.0905 | Yes |
| 4 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 57 | 4.823 | 0.1203 | Yes |
| 5 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 59 | 4.819 | 0.1502 | Yes |
| 6 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 66 | 4.776 | 0.1797 | Yes |
| 7 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 119 | 4.515 | 0.2063 | Yes |
| 8 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 154 | 4.328 | 0.2322 | Yes |
| 9 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 162 | 4.295 | 0.2587 | Yes |
| 10 | PELI1 | pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827] | 238 | 4.000 | 0.2815 | Yes |
| 11 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 267 | 3.874 | 0.3048 | Yes |
| 12 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 271 | 3.864 | 0.3288 | Yes |
| 13 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 281 | 3.833 | 0.3523 | Yes |
| 14 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 305 | 3.784 | 0.3752 | Yes |
| 15 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 307 | 3.781 | 0.3986 | Yes |
| 16 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 419 | 3.394 | 0.4167 | Yes |
| 17 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 422 | 3.383 | 0.4377 | Yes |
| 18 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 431 | 3.336 | 0.4582 | Yes |
| 19 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 536 | 3.138 | 0.4748 | Yes |
| 20 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 556 | 3.095 | 0.4935 | Yes |
| 21 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 567 | 3.066 | 0.5123 | Yes |
| 22 | RRP15 | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] | 582 | 3.032 | 0.5308 | Yes |
| 23 | AQP9 | aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643] | 654 | 2.858 | 0.5466 | Yes |
| 24 | CD79B | CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699] | 818 | 2.619 | 0.5584 | Yes |
| 25 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 900 | 2.491 | 0.5717 | Yes |
| 26 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 944 | 2.415 | 0.5855 | Yes |
| 27 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 1025 | 2.276 | 0.5975 | Yes |
| 28 | PPP1R16B | protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] | 1173 | 2.075 | 0.6064 | Yes |
| 29 | ZNF436 | zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] | 1395 | 1.919 | 0.6124 | Yes |
| 30 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 1411 | 1.896 | 0.6237 | Yes |
| 31 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 1912 | 1.458 | 0.6193 | Yes |
| 32 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 2022 | 1.414 | 0.6251 | Yes |
| 33 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2196 | 1.300 | 0.6285 | Yes |
| 34 | BLNK | B cell linker [Source:HGNC Symbol;Acc:HGNC:14211] | 2361 | 1.213 | 0.6316 | Yes |
| 35 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 2608 | 1.072 | 0.6316 | Yes |
| 36 | FOXP1 | forkhead box P1 [Source:HGNC Symbol;Acc:HGNC:3823] | 2684 | 1.028 | 0.6359 | Yes |
| 37 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 2761 | 0.998 | 0.6401 | Yes |
| 38 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 2848 | 0.954 | 0.6437 | Yes |
| 39 | CCDC186 | coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349] | 2927 | 0.918 | 0.6473 | Yes |
| 40 | UNKL | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] | 3954 | 0.505 | 0.6226 | No |
| 41 | FCRL2 | Fc receptor like 2 [Source:HGNC Symbol;Acc:HGNC:14875] | 4164 | 0.473 | 0.6199 | No |
| 42 | BANK1 | B cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:HGNC:18233] | 4391 | 0.473 | 0.6167 | No |
| 43 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 5211 | 0.211 | 0.5959 | No |
| 44 | UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [Source:HGNC Symbol;Acc:HGNC:12638] | 5929 | 0.008 | 0.5766 | No |
| 45 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6019 | 0.000 | 0.5742 | No |
| 46 | HVCN1 | hydrogen voltage gated channel 1 [Source:HGNC Symbol;Acc:HGNC:28240] | 6080 | 0.000 | 0.5725 | No |
| 47 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 6488 | 0.000 | 0.5615 | No |
| 48 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 6831 | 0.000 | 0.5523 | No |
| 49 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8785 | 0.000 | 0.4994 | No |
| 50 | TNFRSF25 | TNF receptor superfamily member 25 [Source:HGNC Symbol;Acc:HGNC:11910] | 8976 | 0.000 | 0.4943 | No |
| 51 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9379 | 0.000 | 0.4834 | No |
| 52 | KCNQ5 | potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299] | 9583 | 0.000 | 0.4779 | No |
| 53 | ADAM19 | ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197] | 9653 | 0.000 | 0.4761 | No |
| 54 | CARD16 | caspase recruitment domain family member 16 [Source:HGNC Symbol;Acc:HGNC:33701] | 9658 | 0.000 | 0.4760 | No |
| 55 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 9804 | 0.000 | 0.4720 | No |
| 56 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 10306 | 0.000 | 0.4585 | No |
| 57 | MS4A1 | membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315] | 10846 | 0.000 | 0.4439 | No |
| 58 | NEK11 | NIMA related kinase 11 [Source:HGNC Symbol;Acc:HGNC:18593] | 12046 | 0.000 | 0.4115 | No |
| 59 | UNC79 | unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966] | 12250 | 0.000 | 0.4060 | No |
| 60 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12254 | 0.000 | 0.4059 | No |
| 61 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12283 | 0.000 | 0.4051 | No |
| 62 | IGKC | immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716] | 12319 | 0.000 | 0.4042 | No |
| 63 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 12903 | 0.000 | 0.3884 | No |
| 64 | CNRIP1 | cannabinoid receptor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24546] | 12983 | 0.000 | 0.3863 | No |
| 65 | TPTE2 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:HGNC:17299] | 13709 | 0.000 | 0.3667 | No |
| 66 | PNMA8A | PNMA family member 8A [Source:HGNC Symbol;Acc:HGNC:25578] | 14514 | 0.000 | 0.3449 | No |
| 67 | KIAA0753 | KIAA0753 [Source:HGNC Symbol;Acc:HGNC:29110] | 15002 | 0.000 | 0.3317 | No |
| 68 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 15369 | 0.000 | 0.3218 | No |
| 69 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15526 | 0.000 | 0.3176 | No |
| 70 | CD2 | CD2 molecule [Source:HGNC Symbol;Acc:HGNC:1639] | 15651 | 0.000 | 0.3143 | No |
| 71 | HLA-DMB | major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935] | 16088 | 0.000 | 0.3025 | No |
| 72 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16102 | 0.000 | 0.3021 | No |
| 73 | HLA-DRA | major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947] | 16134 | 0.000 | 0.3013 | No |
| 74 | MST1L | macrophage stimulating 1 like [Source:HGNC Symbol;Acc:HGNC:7390] | 16182 | 0.000 | 0.3000 | No |
| 75 | TREM1 | triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760] | 16449 | 0.000 | 0.2928 | No |
| 76 | IL3RA | interleukin 3 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6012] | 16460 | 0.000 | 0.2925 | No |
| 77 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527] | 17118 | 0.000 | 0.2748 | No |
| 78 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17777 | 0.000 | 0.2570 | No |
| 79 | FCRLA | Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504] | 17778 | 0.000 | 0.2570 | No |
| 80 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18396 | 0.000 | 0.2403 | No |
| 81 | IGLJ3 | immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865] | 18415 | 0.000 | 0.2398 | No |
| 82 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18444 | 0.000 | 0.2390 | No |
| 83 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:HGNC:4938] | 18869 | 0.000 | 0.2276 | No |
| 84 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940] | 18889 | 0.000 | 0.2270 | No |
| 85 | MAL | mal, T cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817] | 18912 | 0.000 | 0.2264 | No |
| 86 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19479 | 0.000 | 0.2111 | No |
| 87 | KLRK1 | killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788] | 20302 | 0.000 | 0.1889 | No |
| 88 | UCP1 | uncoupling protein 1 [Source:HGNC Symbol;Acc:HGNC:12517] | 20337 | 0.000 | 0.1880 | No |
| 89 | DEFA1 | defensin alpha 1 [Source:HGNC Symbol;Acc:HGNC:2761] | 20427 | 0.000 | 0.1856 | No |
| 90 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 21307 | 0.000 | 0.1618 | No |
| 91 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 22035 | 0.000 | 0.1421 | No |
| 92 | HBA2 | hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824] | 22044 | 0.000 | 0.1419 | No |
| 93 | CD79A | CD79a molecule [Source:HGNC Symbol;Acc:HGNC:1698] | 22589 | 0.000 | 0.1272 | No |
| 94 | STK31 | serine/threonine kinase 31 [Source:HGNC Symbol;Acc:HGNC:11407] | 22888 | 0.000 | 0.1191 | No |
| 95 | SPIB | Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242] | 23441 | 0.000 | 0.1042 | No |
| 96 | SLC22A23 | solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106] | 23862 | 0.000 | 0.0928 | No |
| 97 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 25359 | 0.000 | 0.0524 | No |
| 98 | UNC5D | unc-5 netrin receptor D [Source:HGNC Symbol;Acc:HGNC:18634] | 25573 | 0.000 | 0.0466 | No |
| 99 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 27311 | 0.000 | -0.0004 | No |
| 100 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27823 | 0.000 | -0.0142 | No |
| 101 | CD19 | CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633] | 27890 | 0.000 | -0.0160 | No |
| 102 | CD27 | CD27 molecule [Source:HGNC Symbol;Acc:HGNC:11922] | 27912 | 0.000 | -0.0166 | No |
| 103 | CD3D | CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673] | 27923 | 0.000 | -0.0168 | No |
| 104 | POLR3B | RNA polymerase III subunit B [Source:HGNC Symbol;Acc:HGNC:30348] | 28158 | -0.012 | -0.0231 | No |
| 105 | CD5 | CD5 molecule [Source:HGNC Symbol;Acc:HGNC:1685] | 29080 | -0.245 | -0.0465 | No |
| 106 | TXLNGY | taxilin gamma pseudogene, Y-linked [Source:HGNC Symbol;Acc:HGNC:18473] | 29405 | -0.341 | -0.0531 | No |
| 107 | P2RY10 | P2Y receptor family member 10 [Source:HGNC Symbol;Acc:HGNC:19906] | 30014 | -0.504 | -0.0665 | No |
| 108 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 30285 | -0.551 | -0.0703 | No |
| 109 | CD37 | CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666] | 31173 | -0.816 | -0.0893 | No |
| 110 | AXIN1 | axin 1 [Source:HGNC Symbol;Acc:HGNC:903] | 31651 | -0.974 | -0.0961 | No |
| 111 | LIMD2 | LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142] | 31796 | -1.025 | -0.0936 | No |
| 112 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944] | 31913 | -1.063 | -0.0902 | No |
| 113 | RUBCNL | rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420] | 32181 | -1.169 | -0.0902 | No |
| 114 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 32464 | -1.232 | -0.0901 | No |
| 115 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32753 | -1.341 | -0.0896 | No |
| 116 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 33373 | -1.606 | -0.0964 | No |
| 117 | UNC13B | unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] | 34414 | -2.127 | -0.1113 | No |
| 118 | THBS1 | thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785] | 34746 | -2.313 | -0.1059 | No |
| 119 | ABTB1 | ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275] | 35231 | -2.671 | -0.1024 | No |
| 120 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35416 | -2.768 | -0.0902 | No |
| 121 | HLA-DMA | major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934] | 35766 | -3.107 | -0.0803 | No |
| 122 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36100 | -3.438 | -0.0680 | No |
| 123 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36139 | -3.470 | -0.0475 | No |
| 124 | TTC30A | tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853] | 36287 | -3.612 | -0.0290 | No |
| 125 | IGHM | immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541] | 36635 | -4.040 | -0.0133 | No |
| 126 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36698 | -4.122 | 0.0106 | No |
