Fig 1: Enrichment plot: MODULE_562
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_562 |
| Enrichment Score (ES) | 0.7901574 |
| Normalized Enrichment Score (NES) | 1.5205106 |
| Nominal p-value | 0.029900333 |
| FDR q-value | 0.23246078 |
| FWER p-Value | 0.929 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 71 | 4.757 | 0.1444 | Yes |
| 2 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 73 | 4.750 | 0.2905 | Yes |
| 3 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 105 | 4.607 | 0.4313 | Yes |
| 4 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 127 | 4.445 | 0.5675 | Yes |
| 5 | MMP14 | matrix metallopeptidase 14 [Source:HGNC Symbol;Acc:HGNC:7160] | 598 | 2.990 | 0.6468 | Yes |
| 6 | MMP2 | matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166] | 643 | 2.885 | 0.7343 | Yes |
| 7 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 1667 | 1.673 | 0.7582 | Yes |
| 8 | BMP1 | bone morphogenetic protein 1 [Source:HGNC Symbol;Acc:HGNC:1067] | 2062 | 1.385 | 0.7902 | Yes |
| 9 | MMP12 | matrix metallopeptidase 12 [Source:HGNC Symbol;Acc:HGNC:7158] | 3951 | 0.507 | 0.7548 | No |
| 10 | ADAM9 | ADAM metallopeptidase domain 9 [Source:HGNC Symbol;Acc:HGNC:216] | 4724 | 0.369 | 0.7453 | No |
| 11 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9655 | 0.000 | 0.6123 | No |
| 12 | TIMP3 | TIMP metallopeptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:11822] | 17094 | 0.000 | 0.4117 | No |
| 13 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 19125 | 0.000 | 0.3569 | No |
| 14 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19128 | 0.000 | 0.3569 | No |
| 15 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 19132 | 0.000 | 0.3568 | No |
| 16 | CHIT1 | chitinase 1 [Source:HGNC Symbol;Acc:HGNC:1936] | 24516 | 0.000 | 0.2116 | No |
| 17 | MMP11 | matrix metallopeptidase 11 [Source:HGNC Symbol;Acc:HGNC:7157] | 25636 | 0.000 | 0.1814 | No |
| 18 | MMP15 | matrix metallopeptidase 15 [Source:HGNC Symbol;Acc:HGNC:7161] | 28808 | -0.185 | 0.1016 | No |
| 19 | PEPD | peptidase D [Source:HGNC Symbol;Acc:HGNC:8840] | 29772 | -0.435 | 0.0890 | No |
| 20 | ADAM10 | ADAM metallopeptidase domain 10 [Source:HGNC Symbol;Acc:HGNC:188] | 33394 | -1.620 | 0.0411 | No |
| 21 | TIMP2 | TIMP metallopeptidase inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11821] | 33986 | -1.905 | 0.0837 | No |
