Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.75496984 |
| Normalized Enrichment Score (NES) | 1.8777738 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.009289296 |
| FWER p-Value | 0.012 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0467 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 26 | 4.953 | 0.0925 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 28 | 4.948 | 0.1388 | Yes |
| 4 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 40 | 4.912 | 0.1845 | Yes |
| 5 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.2278 | Yes |
| 6 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 84 | 4.682 | 0.2715 | Yes |
| 7 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 125 | 4.464 | 0.3122 | Yes |
| 8 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 129 | 4.432 | 0.3536 | Yes |
| 9 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 209 | 4.082 | 0.3897 | Yes |
| 10 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 262 | 3.886 | 0.4247 | Yes |
| 11 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 290 | 3.811 | 0.4597 | Yes |
| 12 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 320 | 3.725 | 0.4938 | Yes |
| 13 | FPR2 | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827] | 370 | 3.580 | 0.5260 | Yes |
| 14 | AOAH | acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548] | 401 | 3.449 | 0.5574 | Yes |
| 15 | ADORA2A | adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263] | 407 | 3.434 | 0.5895 | Yes |
| 16 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 536 | 3.138 | 0.6154 | Yes |
| 17 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 629 | 2.929 | 0.6403 | Yes |
| 18 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 952 | 2.396 | 0.6541 | Yes |
| 19 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1087 | 2.179 | 0.6709 | Yes |
| 20 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 1367 | 1.957 | 0.6817 | Yes |
| 21 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1375 | 1.947 | 0.6997 | Yes |
| 22 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 1492 | 1.820 | 0.7136 | Yes |
| 23 | TIRAP | TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192] | 1724 | 1.614 | 0.7225 | Yes |
| 24 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 2180 | 1.310 | 0.7225 | Yes |
| 25 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 2190 | 1.306 | 0.7344 | Yes |
| 26 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2196 | 1.300 | 0.7465 | Yes |
| 27 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 2312 | 1.239 | 0.7550 | Yes |
| 28 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 2849 | 0.953 | 0.7494 | No |
| 29 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 2980 | 0.892 | 0.7543 | No |
| 30 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 4405 | 0.470 | 0.7202 | No |
| 31 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 4635 | 0.396 | 0.7177 | No |
| 32 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 5182 | 0.219 | 0.7050 | No |
| 33 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 5495 | 0.135 | 0.6978 | No |
| 34 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 5997 | 0.000 | 0.6843 | No |
| 35 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 5998 | 0.000 | 0.6843 | No |
| 36 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6018 | 0.000 | 0.6838 | No |
| 37 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6019 | 0.000 | 0.6838 | No |
| 38 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6021 | 0.000 | 0.6838 | No |
| 39 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6028 | 0.000 | 0.6836 | No |
| 40 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6030 | 0.000 | 0.6836 | No |
| 41 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6032 | 0.000 | 0.6835 | No |
| 42 | AOX1 | aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553] | 6227 | 0.000 | 0.6783 | No |
| 43 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8248 | 0.000 | 0.6237 | No |
| 44 | LY75 | lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] | 8923 | 0.000 | 0.6055 | No |
| 45 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 8952 | 0.000 | 0.6048 | No |
| 46 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10488 | 0.000 | 0.5633 | No |
| 47 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11486 | 0.000 | 0.5363 | No |
| 48 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 12152 | 0.000 | 0.5184 | No |
| 49 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 12612 | 0.000 | 0.5060 | No |
| 50 | C4B | complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324] | 15531 | 0.000 | 0.4271 | No |
| 51 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15800 | 0.000 | 0.4199 | No |
| 52 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16018 | 0.000 | 0.4140 | No |
| 53 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16708 | 0.000 | 0.3954 | No |
| 54 | MGLL | monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038] | 17106 | 0.000 | 0.3847 | No |
| 55 | IL9 | interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029] | 17700 | 0.000 | 0.3687 | No |
| 56 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 17954 | 0.000 | 0.3618 | No |
| 57 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18645 | 0.000 | 0.3432 | No |
| 58 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18895 | 0.000 | 0.3365 | No |
| 59 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18934 | 0.000 | 0.3354 | No |
| 60 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18935 | 0.000 | 0.3354 | No |
| 61 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19356 | 0.000 | 0.3241 | No |
| 62 | CXCR2 | C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027] | 19398 | 0.000 | 0.3230 | No |
| 63 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19477 | 0.000 | 0.3209 | No |
| 64 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19479 | 0.000 | 0.3208 | No |
| 65 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19482 | 0.000 | 0.3208 | No |
| 66 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19491 | 0.000 | 0.3206 | No |
| 67 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19494 | 0.000 | 0.3205 | No |
| 68 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19496 | 0.000 | 0.3205 | No |
| 69 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 26956 | 0.000 | 0.1189 | No |
| 70 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27821 | 0.000 | 0.0956 | No |
| 71 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27823 | 0.000 | 0.0956 | No |
| 72 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 27899 | 0.000 | 0.0935 | No |
| 73 | ABCF1 | ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70] | 28797 | -0.182 | 0.0710 | No |
| 74 | NFATC4 | nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778] | 30397 | -0.584 | 0.0333 | No |
| 75 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 30662 | -0.672 | 0.0324 | No |
| 76 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 32818 | -1.362 | -0.0130 | No |
| 77 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 33225 | -1.544 | -0.0095 | No |
| 78 | AGER | advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320] | 33762 | -1.786 | -0.0073 | No |
| 79 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 34720 | -2.299 | -0.0116 | No |
| 80 | ALOX5AP | arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436] | 35838 | -3.176 | -0.0121 | No |
| 81 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 37054 | -4.898 | 0.0010 | No |
