Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_HOMOLOGOUS_CHROMOSOME_SEGREGATION |
| Enrichment Score (ES) | -0.81147546 |
| Normalized Enrichment Score (NES) | -1.5939332 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.082599744 |
| FWER p-Value | 0.69 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 3630 | 0.630 | -0.0876 | No |
| 2 | RNF212 | ring finger protein 212 [Source:HGNC Symbol;Acc:HGNC:27729] | 4273 | 0.473 | -0.0971 | No |
| 3 | ANKRD31 | ankyrin repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:26853] | 7362 | 0.000 | -0.1805 | No |
| 4 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7519 | 0.000 | -0.1847 | No |
| 5 | PTTG2 | pituitary tumor-transforming 2 [Source:HGNC Symbol;Acc:HGNC:9691] | 7590 | 0.000 | -0.1866 | No |
| 6 | RAD21L1 | RAD21 cohesin complex component like 1 [Source:HGNC Symbol;Acc:HGNC:16271] | 7747 | 0.000 | -0.1908 | No |
| 7 | C1orf146 | chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:HGNC:24032] | 9855 | 0.000 | -0.2477 | No |
| 8 | MEIOC | meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670] | 10524 | 0.000 | -0.2657 | No |
| 9 | RNF212B | ring finger protein 212B [Source:HGNC Symbol;Acc:HGNC:20438] | 11407 | 0.000 | -0.2895 | No |
| 10 | IHO1 | interactor of HORMAD1 1 [Source:HGNC Symbol;Acc:HGNC:27945] | 12599 | 0.000 | -0.3217 | No |
| 11 | MEIKIN | meiotic kinetochore factor [Source:HGNC Symbol;Acc:HGNC:51253] | 12663 | 0.000 | -0.3234 | No |
| 12 | TERB1 | telomere repeat binding bouquet formation protein 1 [Source:HGNC Symbol;Acc:HGNC:26675] | 12963 | 0.000 | -0.3315 | No |
| 13 | TERB2 | telomere repeat binding bouquet formation protein 2 [Source:HGNC Symbol;Acc:HGNC:28520] | 12964 | 0.000 | -0.3315 | No |
| 14 | REC8 | REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879] | 13542 | 0.000 | -0.3471 | No |
| 15 | TEX11 | testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733] | 15149 | 0.000 | -0.3904 | No |
| 16 | TEX12 | testis expressed 12 [Source:HGNC Symbol;Acc:HGNC:11734] | 15150 | 0.000 | -0.3904 | No |
| 17 | TEX15 | testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738] | 15151 | 0.000 | -0.3904 | No |
| 18 | MEI4 | meiotic double-stranded break formation protein 4 [Source:HGNC Symbol;Acc:HGNC:43638] | 16327 | 0.000 | -0.4222 | No |
| 19 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16854 | 0.000 | -0.4364 | No |
| 20 | SYCE3 | synaptonemal complex central element protein 3 [Source:HGNC Symbol;Acc:HGNC:35245] | 16941 | 0.000 | -0.4387 | No |
| 21 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 16942 | 0.000 | -0.4387 | No |
| 22 | SYCE1 | synaptonemal complex central element protein 1 [Source:HGNC Symbol;Acc:HGNC:28852] | 16943 | 0.000 | -0.4387 | No |
| 23 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17841 | 0.000 | -0.4629 | No |
| 24 | CCNB1IP1 | cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437] | 18311 | 0.000 | -0.4756 | No |
| 25 | PTTG3P | pituitary tumor-transforming 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:13422] | 18498 | 0.000 | -0.4806 | No |
| 26 | P3H4 | prolyl 3-hydroxylase family member 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:16946] | 18575 | 0.000 | -0.4826 | No |
| 27 | SPO11 | SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250] | 19485 | 0.000 | -0.5072 | No |
| 28 | C14orf39 | chromosome 14 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:19849] | 19730 | 0.000 | -0.5138 | No |
| 29 | MAJIN | membrane anchored junction protein [Source:HGNC Symbol;Acc:HGNC:27441] | 21861 | 0.000 | -0.5713 | No |
| 30 | SPATA22 | spermatogenesis associated 22 [Source:HGNC Symbol;Acc:HGNC:30705] | 22008 | 0.000 | -0.5752 | No |
| 31 | FMN2 | formin 2 [Source:HGNC Symbol;Acc:HGNC:14074] | 24256 | 0.000 | -0.6359 | No |
| 32 | MAEL | maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:HGNC:25929] | 24328 | 0.000 | -0.6378 | No |
| 33 | MSH4 | mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327] | 25676 | 0.000 | -0.6742 | No |
| 34 | HORMAD1 | HORMA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25245] | 26474 | 0.000 | -0.6957 | No |
| 35 | SYCE1L | synaptonemal complex central element protein 1 like [Source:HGNC Symbol;Acc:HGNC:37236] | 27585 | 0.000 | -0.7257 | No |
| 36 | MEIOB | meiosis specific with OB-fold [Source:HGNC Symbol;Acc:HGNC:28569] | 28721 | -0.160 | -0.7537 | No |
| 37 | BAG6 | BAG cochaperone 6 [Source:HGNC Symbol;Acc:HGNC:13919] | 28966 | -0.228 | -0.7565 | No |
| 38 | SIRT7 | sirtuin 7 [Source:HGNC Symbol;Acc:HGNC:14935] | 31002 | -0.770 | -0.7987 | Yes |
| 39 | CENPC | centromere protein C [Source:HGNC Symbol;Acc:HGNC:1854] | 31024 | -0.780 | -0.7863 | Yes |
| 40 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 31867 | -1.046 | -0.7917 | Yes |
| 41 | NDC1 | NDC1 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:25525] | 32592 | -1.264 | -0.7903 | Yes |
| 42 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 32691 | -1.316 | -0.7712 | Yes |
| 43 | SYCP2 | synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490] | 33048 | -1.474 | -0.7563 | Yes |
| 44 | KASH5 | KASH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26520] | 33396 | -1.622 | -0.7388 | Yes |
| 45 | ATM | ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795] | 33775 | -1.796 | -0.7193 | Yes |
| 46 | MLH3 | mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128] | 34199 | -2.026 | -0.6971 | Yes |
| 47 | PRDM9 | PR/SET domain 9 [Source:HGNC Symbol;Acc:HGNC:13994] | 34459 | -2.128 | -0.6688 | Yes |
| 48 | RAD21 | RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811] | 34850 | -2.390 | -0.6397 | Yes |
| 49 | BRIP1 | BRCA1 interacting protein C-terminal helicase 1 [Source:HGNC Symbol;Acc:HGNC:20473] | 35005 | -2.491 | -0.6026 | Yes |
| 50 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35157 | -2.606 | -0.5635 | Yes |
| 51 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 35408 | -2.762 | -0.5244 | Yes |
| 52 | ZCWPW1 | zinc finger CW-type and PWWP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23486] | 35684 | -3.053 | -0.4813 | Yes |
| 53 | FANCD2 | FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585] | 36074 | -3.406 | -0.4353 | Yes |
| 54 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36079 | -3.411 | -0.3789 | Yes |
| 55 | AGO4 | argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424] | 36192 | -3.524 | -0.3235 | Yes |
| 56 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36304 | -3.637 | -0.2662 | Yes |
| 57 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36660 | -4.066 | -0.2083 | Yes |
| 58 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36735 | -4.169 | -0.1412 | Yes |
| 59 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36917 | -4.488 | -0.0717 | Yes |
| 60 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36967 | -4.606 | 0.0033 | Yes |
