Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GOMF_CHEMOKINE_RECEPTOR_BINDING |
| Enrichment Score (ES) | 0.80606526 |
| Normalized Enrichment Score (NES) | 1.9425051 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006877996 |
| FWER p-Value | 0.026 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 10 | 4.992 | 0.1682 | Yes |
| 2 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.3259 | Yes |
| 3 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 84 | 4.682 | 0.4838 | Yes |
| 4 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 320 | 3.725 | 0.6031 | Yes |
| 5 | MSMP | microseminoprotein, prostate associated [Source:HGNC Symbol;Acc:HGNC:29663] | 1410 | 1.896 | 0.6377 | Yes |
| 6 | NARS1 | asparaginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7643] | 1561 | 1.756 | 0.6929 | Yes |
| 7 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 2180 | 1.310 | 0.7204 | Yes |
| 8 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 2190 | 1.306 | 0.7642 | Yes |
| 9 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 2312 | 1.239 | 0.8027 | Yes |
| 10 | CNIH4 | cornichon family AMPA receptor auxiliary protein 4 [Source:HGNC Symbol;Acc:HGNC:25013] | 3188 | 0.799 | 0.8061 | Yes |
| 11 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 5317 | 0.181 | 0.7547 | No |
| 12 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 5362 | 0.170 | 0.7592 | No |
| 13 | YARS1 | tyrosyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12840] | 5590 | 0.112 | 0.7569 | No |
| 14 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 5996 | 0.000 | 0.7460 | No |
| 15 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 5997 | 0.000 | 0.7460 | No |
| 16 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 5998 | 0.000 | 0.7460 | No |
| 17 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6018 | 0.000 | 0.7454 | No |
| 18 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6019 | 0.000 | 0.7454 | No |
| 19 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6021 | 0.000 | 0.7454 | No |
| 20 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6022 | 0.000 | 0.7454 | No |
| 21 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6024 | 0.000 | 0.7454 | No |
| 22 | CCL25 | C-C motif chemokine ligand 25 [Source:HGNC Symbol;Acc:HGNC:10624] | 6025 | 0.000 | 0.7454 | No |
| 23 | CCL24 | C-C motif chemokine ligand 24 [Source:HGNC Symbol;Acc:HGNC:10623] | 6026 | 0.000 | 0.7454 | No |
| 24 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6028 | 0.000 | 0.7454 | No |
| 25 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6029 | 0.000 | 0.7454 | No |
| 26 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6030 | 0.000 | 0.7454 | No |
| 27 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6032 | 0.000 | 0.7453 | No |
| 28 | CCL28 | C-C motif chemokine ligand 28 [Source:HGNC Symbol;Acc:HGNC:17700] | 6048 | 0.000 | 0.7449 | No |
| 29 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6050 | 0.000 | 0.7449 | No |
| 30 | CCL26 | C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625] | 6052 | 0.000 | 0.7449 | No |
| 31 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 6857 | 0.000 | 0.7232 | No |
| 32 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8450 | 0.000 | 0.6802 | No |
| 33 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10488 | 0.000 | 0.6251 | No |
| 34 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10731 | 0.000 | 0.6186 | No |
| 35 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 10900 | 0.000 | 0.6141 | No |
| 36 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14634 | 0.000 | 0.5132 | No |
| 37 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14635 | 0.000 | 0.5132 | No |
| 38 | XCL2 | X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646] | 15766 | 0.000 | 0.4827 | No |
| 39 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15768 | 0.000 | 0.4827 | No |
| 40 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16018 | 0.000 | 0.4760 | No |
| 41 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18895 | 0.000 | 0.3983 | No |
| 42 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18899 | 0.000 | 0.3982 | No |
| 43 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18934 | 0.000 | 0.3973 | No |
| 44 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18935 | 0.000 | 0.3973 | No |
| 45 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19477 | 0.000 | 0.3827 | No |
| 46 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19479 | 0.000 | 0.3826 | No |
| 47 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19482 | 0.000 | 0.3826 | No |
| 48 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19491 | 0.000 | 0.3824 | No |
| 49 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19493 | 0.000 | 0.3823 | No |
| 50 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19494 | 0.000 | 0.3823 | No |
| 51 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19496 | 0.000 | 0.3823 | No |
| 52 | DEFB1 | defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] | 20363 | 0.000 | 0.3589 | No |
| 53 | PF4V1 | platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862] | 24266 | 0.000 | 0.2535 | No |
| 54 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 24679 | 0.000 | 0.2424 | No |
| 55 | TFF2 | trefoil factor 2 [Source:HGNC Symbol;Acc:HGNC:11756] | 25420 | 0.000 | 0.2224 | No |
| 56 | DEFB109B | defensin beta 109B [Source:HGNC Symbol;Acc:HGNC:33469] | 25747 | 0.000 | 0.2136 | No |
| 57 | DEFB130A | defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107] | 26856 | 0.000 | 0.1837 | No |
| 58 | DEFB130B | defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814] | 26858 | 0.000 | 0.1837 | No |
| 59 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27821 | 0.000 | 0.1577 | No |
| 60 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27823 | 0.000 | 0.1577 | No |
| 61 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 27831 | 0.000 | 0.1575 | No |
| 62 | DEFB103A | defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967] | 27877 | 0.000 | 0.1562 | No |
| 63 | DEFB103B | defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702] | 27880 | 0.000 | 0.1562 | No |
| 64 | DEFB106B | defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879] | 27938 | 0.000 | 0.1547 | No |
| 65 | DEFB106A | defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088] | 27946 | 0.000 | 0.1545 | No |
| 66 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 28898 | -0.206 | 0.1357 | No |
| 67 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 30018 | -0.505 | 0.1225 | No |
| 68 | S100A14 | S100 calcium binding protein A14 [Source:HGNC Symbol;Acc:HGNC:18901] | 34209 | -2.028 | 0.0778 | No |
