Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.75422597 |
| Normalized Enrichment Score (NES) | -1.5700958 |
| Nominal p-value | 0.0011111111 |
| FDR q-value | 0.12931141 |
| FWER p-Value | 0.921 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 1920 | 1.455 | 0.0047 | No |
| 2 | PTK2B | protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:9612] | 2371 | 1.207 | 0.0396 | No |
| 3 | HTR7 | 5-hydroxytryptamine receptor 7 [Source:HGNC Symbol;Acc:HGNC:5302] | 4913 | 0.312 | -0.0170 | No |
| 4 | GRID1 | glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575] | 4973 | 0.291 | -0.0072 | No |
| 5 | GRIN2D | glutamate ionotropic receptor NMDA type subunit 2D [Source:HGNC Symbol;Acc:HGNC:4588] | 5297 | 0.185 | -0.0087 | No |
| 6 | GRIA1 | glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571] | 8935 | 0.000 | -0.1071 | No |
| 7 | GRIA2 | glutamate ionotropic receptor AMPA type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4572] | 8936 | 0.000 | -0.1071 | No |
| 8 | GRIA3 | glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573] | 8946 | 0.000 | -0.1073 | No |
| 9 | GRIA4 | glutamate ionotropic receptor AMPA type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4574] | 8948 | 0.000 | -0.1074 | No |
| 10 | GRID2 | glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576] | 8966 | 0.000 | -0.1078 | No |
| 11 | GRIK3 | glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581] | 9060 | 0.000 | -0.1103 | No |
| 12 | GRIK4 | glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582] | 9061 | 0.000 | -0.1103 | No |
| 13 | GRIK1 | glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579] | 9062 | 0.000 | -0.1103 | No |
| 14 | GRM1 | glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593] | 9685 | 0.000 | -0.1272 | No |
| 15 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 9689 | 0.000 | -0.1272 | No |
| 16 | GRIN2A | glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585] | 10060 | 0.000 | -0.1372 | No |
| 17 | GRIN2C | glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] | 10074 | 0.000 | -0.1376 | No |
| 18 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B [Source:HGNC Symbol;Acc:HGNC:4586] | 10075 | 0.000 | -0.1376 | No |
| 19 | GRIN3B | glutamate ionotropic receptor NMDA type subunit 3B [Source:HGNC Symbol;Acc:HGNC:16768] | 10077 | 0.000 | -0.1376 | No |
| 20 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] | 10078 | 0.000 | -0.1376 | No |
| 21 | GLRA1 | glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326] | 12758 | 0.000 | -0.2101 | No |
| 22 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12762 | 0.000 | -0.2101 | No |
| 23 | GLRA3 | glycine receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4328] | 12763 | 0.000 | -0.2101 | No |
| 24 | CHRFAM7A | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781] | 13031 | 0.000 | -0.2174 | No |
| 25 | OR6T1 | olfactory receptor family 6 subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:14848] | 14259 | 0.000 | -0.2505 | No |
| 26 | OR5T3 | olfactory receptor family 5 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:15297] | 14733 | 0.000 | -0.2633 | No |
| 27 | OR5T2 | olfactory receptor family 5 subfamily T member 2 [Source:HGNC Symbol;Acc:HGNC:15296] | 14735 | 0.000 | -0.2634 | No |
| 28 | HTR4 | 5-hydroxytryptamine receptor 4 [Source:HGNC Symbol;Acc:HGNC:5299] | 15424 | 0.000 | -0.2820 | No |
| 29 | HTR6 | 5-hydroxytryptamine receptor 6 [Source:HGNC Symbol;Acc:HGNC:5301] | 15426 | 0.000 | -0.2820 | No |
| 30 | HTR1E | 5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291] | 15490 | 0.000 | -0.2837 | No |
| 31 | HTR1F | 5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292] | 15492 | 0.000 | -0.2837 | No |
| 32 | HTR1D | 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] | 15493 | 0.000 | -0.2837 | No |
| 33 | HTR1A | 5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286] | 15494 | 0.000 | -0.2837 | No |
| 34 | HTR2B | 5-hydroxytryptamine receptor 2B [Source:HGNC Symbol;Acc:HGNC:5294] | 15501 | 0.000 | -0.2839 | No |
| 35 | HTR2C | 5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295] | 15502 | 0.000 | -0.2839 | No |
| 36 | HTR2A | 5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293] | 15503 | 0.000 | -0.2839 | No |
| 37 | HTR3E | 5-hydroxytryptamine receptor 3E [Source:HGNC Symbol;Acc:HGNC:24005] | 15507 | 0.000 | -0.2840 | No |
| 38 | HTR3C | 5-hydroxytryptamine receptor 3C [Source:HGNC Symbol;Acc:HGNC:24003] | 15508 | 0.000 | -0.2840 | No |
| 39 | HTR3D | 5-hydroxytryptamine receptor 3D [Source:HGNC Symbol;Acc:HGNC:24004] | 15509 | 0.000 | -0.2840 | No |
| 40 | HTR3A | 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] | 15510 | 0.000 | -0.2840 | No |
| 41 | HTR3B | 5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298] | 15511 | 0.000 | -0.2840 | No |
| 42 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15522 | 0.000 | -0.2842 | No |
| 43 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16708 | 0.000 | -0.3163 | No |
| 44 | GABRE | gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085] | 17269 | 0.000 | -0.3314 | No |
| 45 | GABRD | gamma-aminobutyric acid type A receptor subunit delta [Source:HGNC Symbol;Acc:HGNC:4084] | 17272 | 0.000 | -0.3315 | No |
| 46 | GABRQ | gamma-aminobutyric acid type A receptor subunit theta [Source:HGNC Symbol;Acc:HGNC:14454] | 17274 | 0.000 | -0.3315 | No |
| 47 | GABRP | gamma-aminobutyric acid type A receptor subunit pi [Source:HGNC Symbol;Acc:HGNC:4089] | 17275 | 0.000 | -0.3315 | No |
| 48 | CHRND | cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965] | 17800 | 0.000 | -0.3457 | No |
| 49 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17801 | 0.000 | -0.3457 | No |
| 50 | CHRNE | cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966] | 17802 | 0.000 | -0.3457 | No |
| 51 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17811 | 0.000 | -0.3459 | No |
| 52 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17813 | 0.000 | -0.3459 | No |
| 53 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17814 | 0.000 | -0.3459 | No |
| 54 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17815 | 0.000 | -0.3459 | No |
| 55 | ADRB1 | adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285] | 17925 | 0.000 | -0.3489 | No |
| 56 | DRD1 | dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020] | 18480 | 0.000 | -0.3639 | No |
| 57 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18481 | 0.000 | -0.3639 | No |
| 58 | DRD3 | dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024] | 18483 | 0.000 | -0.3639 | No |
| 59 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18484 | 0.000 | -0.3639 | No |
| 60 | DRD5 | dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] | 18485 | 0.000 | -0.3639 | No |
| 61 | CHRNA10 | cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800] | 19822 | 0.000 | -0.4000 | No |
| 62 | GABRG3 | gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088] | 19929 | 0.000 | -0.4029 | No |
| 63 | GABRG2 | gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087] | 19930 | 0.000 | -0.4029 | No |
| 64 | GABRG1 | gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086] | 19931 | 0.000 | -0.4029 | No |
| 65 | GABRB3 | gamma-aminobutyric acid type A receptor subunit beta3 [Source:HGNC Symbol;Acc:HGNC:4083] | 19977 | 0.000 | -0.4041 | No |
| 66 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19978 | 0.000 | -0.4041 | No |
| 67 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 19979 | 0.000 | -0.4041 | No |
| 68 | CHRNB3 | cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963] | 21703 | 0.000 | -0.4507 | No |
| 69 | CHRNA1 | cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955] | 21727 | 0.000 | -0.4513 | No |
| 70 | CHRNA3 | cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957] | 21731 | 0.000 | -0.4514 | No |
| 71 | CHRNA2 | cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956] | 21732 | 0.000 | -0.4514 | No |
| 72 | CHRNA5 | cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959] | 21733 | 0.000 | -0.4514 | No |
| 73 | CHRNA4 | cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958] | 21734 | 0.000 | -0.4514 | No |
| 74 | CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960] | 21736 | 0.000 | -0.4514 | No |
| 75 | CHRNA6 | cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963] | 21739 | 0.000 | -0.4515 | No |
| 76 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21742 | 0.000 | -0.4515 | No |
| 77 | ZACN | zinc activated ion channel [Source:HGNC Symbol;Acc:HGNC:29504] | 22551 | 0.000 | -0.4734 | No |
| 78 | OR10J5 | olfactory receptor family 10 subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:14993] | 22823 | 0.000 | -0.4807 | No |
| 79 | OR10H1 | olfactory receptor family 10 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:8172] | 22851 | 0.000 | -0.4814 | No |
| 80 | OR10H3 | olfactory receptor family 10 subfamily H member 3 [Source:HGNC Symbol;Acc:HGNC:8174] | 22852 | 0.000 | -0.4814 | No |
| 81 | OR10H2 | olfactory receptor family 10 subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:8173] | 22853 | 0.000 | -0.4814 | No |
| 82 | OR10H5 | olfactory receptor family 10 subfamily H member 5 [Source:HGNC Symbol;Acc:HGNC:15389] | 22854 | 0.000 | -0.4814 | No |
| 83 | OR10H4 | olfactory receptor family 10 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15388] | 22855 | 0.000 | -0.4814 | No |
| 84 | OR11H4 | olfactory receptor family 11 subfamily H member 4 [Source:HGNC Symbol;Acc:HGNC:15347] | 23090 | 0.000 | -0.4878 | No |
| 85 | OR11H7 | olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350] | 23099 | 0.000 | -0.4880 | No |
| 86 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 23903 | 0.000 | -0.5097 | No |
| 87 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 23906 | 0.000 | -0.5097 | No |
| 88 | HRH2 | histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183] | 23908 | 0.000 | -0.5098 | No |
| 89 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 23911 | 0.000 | -0.5098 | No |
| 90 | OR10J6P | olfactory receptor family 10 subfamily J member 6 pseudogene [Source:HGNC Symbol;Acc:HGNC:14994] | 24227 | 0.000 | -0.5183 | No |
| 91 | GABRA2 | gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076] | 24658 | 0.000 | -0.5300 | No |
| 92 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 24659 | 0.000 | -0.5300 | No |
| 93 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 24661 | 0.000 | -0.5300 | No |
| 94 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 24662 | 0.000 | -0.5300 | No |
| 95 | GABRA4 | gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] | 24663 | 0.000 | -0.5300 | No |
| 96 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077] | 24664 | 0.000 | -0.5300 | No |
| 97 | GABRR3 | gamma-aminobutyric acid type A receptor subunit rho3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:17969] | 24802 | 0.000 | -0.5337 | No |
| 98 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 24803 | 0.000 | -0.5337 | No |
| 99 | GABRR1 | gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090] | 24805 | 0.000 | -0.5337 | No |
| 100 | P2RY11 | purinergic receptor P2Y11 [Source:HGNC Symbol;Acc:HGNC:8540] | 26167 | 0.000 | -0.5705 | No |
| 101 | GLRB | glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329] | 26722 | 0.000 | -0.5855 | No |
| 102 | GABBR1 | gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070] | 27139 | 0.000 | -0.5968 | No |
| 103 | CHRNB4 | cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964] | 28384 | -0.079 | -0.6273 | No |
| 104 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 28819 | -0.188 | -0.6317 | No |
| 105 | CHRNB2 | cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962] | 33350 | -1.594 | -0.6922 | Yes |
| 106 | CHRNB1 | cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961] | 34135 | -1.986 | -0.6360 | Yes |
| 107 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 34396 | -2.127 | -0.5602 | Yes |
| 108 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 35744 | -3.082 | -0.4766 | Yes |
| 109 | ANXA9 | annexin A9 [Source:HGNC Symbol;Acc:HGNC:547] | 36597 | -4.010 | -0.3435 | Yes |
| 110 | GRIN1 | glutamate ionotropic receptor NMDA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4584] | 36925 | -4.497 | -0.1771 | Yes |
| 111 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 36990 | -4.662 | 0.0027 | Yes |
