Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.85727316 |
| Normalized Enrichment Score (NES) | -1.7125738 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0025377397 |
| FWER p-Value | 0.011 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GRID1 | glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575] | 4973 | 0.291 | -0.1125 | No |
| 2 | GRIA1 | glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571] | 8935 | 0.000 | -0.2195 | No |
| 3 | GRIA3 | glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573] | 8946 | 0.000 | -0.2197 | No |
| 4 | GRID2 | glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576] | 8966 | 0.000 | -0.2202 | No |
| 5 | GRIK3 | glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581] | 9060 | 0.000 | -0.2227 | No |
| 6 | GRIK4 | glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582] | 9061 | 0.000 | -0.2227 | No |
| 7 | GRIK1 | glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579] | 9062 | 0.000 | -0.2227 | No |
| 8 | GRM1 | glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593] | 9685 | 0.000 | -0.2395 | No |
| 9 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 9689 | 0.000 | -0.2396 | No |
| 10 | GRIN2C | glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] | 10074 | 0.000 | -0.2500 | No |
| 11 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] | 10078 | 0.000 | -0.2501 | No |
| 12 | GLRA1 | glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326] | 12758 | 0.000 | -0.3224 | No |
| 13 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12762 | 0.000 | -0.3225 | No |
| 14 | CHRFAM7A | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781] | 13031 | 0.000 | -0.3297 | No |
| 15 | GABRE | gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085] | 17269 | 0.000 | -0.4442 | No |
| 16 | CHRND | cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965] | 17800 | 0.000 | -0.4585 | No |
| 17 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17801 | 0.000 | -0.4585 | No |
| 18 | CHRNE | cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966] | 17802 | 0.000 | -0.4585 | No |
| 19 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17811 | 0.000 | -0.4587 | No |
| 20 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 17813 | 0.000 | -0.4587 | No |
| 21 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17814 | 0.000 | -0.4587 | No |
| 22 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17815 | 0.000 | -0.4587 | No |
| 23 | ADRB1 | adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285] | 17925 | 0.000 | -0.4617 | No |
| 24 | DRD1 | dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020] | 18480 | 0.000 | -0.4766 | No |
| 25 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18481 | 0.000 | -0.4766 | No |
| 26 | DRD3 | dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024] | 18483 | 0.000 | -0.4767 | No |
| 27 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18484 | 0.000 | -0.4767 | No |
| 28 | DRD5 | dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] | 18485 | 0.000 | -0.4767 | No |
| 29 | CHRNA10 | cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800] | 19822 | 0.000 | -0.5127 | No |
| 30 | GABRG3 | gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088] | 19929 | 0.000 | -0.5156 | No |
| 31 | GABRG2 | gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087] | 19930 | 0.000 | -0.5156 | No |
| 32 | GABRG1 | gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086] | 19931 | 0.000 | -0.5156 | No |
| 33 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19978 | 0.000 | -0.5168 | No |
| 34 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 19979 | 0.000 | -0.5168 | No |
| 35 | CHRNB3 | cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963] | 21703 | 0.000 | -0.5634 | No |
| 36 | CHRNA1 | cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955] | 21727 | 0.000 | -0.5640 | No |
| 37 | CHRNA3 | cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957] | 21731 | 0.000 | -0.5641 | No |
| 38 | CHRNA2 | cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956] | 21732 | 0.000 | -0.5641 | No |
| 39 | CHRNA5 | cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959] | 21733 | 0.000 | -0.5641 | No |
| 40 | CHRNA4 | cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958] | 21734 | 0.000 | -0.5641 | No |
| 41 | CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960] | 21736 | 0.000 | -0.5641 | No |
| 42 | CHRNA6 | cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963] | 21739 | 0.000 | -0.5642 | No |
| 43 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21742 | 0.000 | -0.5642 | No |
| 44 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 23906 | 0.000 | -0.6226 | No |
| 45 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 23911 | 0.000 | -0.6227 | No |
| 46 | GABRA2 | gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076] | 24658 | 0.000 | -0.6429 | No |
| 47 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 24659 | 0.000 | -0.6429 | No |
| 48 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 24661 | 0.000 | -0.6429 | No |
| 49 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 24662 | 0.000 | -0.6429 | No |
| 50 | GABRA4 | gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] | 24663 | 0.000 | -0.6429 | No |
| 51 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077] | 24664 | 0.000 | -0.6429 | No |
| 52 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 24803 | 0.000 | -0.6466 | No |
| 53 | GABRR1 | gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090] | 24805 | 0.000 | -0.6467 | No |
| 54 | GLRB | glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329] | 26722 | 0.000 | -0.6984 | No |
| 55 | GABBR1 | gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070] | 27139 | 0.000 | -0.7096 | No |
| 56 | CHRNB4 | cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964] | 28384 | -0.079 | -0.7373 | No |
| 57 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 28819 | -0.188 | -0.7349 | No |
| 58 | CHRNB2 | cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962] | 33350 | -1.594 | -0.7380 | Yes |
| 59 | CHRNB1 | cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961] | 34135 | -1.986 | -0.6105 | Yes |
| 60 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 34396 | -2.127 | -0.4582 | Yes |
| 61 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 35744 | -3.082 | -0.2639 | Yes |
| 62 | ANXA9 | annexin A9 [Source:HGNC Symbol;Acc:HGNC:547] | 36597 | -4.010 | 0.0133 | Yes |
