Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CAHOY_OLIGODENDROCUTIC |
| Enrichment Score (ES) | -0.6501596 |
| Normalized Enrichment Score (NES) | -1.340654 |
| Nominal p-value | 0.023041476 |
| FDR q-value | 0.15660848 |
| FWER p-Value | 0.875 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 346 | 3.620 | 0.0182 | No |
| 2 | ADGRL2 | adhesion G protein-coupled receptor L2 [Source:HGNC Symbol;Acc:HGNC:18582] | 649 | 2.868 | 0.0318 | No |
| 3 | DOCK10 | dedicator of cytokinesis 10 [Source:HGNC Symbol;Acc:HGNC:23479] | 785 | 2.677 | 0.0485 | No |
| 4 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 1146 | 2.099 | 0.0547 | No |
| 5 | HIP1R | huntingtin interacting protein 1 related [Source:HGNC Symbol;Acc:HGNC:18415] | 1326 | 1.998 | 0.0651 | No |
| 6 | EFHD2 | EF-hand domain family member D2 [Source:HGNC Symbol;Acc:HGNC:28670] | 1332 | 1.994 | 0.0801 | No |
| 7 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 1840 | 1.519 | 0.0779 | No |
| 8 | RBM11 | RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897] | 1870 | 1.492 | 0.0885 | No |
| 9 | USP16 | ubiquitin specific peptidase 16 [Source:HGNC Symbol;Acc:HGNC:12614] | 3147 | 0.818 | 0.0602 | No |
| 10 | ZNF276 | zinc finger protein 276 [Source:HGNC Symbol;Acc:HGNC:23330] | 3209 | 0.791 | 0.0646 | No |
| 11 | NGRN | neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077] | 3500 | 0.683 | 0.0619 | No |
| 12 | COL20A1 | collagen type XX alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:14670] | 4397 | 0.473 | 0.0413 | No |
| 13 | PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9581] | 4504 | 0.442 | 0.0418 | No |
| 14 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 4603 | 0.405 | 0.0422 | No |
| 15 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 4793 | 0.350 | 0.0398 | No |
| 16 | CPOX | coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321] | 5239 | 0.205 | 0.0293 | No |
| 17 | WIPF1 | WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736] | 5645 | 0.095 | 0.0190 | No |
| 18 | NCMAP | non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332] | 6547 | 0.000 | -0.0053 | No |
| 19 | PRKCQ | protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] | 6599 | 0.000 | -0.0067 | No |
| 20 | GAL3ST1 | galactose-3-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:24240] | 6695 | 0.000 | -0.0093 | No |
| 21 | CNTNAP2 | contactin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:13830] | 7055 | 0.000 | -0.0190 | No |
| 22 | FA2H | fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] | 7308 | 0.000 | -0.0258 | No |
| 23 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 7939 | 0.000 | -0.0428 | No |
| 24 | MAP6D1 | MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753] | 8131 | 0.000 | -0.0480 | No |
| 25 | SOX10 | SRY-box transcription factor 10 [Source:HGNC Symbol;Acc:HGNC:11190] | 8518 | 0.000 | -0.0584 | No |
| 26 | NINJ2 | ninjurin 2 [Source:HGNC Symbol;Acc:HGNC:7825] | 9579 | 0.000 | -0.0871 | No |
| 27 | PLLP | plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553] | 9782 | 0.000 | -0.0925 | No |
| 28 | TSPAN2 | tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659] | 11302 | 0.000 | -0.1336 | No |
| 29 | BACE1 | beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933] | 11508 | 0.000 | -0.1391 | No |
| 30 | ATP10B | ATPase phospholipid transporting 10B (putative) [Source:HGNC Symbol;Acc:HGNC:13543] | 11965 | 0.000 | -0.1515 | No |
| 31 | TENM1 | teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117] | 12567 | 0.000 | -0.1677 | No |
| 32 | CDR2L | cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999] | 12896 | 0.000 | -0.1766 | No |
| 33 | DMRTA1 | DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826] | 14829 | 0.000 | -0.2288 | No |
| 34 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15941 | 0.000 | -0.2588 | No |
| 35 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16288 | 0.000 | -0.2682 | No |
| 36 | GPR17 | G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471] | 17440 | 0.000 | -0.2993 | No |
| 37 | SEMA3D | semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726] | 17848 | 0.000 | -0.3103 | No |
| 38 | BFSP2 | beaded filament structural protein 2 [Source:HGNC Symbol;Acc:HGNC:1041] | 18198 | 0.000 | -0.3197 | No |
| 39 | FEZF2 | FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506] | 18652 | 0.000 | -0.3320 | No |
| 40 | AGAP11 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 [Source:HGNC Symbol;Acc:HGNC:29421] | 19698 | 0.000 | -0.3602 | No |
| 41 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 21359 | 0.000 | -0.4051 | No |
| 42 | UGT8 | UDP glycosyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:12555] | 21841 | 0.000 | -0.4181 | No |
| 43 | CSDC2 | cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359] | 22979 | 0.000 | -0.4488 | No |
| 44 | FIGN | fidgetin, microtubule severing factor [Source:HGNC Symbol;Acc:HGNC:13285] | 23154 | 0.000 | -0.4536 | No |
| 45 | SOX8 | SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203] | 23229 | 0.000 | -0.4556 | No |
| 46 | DUSP15 | dual specificity phosphatase 15 [Source:HGNC Symbol;Acc:HGNC:16236] | 25325 | 0.000 | -0.5122 | No |
| 47 | GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488] | 25444 | 0.000 | -0.5154 | No |
| 48 | GJE1 | gap junction protein epsilon 1 [Source:HGNC Symbol;Acc:HGNC:33251] | 25720 | 0.000 | -0.5228 | No |
| 49 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 26154 | 0.000 | -0.5345 | No |
| 50 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 26665 | 0.000 | -0.5483 | No |
| 51 | GNG8 | G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664] | 27235 | 0.000 | -0.5637 | No |
| 52 | FAM89A | family with sequence similarity 89 member A [Source:HGNC Symbol;Acc:HGNC:25057] | 27515 | 0.000 | -0.5712 | No |
| 53 | LHFPL6 | LHFPL tetraspan subfamily member 6 [Source:HGNC Symbol;Acc:HGNC:6586] | 27578 | 0.000 | -0.5729 | No |
| 54 | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 28276 | -0.047 | -0.5914 | No |
| 55 | POP4 | POP4 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:30081] | 30090 | -0.523 | -0.6364 | No |
| 56 | SIRT2 | sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886] | 30599 | -0.650 | -0.6452 | Yes |
| 57 | NR2C1 | nuclear receptor subfamily 2 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7971] | 30680 | -0.680 | -0.6422 | Yes |
| 58 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 30795 | -0.709 | -0.6399 | Yes |
| 59 | BCAS1 | brain enriched myelin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:974] | 30803 | -0.711 | -0.6347 | Yes |
| 60 | DUSP19 | dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894] | 30859 | -0.730 | -0.6306 | Yes |
| 61 | RNASEH2B | ribonuclease H2 subunit B [Source:HGNC Symbol;Acc:HGNC:25671] | 31348 | -0.875 | -0.6372 | Yes |
| 62 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 31425 | -0.903 | -0.6324 | Yes |
| 63 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 31636 | -0.969 | -0.6307 | Yes |
| 64 | FBXO7 | F-box protein 7 [Source:HGNC Symbol;Acc:HGNC:13586] | 31670 | -0.982 | -0.6241 | Yes |
| 65 | SPEG | striated muscle enriched protein kinase [Source:HGNC Symbol;Acc:HGNC:16901] | 31870 | -1.047 | -0.6215 | Yes |
| 66 | RNF122 | ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147] | 32006 | -1.096 | -0.6169 | Yes |
| 67 | TLCD3A | TLC domain containing 3A [Source:HGNC Symbol;Acc:HGNC:29646] | 32469 | -1.232 | -0.6200 | Yes |
| 68 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 33087 | -1.487 | -0.6254 | Yes |
| 69 | PPP1R21 | protein phosphatase 1 regulatory subunit 21 [Source:HGNC Symbol;Acc:HGNC:30595] | 33223 | -1.543 | -0.6173 | Yes |
| 70 | PKIG | cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019] | 33312 | -1.582 | -0.6076 | Yes |
| 71 | AP5Z1 | adaptor related protein complex 5 subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:22197] | 33679 | -1.740 | -0.6043 | Yes |
| 72 | DCPS | decapping enzyme, scavenger [Source:HGNC Symbol;Acc:HGNC:29812] | 33895 | -1.866 | -0.5959 | Yes |
| 73 | SRPK3 | SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402] | 33984 | -1.903 | -0.5839 | Yes |
| 74 | EPN2 | epsin 2 [Source:HGNC Symbol;Acc:HGNC:18639] | 34226 | -2.038 | -0.5749 | Yes |
| 75 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 34455 | -2.128 | -0.5649 | Yes |
| 76 | IFFO1 | intermediate filament family orphan 1 [Source:HGNC Symbol;Acc:HGNC:24970] | 34558 | -2.203 | -0.5509 | Yes |
| 77 | KIAA1958 | KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427] | 34561 | -2.205 | -0.5342 | Yes |
| 78 | PUS7 | pseudouridine synthase 7 [Source:HGNC Symbol;Acc:HGNC:26033] | 34748 | -2.315 | -0.5216 | Yes |
| 79 | SERINC5 | serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825] | 35208 | -2.657 | -0.5138 | Yes |
| 80 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 35418 | -2.769 | -0.4985 | Yes |
| 81 | RTKN | rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] | 35472 | -2.811 | -0.4785 | Yes |
| 82 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 35599 | -2.946 | -0.4595 | Yes |
| 83 | CLYBL | citramalyl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:18355] | 35609 | -2.959 | -0.4373 | Yes |
| 84 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35624 | -2.974 | -0.4151 | Yes |
| 85 | KCTD1 | potassium channel tetramerization domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18249] | 35742 | -3.080 | -0.3948 | Yes |
| 86 | MAP3K15 | mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689] | 35852 | -3.189 | -0.3735 | Yes |
| 87 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 35866 | -3.204 | -0.3495 | Yes |
| 88 | ABHD8 | abhydrolase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:23759] | 35972 | -3.323 | -0.3271 | Yes |
| 89 | CILK1 | ciliogenesis associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:21219] | 36087 | -3.422 | -0.3042 | Yes |
| 90 | RCBTB1 | RCC1 and BTB domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:18243] | 36089 | -3.429 | -0.2782 | Yes |
| 91 | LCORL | ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776] | 36136 | -3.469 | -0.2530 | Yes |
| 92 | PRKAG2 | protein kinase AMP-activated non-catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:9386] | 36171 | -3.498 | -0.2274 | Yes |
| 93 | BCR | BCR activator of RhoGEF and GTPase [Source:HGNC Symbol;Acc:HGNC:1014] | 36190 | -3.523 | -0.2011 | Yes |
| 94 | ELOVL6 | ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] | 36294 | -3.619 | -0.1764 | Yes |
| 95 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 36466 | -3.829 | -0.1519 | Yes |
| 96 | DOCK7 | dedicator of cytokinesis 7 [Source:HGNC Symbol;Acc:HGNC:19190] | 36666 | -4.077 | -0.1263 | Yes |
| 97 | P4HA2 | prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547] | 36856 | -4.385 | -0.0981 | Yes |
| 98 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36884 | -4.436 | -0.0651 | Yes |
| 99 | LRRC75A | leucine rich repeat containing 75A [Source:HGNC Symbol;Acc:HGNC:32403] | 36898 | -4.459 | -0.0316 | Yes |
| 100 | PLXNB3 | plexin B3 [Source:HGNC Symbol;Acc:HGNC:9105] | 37037 | -4.831 | 0.0014 | Yes |
