Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.46420896 |
| Normalized Enrichment Score (NES) | 1.2189404 |
| Nominal p-value | 0.038961038 |
| FDR q-value | 0.1697076 |
| FWER p-Value | 0.572 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 17 | 4.971 | 0.0432 | Yes |
| 2 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 36 | 4.926 | 0.0859 | Yes |
| 3 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 55 | 4.827 | 0.1278 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 66 | 4.776 | 0.1694 | Yes |
| 5 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.2106 | Yes |
| 6 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 307 | 3.781 | 0.2376 | Yes |
| 7 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 341 | 3.647 | 0.2687 | Yes |
| 8 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 536 | 3.138 | 0.2910 | Yes |
| 9 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 538 | 3.138 | 0.3185 | Yes |
| 10 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 600 | 2.986 | 0.3430 | Yes |
| 11 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 714 | 2.837 | 0.3649 | Yes |
| 12 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 764 | 2.708 | 0.3873 | Yes |
| 13 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 806 | 2.638 | 0.4093 | Yes |
| 14 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 870 | 2.517 | 0.4297 | Yes |
| 15 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 950 | 2.400 | 0.4486 | Yes |
| 16 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 1083 | 2.182 | 0.4642 | Yes |
| 17 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 1912 | 1.458 | 0.4546 | No |
| 18 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 3077 | 0.849 | 0.4305 | No |
| 19 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 3161 | 0.810 | 0.4354 | No |
| 20 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 3511 | 0.679 | 0.4319 | No |
| 21 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 3823 | 0.554 | 0.4284 | No |
| 22 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 3829 | 0.553 | 0.4331 | No |
| 23 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 3965 | 0.500 | 0.4338 | No |
| 24 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 4001 | 0.488 | 0.4372 | No |
| 25 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 4394 | 0.473 | 0.4307 | No |
| 26 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 5153 | 0.230 | 0.4122 | No |
| 27 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 5339 | 0.177 | 0.4088 | No |
| 28 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 5362 | 0.170 | 0.4096 | No |
| 29 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 5587 | 0.113 | 0.4046 | No |
| 30 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6032 | 0.000 | 0.3926 | No |
| 31 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6050 | 0.000 | 0.3921 | No |
| 32 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 6577 | 0.000 | 0.3779 | No |
| 33 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7116 | 0.000 | 0.3633 | No |
| 34 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 7450 | 0.000 | 0.3543 | No |
| 35 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 7554 | 0.000 | 0.3515 | No |
| 36 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 7774 | 0.000 | 0.3456 | No |
| 37 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 8030 | 0.000 | 0.3387 | No |
| 38 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8080 | 0.000 | 0.3374 | No |
| 39 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 9209 | 0.000 | 0.3068 | No |
| 40 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9292 | 0.000 | 0.3046 | No |
| 41 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 9512 | 0.000 | 0.2987 | No |
| 42 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 9587 | 0.000 | 0.2967 | No |
| 43 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 9687 | 0.000 | 0.2940 | No |
| 44 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 9690 | 0.000 | 0.2940 | No |
| 45 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9693 | 0.000 | 0.2939 | No |
| 46 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10110 | 0.000 | 0.2826 | No |
| 47 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 10804 | 0.000 | 0.2639 | No |
| 48 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11168 | 0.000 | 0.2541 | No |
| 49 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11280 | 0.000 | 0.2511 | No |
| 50 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11288 | 0.000 | 0.2509 | No |
| 51 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11307 | 0.000 | 0.2504 | No |
| 52 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 11624 | 0.000 | 0.2418 | No |
| 53 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 11648 | 0.000 | 0.2412 | No |
| 54 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 11674 | 0.000 | 0.2405 | No |
| 55 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 12087 | 0.000 | 0.2294 | No |
| 56 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12445 | 0.000 | 0.2197 | No |
| 57 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 12508 | 0.000 | 0.2181 | No |
| 58 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12569 | 0.000 | 0.2164 | No |
| 59 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13274 | 0.000 | 0.1974 | No |
| 60 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13282 | 0.000 | 0.1972 | No |
| 61 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13377 | 0.000 | 0.1946 | No |
| 62 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13619 | 0.000 | 0.1881 | No |
| 63 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 13703 | 0.000 | 0.1859 | No |
| 64 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14035 | 0.000 | 0.1769 | No |
| 65 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14373 | 0.000 | 0.1678 | No |
| 66 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 15803 | 0.000 | 0.1291 | No |
| 67 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 15907 | 0.000 | 0.1264 | No |
| 68 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 15935 | 0.000 | 0.1256 | No |
| 69 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 16080 | 0.000 | 0.1217 | No |
| 70 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16102 | 0.000 | 0.1212 | No |
| 71 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16198 | 0.000 | 0.1186 | No |
| 72 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17448 | 0.000 | 0.0848 | No |
| 73 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17522 | 0.000 | 0.0828 | No |
| 74 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17801 | 0.000 | 0.0753 | No |
| 75 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17811 | 0.000 | 0.0750 | No |
| 76 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18180 | 0.000 | 0.0651 | No |
| 77 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18186 | 0.000 | 0.0650 | No |
| 78 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18934 | 0.000 | 0.0447 | No |
| 79 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 18953 | 0.000 | 0.0443 | No |
| 80 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19075 | 0.000 | 0.0410 | No |
| 81 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19098 | 0.000 | 0.0404 | No |
| 82 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 19166 | 0.000 | 0.0386 | No |
| 83 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19309 | 0.000 | 0.0347 | No |
| 84 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19820 | 0.000 | 0.0209 | No |
| 85 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 19867 | 0.000 | 0.0197 | No |
| 86 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 20002 | 0.000 | 0.0161 | No |
| 87 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 20228 | 0.000 | 0.0100 | No |
| 88 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 20575 | 0.000 | 0.0006 | No |
| 89 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 20579 | 0.000 | 0.0005 | No |
| 90 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 20737 | 0.000 | -0.0037 | No |
| 91 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 20752 | 0.000 | -0.0041 | No |
| 92 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 21152 | 0.000 | -0.0149 | No |
| 93 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 21671 | 0.000 | -0.0289 | No |
| 94 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21742 | 0.000 | -0.0308 | No |
| 95 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 22233 | 0.000 | -0.0441 | No |
| 96 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 22785 | 0.000 | -0.0590 | No |
| 97 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 22992 | 0.000 | -0.0646 | No |
| 98 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 23470 | 0.000 | -0.0775 | No |
| 99 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 23629 | 0.000 | -0.0817 | No |
| 100 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 23635 | 0.000 | -0.0819 | No |
| 101 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 24059 | 0.000 | -0.0933 | No |
| 102 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 24072 | 0.000 | -0.0936 | No |
| 103 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 24249 | 0.000 | -0.0984 | No |
| 104 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 24272 | 0.000 | -0.0990 | No |
| 105 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 24794 | 0.000 | -0.1131 | No |
| 106 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 25184 | 0.000 | -0.1236 | No |
| 107 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 25384 | 0.000 | -0.1290 | No |
| 108 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 25912 | 0.000 | -0.1433 | No |
| 109 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 26684 | 0.000 | -0.1641 | No |
| 110 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 26685 | 0.000 | -0.1641 | No |
| 111 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 26829 | 0.000 | -0.1680 | No |
| 112 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 27788 | 0.000 | -0.1939 | No |
| 113 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 29546 | -0.373 | -0.2382 | No |
| 114 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 30185 | -0.537 | -0.2507 | No |
| 115 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 31995 | -1.091 | -0.2901 | No |
| 116 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 32026 | -1.104 | -0.2813 | No |
| 117 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 32035 | -1.107 | -0.2718 | No |
| 118 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 32090 | -1.132 | -0.2633 | No |
| 119 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 32103 | -1.138 | -0.2536 | No |
| 120 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 32113 | -1.141 | -0.2439 | No |
| 121 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 33216 | -1.541 | -0.2601 | No |
| 122 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 33486 | -1.660 | -0.2529 | No |
| 123 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 33921 | -1.879 | -0.2481 | No |
| 124 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 34572 | -2.215 | -0.2463 | No |
| 125 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 34957 | -2.450 | -0.2352 | No |
| 126 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 35191 | -2.638 | -0.2183 | No |
| 127 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 35418 | -2.769 | -0.2001 | No |
| 128 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 35606 | -2.956 | -0.1793 | No |
| 129 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 35724 | -3.061 | -0.1556 | No |
| 130 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 35866 | -3.204 | -0.1313 | No |
| 131 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 36098 | -3.435 | -0.1074 | No |
| 132 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 36296 | -3.622 | -0.0809 | No |
| 133 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36468 | -3.830 | -0.0520 | No |
| 134 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 36520 | -3.908 | -0.0191 | No |
| 135 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 36543 | -3.926 | 0.0148 | No |
