Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KRAS.KIDNEY_UP.V1_UP |
| Enrichment Score (ES) | -0.6396244 |
| Normalized Enrichment Score (NES) | -1.3584741 |
| Nominal p-value | 0.0076670316 |
| FDR q-value | 0.13885288 |
| FWER p-Value | 0.787 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 393 | 3.496 | 0.0350 | No |
| 2 | PLCL1 | phospholipase C like 1 (inactive) [Source:HGNC Symbol;Acc:HGNC:9063] | 1528 | 1.791 | 0.0277 | No |
| 3 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 1584 | 1.730 | 0.0488 | No |
| 4 | DDX6 | DEAD-box helicase 6 [Source:HGNC Symbol;Acc:HGNC:2747] | 1875 | 1.488 | 0.0603 | No |
| 5 | RNLS | renalase, FAD dependent amine oxidase [Source:HGNC Symbol;Acc:HGNC:25641] | 2130 | 1.340 | 0.0709 | No |
| 6 | SERPINI1 | serpin family I member 1 [Source:HGNC Symbol;Acc:HGNC:8943] | 2411 | 1.183 | 0.0788 | No |
| 7 | NME5 | NME/NM23 family member 5 [Source:HGNC Symbol;Acc:HGNC:7853] | 3192 | 0.797 | 0.0681 | No |
| 8 | SLC12A5 | solute carrier family 12 member 5 [Source:HGNC Symbol;Acc:HGNC:13818] | 3389 | 0.724 | 0.0723 | No |
| 9 | CPEB3 | cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:21746] | 3912 | 0.517 | 0.0649 | No |
| 10 | NUDT11 | nudix hydrolase 11 [Source:HGNC Symbol;Acc:HGNC:18011] | 4387 | 0.473 | 0.0582 | No |
| 11 | CAB39L | calcium binding protein 39 like [Source:HGNC Symbol;Acc:HGNC:20290] | 4530 | 0.430 | 0.0600 | No |
| 12 | KIT | KIT proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6342] | 5316 | 0.182 | 0.0411 | No |
| 13 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6180 | 0.000 | 0.0178 | No |
| 14 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6182 | 0.000 | 0.0177 | No |
| 15 | WSCD1 | WSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29060] | 6200 | 0.000 | 0.0173 | No |
| 16 | CRYAB | crystallin alpha B [Source:HGNC Symbol;Acc:HGNC:2389] | 6317 | 0.000 | 0.0141 | No |
| 17 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626] | 6320 | 0.000 | 0.0141 | No |
| 18 | DYNC1I1 | dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963] | 6539 | 0.000 | 0.0082 | No |
| 19 | AQP4 | aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637] | 6729 | 0.000 | 0.0031 | No |
| 20 | NRXN1 | neurexin 1 [Source:HGNC Symbol;Acc:HGNC:8008] | 6861 | 0.000 | -0.0005 | No |
| 21 | HPCAL4 | hippocalcin like 4 [Source:HGNC Symbol;Acc:HGNC:18212] | 6913 | 0.000 | -0.0019 | No |
| 22 | HEY1 | hes related family bHLH transcription factor with YRPW motif 1 [Source:HGNC Symbol;Acc:HGNC:4880] | 6971 | 0.000 | -0.0034 | No |
| 23 | GPRC5B | G protein-coupled receptor class C group 5 member B [Source:HGNC Symbol;Acc:HGNC:13308] | 6981 | 0.000 | -0.0036 | No |
| 24 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7462 | 0.000 | -0.0166 | No |
| 25 | MPZL2 | myelin protein zero like 2 [Source:HGNC Symbol;Acc:HGNC:3496] | 7571 | 0.000 | -0.0195 | No |
| 26 | EPB41L3 | erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380] | 7697 | 0.000 | -0.0229 | No |
| 27 | PCDH9 | protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661] | 7796 | 0.000 | -0.0256 | No |
| 28 | PELI2 | pellino E3 ubiquitin protein ligase family member 2 [Source:HGNC Symbol;Acc:HGNC:8828] | 8213 | 0.000 | -0.0368 | No |
| 29 | CALB1 | calbindin 1 [Source:HGNC Symbol;Acc:HGNC:1434] | 8477 | 0.000 | -0.0440 | No |
| 30 | SMR3A | submaxillary gland androgen regulated protein 3A [Source:HGNC Symbol;Acc:HGNC:19216] | 8598 | 0.000 | -0.0472 | No |
| 31 | PLSCR4 | phospholipid scramblase 4 [Source:HGNC Symbol;Acc:HGNC:16497] | 8907 | 0.000 | -0.0555 | No |
| 32 | GRIA2 | glutamate ionotropic receptor AMPA type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4572] | 8936 | 0.000 | -0.0563 | No |
| 33 | CDR1 | cerebellar degeneration related protein 1 [Source:HGNC Symbol;Acc:HGNC:1798] | 9232 | 0.000 | -0.0643 | No |
| 34 | NEBL | nebulette [Source:HGNC Symbol;Acc:HGNC:16932] | 9380 | 0.000 | -0.0683 | No |
| 35 | NEFL | neurofilament light [Source:HGNC Symbol;Acc:HGNC:7739] | 9397 | 0.000 | -0.0687 | No |
| 36 | KCNA5 | potassium voltage-gated channel subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:6224] | 9431 | 0.000 | -0.0696 | No |
| 37 | KCNJ8 | potassium inwardly rectifying channel subfamily J member 8 [Source:HGNC Symbol;Acc:HGNC:6269] | 9556 | 0.000 | -0.0729 | No |
| 38 | LIMCH1 | LIM and calponin homology domains 1 [Source:HGNC Symbol;Acc:HGNC:29191] | 9575 | 0.000 | -0.0734 | No |
| 39 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 9689 | 0.000 | -0.0765 | No |
| 40 | PMP2 | peripheral myelin protein 2 [Source:HGNC Symbol;Acc:HGNC:9117] | 10096 | 0.000 | -0.0875 | No |
| 41 | RTN1 | reticulon 1 [Source:HGNC Symbol;Acc:HGNC:10467] | 10236 | 0.000 | -0.0912 | No |
| 42 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10287 | 0.000 | -0.0926 | No |
| 43 | CHGB | chromogranin B [Source:HGNC Symbol;Acc:HGNC:1930] | 10308 | 0.000 | -0.0931 | No |
| 44 | SPARCL1 | SPARC like 1 [Source:HGNC Symbol;Acc:HGNC:11220] | 11114 | 0.000 | -0.1149 | No |
| 45 | ERC2 | ELKS/RAB6-interacting/CAST family member 2 [Source:HGNC Symbol;Acc:HGNC:31922] | 11240 | 0.000 | -0.1183 | No |
| 46 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 11626 | 0.000 | -0.1287 | No |
| 47 | SIGLEC15 | sialic acid binding Ig like lectin 15 [Source:HGNC Symbol;Acc:HGNC:27596] | 11659 | 0.000 | -0.1296 | No |
| 48 | NAP1L2 | nucleosome assembly protein 1 like 2 [Source:HGNC Symbol;Acc:HGNC:7638] | 11814 | 0.000 | -0.1337 | No |
| 49 | ITGBL1 | integrin subunit beta like 1 [Source:HGNC Symbol;Acc:HGNC:6164] | 12284 | 0.000 | -0.1464 | No |
| 50 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 12323 | 0.000 | -0.1475 | No |
| 51 | GAP43 | growth associated protein 43 [Source:HGNC Symbol;Acc:HGNC:4140] | 12636 | 0.000 | -0.1559 | No |
| 52 | GCGR | glucagon receptor [Source:HGNC Symbol;Acc:HGNC:4192] | 12957 | 0.000 | -0.1646 | No |
| 53 | ESRRG | estrogen related receptor gamma [Source:HGNC Symbol;Acc:HGNC:3474] | 13123 | 0.000 | -0.1690 | No |
| 54 | VIPR2 | vasoactive intestinal peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:12695] | 13213 | 0.000 | -0.1714 | No |
| 55 | RELN | reelin [Source:HGNC Symbol;Acc:HGNC:9957] | 13668 | 0.000 | -0.1837 | No |
| 56 | GHRH | growth hormone releasing hormone [Source:HGNC Symbol;Acc:HGNC:4265] | 15028 | 0.000 | -0.2205 | No |
| 57 | RIT2 | Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HGNC:10017] | 15320 | 0.000 | -0.2284 | No |
| 58 | PCP4 | Purkinje cell protein 4 [Source:HGNC Symbol;Acc:HGNC:8742] | 15345 | 0.000 | -0.2290 | No |
| 59 | SV2B | synaptic vesicle glycoprotein 2B [Source:HGNC Symbol;Acc:HGNC:16874] | 15641 | 0.000 | -0.2370 | No |
| 60 | TCEAL2 | transcription elongation factor A like 2 [Source:HGNC Symbol;Acc:HGNC:29818] | 15877 | 0.000 | -0.2434 | No |
| 61 | XK | X-linked Kx blood group [Source:HGNC Symbol;Acc:HGNC:12811] | 16212 | 0.000 | -0.2524 | No |
| 62 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16789] | 16391 | 0.000 | -0.2572 | No |
| 63 | GPM6A | glycoprotein M6A [Source:HGNC Symbol;Acc:HGNC:4460] | 16513 | 0.000 | -0.2605 | No |
| 64 | TRIB2 | tribbles pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:30809] | 16794 | 0.000 | -0.2681 | No |
| 65 | SYT1 | synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509] | 16957 | 0.000 | -0.2725 | No |
| 66 | GPR37 | G protein-coupled receptor 37 [Source:HGNC Symbol;Acc:HGNC:4494] | 17464 | 0.000 | -0.2862 | No |
| 67 | SLC12A3 | solute carrier family 12 member 3 [Source:HGNC Symbol;Acc:HGNC:10912] | 17544 | 0.000 | -0.2883 | No |
| 68 | TRIM9 | tripartite motif containing 9 [Source:HGNC Symbol;Acc:HGNC:16288] | 17779 | 0.000 | -0.2946 | No |
| 69 | FZD3 | frizzled class receptor 3 [Source:HGNC Symbol;Acc:HGNC:4041] | 19232 | 0.000 | -0.3339 | No |
| 70 | NDN | necdin, MAGE family member [Source:HGNC Symbol;Acc:HGNC:7675] | 19291 | 0.000 | -0.3355 | No |
| 71 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 19979 | 0.000 | -0.3541 | No |
| 72 | NOL4 | nucleolar protein 4 [Source:HGNC Symbol;Acc:HGNC:7870] | 20202 | 0.000 | -0.3601 | No |
| 73 | WIF1 | WNT inhibitory factor 1 [Source:HGNC Symbol;Acc:HGNC:18081] | 20205 | 0.000 | -0.3601 | No |
| 74 | CFAP69 | cilia and flagella associated protein 69 [Source:HGNC Symbol;Acc:HGNC:26107] | 20303 | 0.000 | -0.3628 | No |
| 75 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 20513 | 0.000 | -0.3684 | No |
| 76 | DLGAP2 | DLG associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2906] | 20993 | 0.000 | -0.3814 | No |
| 77 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 21078 | 0.000 | -0.3837 | No |
| 78 | CRTAM | cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:HGNC:24313] | 21281 | 0.000 | -0.3891 | No |
| 79 | FAM153B | family with sequence similarity 153 member B [Source:HGNC Symbol;Acc:HGNC:27323] | 21332 | 0.000 | -0.3905 | No |
| 80 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 21359 | 0.000 | -0.3912 | No |
| 81 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 21630 | 0.000 | -0.3985 | No |
| 82 | LMO3 | LIM domain only 3 [Source:HGNC Symbol;Acc:HGNC:6643] | 21708 | 0.000 | -0.4006 | No |
| 83 | ANK3 | ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494] | 22009 | 0.000 | -0.4087 | No |
| 84 | ADCY1 | adenylate cyclase 1 [Source:HGNC Symbol;Acc:HGNC:232] | 22432 | 0.000 | -0.4201 | No |
| 85 | FGF9 | fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687] | 22457 | 0.000 | -0.4208 | No |
| 86 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 22737 | 0.000 | -0.4283 | No |
| 87 | SOBP | sine oculis binding protein homolog [Source:HGNC Symbol;Acc:HGNC:29256] | 23038 | 0.000 | -0.4364 | No |
| 88 | SLC6A1 | solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042] | 23128 | 0.000 | -0.4388 | No |
| 89 | PLCB1 | phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917] | 23147 | 0.000 | -0.4393 | No |
| 90 | PNMA2 | PNMA family member 2 [Source:HGNC Symbol;Acc:HGNC:9159] | 23619 | 0.000 | -0.4521 | No |
| 91 | MAGEH1 | MAGE family member H1 [Source:HGNC Symbol;Acc:HGNC:24092] | 23867 | 0.000 | -0.4588 | No |
| 92 | A2M | alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7] | 24131 | 0.000 | -0.4659 | No |
| 93 | SLC1A3 | solute carrier family 1 member 3 [Source:HGNC Symbol;Acc:HGNC:10941] | 24187 | 0.000 | -0.4674 | No |
| 94 | PLGLA | plasminogen like A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:9074] | 24239 | 0.000 | -0.4687 | No |
| 95 | AK5 | adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365] | 24375 | 0.000 | -0.4724 | No |
| 96 | RCAN2 | regulator of calcineurin 2 [Source:HGNC Symbol;Acc:HGNC:3041] | 24414 | 0.000 | -0.4734 | No |
| 97 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 24546 | 0.000 | -0.4770 | No |
| 98 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 24659 | 0.000 | -0.4800 | No |
| 99 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 24662 | 0.000 | -0.4801 | No |
| 100 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 24803 | 0.000 | -0.4838 | No |
| 101 | SCN2A | sodium voltage-gated channel alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:10588] | 25008 | 0.000 | -0.4894 | No |
| 102 | MMP27 | matrix metallopeptidase 27 [Source:HGNC Symbol;Acc:HGNC:14250] | 25627 | 0.000 | -0.5061 | No |
| 103 | ARPP21 | cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968] | 25706 | 0.000 | -0.5082 | No |
| 104 | PEG3 | paternally expressed 3 [Source:HGNC Symbol;Acc:HGNC:8826] | 26224 | 0.000 | -0.5222 | No |
| 105 | SATB1 | SATB homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10541] | 26366 | 0.000 | -0.5260 | No |
| 106 | TRIL | TLR4 interactor with leucine rich repeats [Source:HGNC Symbol;Acc:HGNC:22200] | 26530 | 0.000 | -0.5304 | No |
| 107 | ZNF536 | zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] | 26665 | 0.000 | -0.5340 | No |
| 108 | NRCAM | neuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994] | 27581 | 0.000 | -0.5588 | No |
| 109 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 28819 | -0.188 | -0.5898 | No |
| 110 | CPE | carboxypeptidase E [Source:HGNC Symbol;Acc:HGNC:2303] | 29354 | -0.328 | -0.6000 | No |
| 111 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 29481 | -0.362 | -0.5987 | No |
| 112 | SELENOP | selenoprotein P [Source:HGNC Symbol;Acc:HGNC:10751] | 29756 | -0.431 | -0.6005 | No |
| 113 | ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080] | 30292 | -0.552 | -0.6077 | No |
| 114 | KIF5C | kinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325] | 30454 | -0.604 | -0.6042 | No |
| 115 | SCN1B | sodium voltage-gated channel beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:10586] | 30727 | -0.691 | -0.6026 | No |
| 116 | TSPAN7 | tetraspanin 7 [Source:HGNC Symbol;Acc:HGNC:11854] | 32098 | -1.136 | -0.6248 | Yes |
| 117 | TMEM100 | transmembrane protein 100 [Source:HGNC Symbol;Acc:HGNC:25607] | 32163 | -1.163 | -0.6113 | Yes |
| 118 | DUSP6 | dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072] | 32194 | -1.173 | -0.5969 | Yes |
| 119 | GLDC | glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313] | 33222 | -1.543 | -0.6045 | Yes |
| 120 | DNM3 | dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125] | 33462 | -1.650 | -0.5894 | Yes |
| 121 | CDK5R1 | cyclin dependent kinase 5 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:1775] | 33510 | -1.669 | -0.5689 | Yes |
| 122 | TMOD1 | tropomodulin 1 [Source:HGNC Symbol;Acc:HGNC:11871] | 33538 | -1.687 | -0.5476 | Yes |
| 123 | CP | ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295] | 33718 | -1.761 | -0.5295 | Yes |
| 124 | PLP1 | proteolipid protein 1 [Source:HGNC Symbol;Acc:HGNC:9086] | 33764 | -1.787 | -0.5074 | Yes |
| 125 | ANK2 | ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493] | 33915 | -1.876 | -0.4870 | Yes |
| 126 | GATM | glycine amidinotransferase [Source:HGNC Symbol;Acc:HGNC:4175] | 34239 | -2.047 | -0.4690 | Yes |
| 127 | GPR19 | G protein-coupled receptor 19 [Source:HGNC Symbol;Acc:HGNC:4473] | 34610 | -2.237 | -0.4498 | Yes |
| 128 | EMP1 | epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] | 34883 | -2.408 | -0.4258 | Yes |
| 129 | TUBB4A | tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774] | 35449 | -2.796 | -0.4046 | Yes |
| 130 | GPNMB | glycoprotein nmb [Source:HGNC Symbol;Acc:HGNC:4462] | 35520 | -2.863 | -0.3691 | Yes |
| 131 | ATP1A2 | ATPase Na+/K+ transporting subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:800] | 35748 | -3.085 | -0.3350 | Yes |
| 132 | MEF2C | myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996] | 36016 | -3.353 | -0.2984 | Yes |
| 133 | NRN1 | neuritin 1 [Source:HGNC Symbol;Acc:HGNC:17972] | 36237 | -3.552 | -0.2580 | Yes |
| 134 | SORL1 | sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185] | 36481 | -3.844 | -0.2144 | Yes |
| 135 | MAFB | MAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408] | 36630 | -4.036 | -0.1658 | Yes |
| 136 | METTL7A | methyltransferase like 7A [Source:HGNC Symbol;Acc:HGNC:24550] | 36692 | -4.117 | -0.1137 | Yes |
| 137 | TRIM2 | tripartite motif containing 2 [Source:HGNC Symbol;Acc:HGNC:15974] | 37004 | -4.697 | -0.0608 | Yes |
| 138 | SORBS1 | sorbin and SH3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14565] | 37039 | -4.834 | 0.0014 | Yes |
