Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.5316202 |
| Normalized Enrichment Score (NES) | 1.3907734 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.19075032 |
| FWER p-Value | 0.213 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 11 | 4.991 | 0.0320 | Yes |
| 2 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 41 | 4.907 | 0.0629 | Yes |
| 3 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 71 | 4.757 | 0.0929 | Yes |
| 4 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 97 | 4.635 | 0.1222 | Yes |
| 5 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 105 | 4.607 | 0.1518 | Yes |
| 6 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 145 | 4.356 | 0.1789 | Yes |
| 7 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 171 | 4.251 | 0.2058 | Yes |
| 8 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 208 | 4.084 | 0.2312 | Yes |
| 9 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 225 | 4.052 | 0.2570 | Yes |
| 10 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 299 | 3.789 | 0.2795 | Yes |
| 11 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 492 | 3.237 | 0.2953 | Yes |
| 12 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 543 | 3.130 | 0.3142 | Yes |
| 13 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 709 | 2.839 | 0.3281 | Yes |
| 14 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 745 | 2.754 | 0.3449 | Yes |
| 15 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 856 | 2.551 | 0.3584 | Yes |
| 16 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 968 | 2.382 | 0.3708 | Yes |
| 17 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 969 | 2.381 | 0.3862 | Yes |
| 18 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 1010 | 2.308 | 0.4001 | Yes |
| 19 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 1017 | 2.290 | 0.4147 | Yes |
| 20 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 1405 | 1.910 | 0.4166 | Yes |
| 21 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 1482 | 1.827 | 0.4264 | Yes |
| 22 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 1513 | 1.792 | 0.4372 | Yes |
| 23 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 1569 | 1.747 | 0.4470 | Yes |
| 24 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 1626 | 1.695 | 0.4564 | Yes |
| 25 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 1754 | 1.581 | 0.4632 | Yes |
| 26 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 1784 | 1.557 | 0.4725 | Yes |
| 27 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 1882 | 1.478 | 0.4794 | Yes |
| 28 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 2102 | 1.359 | 0.4823 | Yes |
| 29 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 2177 | 1.313 | 0.4888 | Yes |
| 30 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 2208 | 1.293 | 0.4963 | Yes |
| 31 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 2218 | 1.288 | 0.5044 | Yes |
| 32 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 2530 | 1.123 | 0.5033 | Yes |
| 33 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 2531 | 1.123 | 0.5106 | Yes |
| 34 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 2560 | 1.103 | 0.5169 | Yes |
| 35 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 2791 | 0.986 | 0.5171 | Yes |
| 36 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 2803 | 0.976 | 0.5231 | Yes |
| 37 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 3023 | 0.874 | 0.5228 | Yes |
| 38 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3164 | 0.809 | 0.5243 | Yes |
| 39 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 3492 | 0.685 | 0.5199 | Yes |
| 40 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 3502 | 0.682 | 0.5240 | Yes |
| 41 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 3657 | 0.615 | 0.5238 | Yes |
| 42 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3706 | 0.594 | 0.5264 | Yes |
| 43 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 3722 | 0.591 | 0.5298 | Yes |
| 44 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 3791 | 0.565 | 0.5316 | Yes |
| 45 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 3933 | 0.511 | 0.5311 | No |
| 46 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 4036 | 0.475 | 0.5314 | No |
| 47 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 4432 | 0.463 | 0.5237 | No |
| 48 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 4655 | 0.389 | 0.5202 | No |
| 49 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 4672 | 0.383 | 0.5223 | No |
| 50 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 4693 | 0.377 | 0.5242 | No |
| 51 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 4740 | 0.364 | 0.5253 | No |
| 52 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4770 | 0.356 | 0.5268 | No |
| 53 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 4793 | 0.350 | 0.5285 | No |
| 54 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 4954 | 0.298 | 0.5261 | No |
| 55 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 4965 | 0.294 | 0.5277 | No |
| 56 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 5286 | 0.190 | 0.5203 | No |
| 57 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 5899 | 0.019 | 0.5038 | No |
| 58 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 6135 | 0.000 | 0.4975 | No |
| 59 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 8460 | 0.000 | 0.4346 | No |
| 60 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9095 | 0.000 | 0.4175 | No |
| 61 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9455 | 0.000 | 0.4078 | No |
| 62 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9655 | 0.000 | 0.4024 | No |
| 63 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 9727 | 0.000 | 0.4005 | No |
| 64 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 10731 | 0.000 | 0.3733 | No |
| 65 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 10858 | 0.000 | 0.3699 | No |
| 66 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 10900 | 0.000 | 0.3688 | No |
| 67 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11483 | 0.000 | 0.3531 | No |
| 68 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11561 | 0.000 | 0.3510 | No |
| 69 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 11893 | 0.000 | 0.3420 | No |
| 70 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 12057 | 0.000 | 0.3376 | No |
| 71 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12283 | 0.000 | 0.3315 | No |
| 72 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 12839 | 0.000 | 0.3165 | No |
| 73 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13678 | 0.000 | 0.2939 | No |
| 74 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14003 | 0.000 | 0.2851 | No |
| 75 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16288 | 0.000 | 0.2233 | No |
| 76 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17082 | 0.000 | 0.2019 | No |
| 77 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 17975 | 0.000 | 0.1777 | No |
| 78 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19299 | 0.000 | 0.1419 | No |
| 79 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 20641 | 0.000 | 0.1057 | No |
| 80 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 21450 | 0.000 | 0.0838 | No |
| 81 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 21667 | 0.000 | 0.0780 | No |
| 82 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 22100 | 0.000 | 0.0663 | No |
| 83 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 22898 | 0.000 | 0.0447 | No |
| 84 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 23719 | 0.000 | 0.0225 | No |
| 85 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 24133 | 0.000 | 0.0114 | No |
| 86 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 24218 | 0.000 | 0.0091 | No |
| 87 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 24714 | 0.000 | -0.0043 | No |
| 88 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 25710 | 0.000 | -0.0312 | No |
| 89 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 25961 | 0.000 | -0.0380 | No |
| 90 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 26718 | 0.000 | -0.0584 | No |
| 91 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 27675 | 0.000 | -0.0843 | No |
| 92 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 28177 | -0.017 | -0.0977 | No |
| 93 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 28456 | -0.091 | -0.1047 | No |
| 94 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 28681 | -0.153 | -0.1097 | No |
| 95 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 28713 | -0.156 | -0.1096 | No |
| 96 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 29139 | -0.266 | -0.1193 | No |
| 97 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 29904 | -0.470 | -0.1370 | No |
| 98 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 30308 | -0.558 | -0.1443 | No |
| 99 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 30574 | -0.643 | -0.1473 | No |
| 100 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 30644 | -0.666 | -0.1448 | No |
| 101 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 30862 | -0.731 | -0.1460 | No |
| 102 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 31358 | -0.878 | -0.1537 | No |
| 103 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 31682 | -0.986 | -0.1560 | No |
| 104 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 31879 | -1.051 | -0.1545 | No |
| 105 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 32044 | -1.110 | -0.1518 | No |
| 106 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 32306 | -1.225 | -0.1509 | No |
| 107 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 33087 | -1.487 | -0.1624 | No |
| 108 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 33208 | -1.538 | -0.1557 | No |
| 109 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 33292 | -1.572 | -0.1478 | No |
| 110 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 33516 | -1.673 | -0.1430 | No |
| 111 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 33840 | -1.829 | -0.1399 | No |
| 112 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 33869 | -1.848 | -0.1287 | No |
| 113 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 33922 | -1.880 | -0.1180 | No |
| 114 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 34046 | -1.938 | -0.1088 | No |
| 115 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 34450 | -2.127 | -0.1059 | No |
| 116 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 34624 | -2.247 | -0.0960 | No |
| 117 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35454 | -2.801 | -0.1003 | No |
| 118 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 35666 | -3.036 | -0.0864 | No |
| 119 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 36059 | -3.386 | -0.0751 | No |
| 120 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36361 | -3.691 | -0.0594 | No |
| 121 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36440 | -3.801 | -0.0369 | No |
| 122 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 36646 | -4.052 | -0.0163 | No |
| 123 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 36844 | -4.365 | 0.0067 | No |
