Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.701629 |
| Normalized Enrichment Score (NES) | -1.4765956 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.034462262 |
| FWER p-Value | 0.109 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 157 | 4.312 | 0.0163 | No |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 313 | 3.741 | 0.0299 | No |
| 3 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 359 | 3.581 | 0.0457 | No |
| 4 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 768 | 2.702 | 0.0476 | No |
| 5 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 934 | 2.433 | 0.0547 | No |
| 6 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 1686 | 1.657 | 0.0423 | No |
| 7 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 1837 | 1.521 | 0.0455 | No |
| 8 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1865 | 1.496 | 0.0519 | No |
| 9 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 2222 | 1.286 | 0.0483 | No |
| 10 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 2508 | 1.135 | 0.0460 | No |
| 11 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 3114 | 0.834 | 0.0337 | No |
| 12 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 3186 | 0.801 | 0.0355 | No |
| 13 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 4611 | 0.404 | -0.0010 | No |
| 14 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.0294 | No |
| 15 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 5928 | 0.008 | -0.0362 | No |
| 16 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6299 | 0.000 | -0.0462 | No |
| 17 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 6869 | 0.000 | -0.0615 | No |
| 18 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7157 | 0.000 | -0.0693 | No |
| 19 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 7939 | 0.000 | -0.0904 | No |
| 20 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8563 | 0.000 | -0.1073 | No |
| 21 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 8968 | 0.000 | -0.1182 | No |
| 22 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9588 | 0.000 | -0.1350 | No |
| 23 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 9590 | 0.000 | -0.1350 | No |
| 24 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9693 | 0.000 | -0.1377 | No |
| 25 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10469 | 0.000 | -0.1587 | No |
| 26 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11317 | 0.000 | -0.1816 | No |
| 27 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12350 | 0.000 | -0.2095 | No |
| 28 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13251 | 0.000 | -0.2339 | No |
| 29 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 13751 | 0.000 | -0.2474 | No |
| 30 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14494 | 0.000 | -0.2674 | No |
| 31 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 15301 | 0.000 | -0.2892 | No |
| 32 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15941 | 0.000 | -0.3065 | No |
| 33 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16640 | 0.000 | -0.3254 | No |
| 34 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17015 | 0.000 | -0.3355 | No |
| 35 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19793 | 0.000 | -0.4106 | No |
| 36 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 20513 | 0.000 | -0.4300 | No |
| 37 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 21078 | 0.000 | -0.4453 | No |
| 38 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 22016 | 0.000 | -0.4706 | No |
| 39 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 22995 | 0.000 | -0.4971 | No |
| 40 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 24938 | 0.000 | -0.5496 | No |
| 41 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26705 | 0.000 | -0.5974 | No |
| 42 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 29336 | -0.323 | -0.6670 | No |
| 43 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 30290 | -0.551 | -0.6901 | No |
| 44 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 30334 | -0.565 | -0.6886 | No |
| 45 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 30386 | -0.581 | -0.6872 | No |
| 46 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 30782 | -0.705 | -0.6945 | No |
| 47 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 30939 | -0.749 | -0.6952 | No |
| 48 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 31178 | -0.818 | -0.6977 | Yes |
| 49 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 31238 | -0.841 | -0.6953 | Yes |
| 50 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 31361 | -0.879 | -0.6944 | Yes |
| 51 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 31553 | -0.938 | -0.6951 | Yes |
| 52 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 31724 | -1.000 | -0.6950 | Yes |
| 53 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 31851 | -1.041 | -0.6934 | Yes |
| 54 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 31980 | -1.085 | -0.6917 | Yes |
| 55 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.6929 | Yes |
| 56 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 32313 | -1.227 | -0.6891 | Yes |
| 57 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 32578 | -1.258 | -0.6903 | Yes |
| 58 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 32583 | -1.260 | -0.6844 | Yes |
| 59 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 32606 | -1.270 | -0.6790 | Yes |
| 60 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 32609 | -1.272 | -0.6730 | Yes |
| 61 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 32685 | -1.314 | -0.6687 | Yes |
| 62 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 32980 | -1.442 | -0.6698 | Yes |
| 63 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 33059 | -1.477 | -0.6649 | Yes |
| 64 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 33176 | -1.519 | -0.6608 | Yes |
| 65 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.6567 | Yes |
| 66 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 33518 | -1.673 | -0.6545 | Yes |
| 67 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 33990 | -1.909 | -0.6582 | Yes |
| 68 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 34005 | -1.918 | -0.6494 | Yes |
| 69 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 34194 | -2.021 | -0.6449 | Yes |
| 70 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 34314 | -2.089 | -0.6381 | Yes |
| 71 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34358 | -2.126 | -0.6292 | Yes |
| 72 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 34455 | -2.128 | -0.6216 | Yes |
| 73 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 34462 | -2.130 | -0.6117 | Yes |
| 74 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 34493 | -2.151 | -0.6022 | Yes |
| 75 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 34630 | -2.251 | -0.5952 | Yes |
| 76 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 34724 | -2.303 | -0.5867 | Yes |
| 77 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 34862 | -2.397 | -0.5790 | Yes |
| 78 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 34896 | -2.419 | -0.5684 | Yes |
| 79 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 34948 | -2.444 | -0.5581 | Yes |
| 80 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 35065 | -2.535 | -0.5492 | Yes |
| 81 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.5372 | Yes |
| 82 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 35111 | -2.566 | -0.5261 | Yes |
| 83 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 35218 | -2.664 | -0.5163 | Yes |
| 84 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 35253 | -2.679 | -0.5044 | Yes |
| 85 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 35307 | -2.689 | -0.4931 | Yes |
| 86 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 35408 | -2.762 | -0.4826 | Yes |
| 87 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 35502 | -2.845 | -0.4716 | Yes |
| 88 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 35509 | -2.852 | -0.4582 | Yes |
| 89 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35534 | -2.879 | -0.4451 | Yes |
| 90 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 35544 | -2.882 | -0.4316 | Yes |
| 91 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35545 | -2.882 | -0.4179 | Yes |
| 92 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 35586 | -2.936 | -0.4050 | Yes |
| 93 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35624 | -2.974 | -0.3918 | Yes |
| 94 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35673 | -3.046 | -0.3786 | Yes |
| 95 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35677 | -3.050 | -0.3642 | Yes |
| 96 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.3522 | Yes |
| 97 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 36017 | -3.355 | -0.3425 | Yes |
| 98 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.3270 | Yes |
| 99 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 36055 | -3.384 | -0.3113 | Yes |
| 100 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 36069 | -3.397 | -0.2955 | Yes |
| 101 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 36084 | -3.417 | -0.2796 | Yes |
| 102 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36119 | -3.455 | -0.2641 | Yes |
| 103 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36157 | -3.491 | -0.2484 | Yes |
| 104 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36288 | -3.614 | -0.2347 | Yes |
| 105 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 36344 | -3.686 | -0.2187 | Yes |
| 106 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36406 | -3.765 | -0.2024 | Yes |
| 107 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36446 | -3.807 | -0.1853 | Yes |
| 108 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 36466 | -3.829 | -0.1676 | Yes |
| 109 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36553 | -3.943 | -0.1511 | Yes |
| 110 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36637 | -4.046 | -0.1341 | Yes |
| 111 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36735 | -4.169 | -0.1169 | Yes |
| 112 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 36767 | -4.212 | -0.0977 | Yes |
| 113 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.0780 | Yes |
| 114 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 36791 | -4.254 | -0.0578 | Yes |
| 115 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36911 | -4.479 | -0.0397 | Yes |
| 116 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36967 | -4.606 | -0.0193 | Yes |
| 117 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 37018 | -4.741 | 0.0019 | Yes |
