Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.72037464 |
| Normalized Enrichment Score (NES) | -1.5349354 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021981776 |
| FWER p-Value | 0.024 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 226 | 4.041 | 0.0117 | No |
| 2 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 390 | 3.514 | 0.0228 | No |
| 3 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 556 | 3.095 | 0.0319 | No |
| 4 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 750 | 2.742 | 0.0388 | No |
| 5 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 939 | 2.426 | 0.0444 | No |
| 6 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 1183 | 2.075 | 0.0470 | No |
| 7 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1694 | 1.650 | 0.0404 | No |
| 8 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 1800 | 1.544 | 0.0444 | No |
| 9 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 2313 | 1.238 | 0.0360 | No |
| 10 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 3189 | 0.799 | 0.0159 | No |
| 11 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 3336 | 0.747 | 0.0152 | No |
| 12 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 5676 | 0.088 | -0.0477 | No |
| 13 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6369 | 0.000 | -0.0664 | No |
| 14 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 7799 | 0.000 | -0.1051 | No |
| 15 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9379 | 0.000 | -0.1478 | No |
| 16 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 9422 | 0.000 | -0.1489 | No |
| 17 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10300 | 0.000 | -0.1727 | No |
| 18 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 11843 | 0.000 | -0.2144 | No |
| 19 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12242 | 0.000 | -0.2251 | No |
| 20 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12391 | 0.000 | -0.2292 | No |
| 21 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 12402 | 0.000 | -0.2294 | No |
| 22 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12435 | 0.000 | -0.2303 | No |
| 23 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12709 | 0.000 | -0.2377 | No |
| 24 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 12710 | 0.000 | -0.2377 | No |
| 25 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13323 | 0.000 | -0.2542 | No |
| 26 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 13653 | 0.000 | -0.2631 | No |
| 27 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14646 | 0.000 | -0.2900 | No |
| 28 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 15439 | 0.000 | -0.3114 | No |
| 29 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 15450 | 0.000 | -0.3117 | No |
| 30 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 15941 | 0.000 | -0.3249 | No |
| 31 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16183 | 0.000 | -0.3315 | No |
| 32 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16260 | 0.000 | -0.3335 | No |
| 33 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16413 | 0.000 | -0.3376 | No |
| 34 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16515 | 0.000 | -0.3404 | No |
| 35 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 16942 | 0.000 | -0.3519 | No |
| 36 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17486 | 0.000 | -0.3666 | No |
| 37 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18732 | 0.000 | -0.4003 | No |
| 38 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18733 | 0.000 | -0.4003 | No |
| 39 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 19008 | 0.000 | -0.4077 | No |
| 40 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19697 | 0.000 | -0.4263 | No |
| 41 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19845 | 0.000 | -0.4303 | No |
| 42 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 21041 | 0.000 | -0.4626 | No |
| 43 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 21248 | 0.000 | -0.4682 | No |
| 44 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 21563 | 0.000 | -0.4767 | No |
| 45 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 22751 | 0.000 | -0.5088 | No |
| 46 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 25065 | 0.000 | -0.5714 | No |
| 47 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 25548 | 0.000 | -0.5844 | No |
| 48 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 25912 | 0.000 | -0.5942 | No |
| 49 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 26154 | 0.000 | -0.6007 | No |
| 50 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 26408 | 0.000 | -0.6076 | No |
| 51 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26705 | 0.000 | -0.6156 | No |
| 52 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 27316 | 0.000 | -0.6321 | No |
| 53 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 28131 | -0.005 | -0.6541 | No |
| 54 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 28663 | -0.147 | -0.6678 | No |
| 55 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 28827 | -0.191 | -0.6714 | No |
| 56 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 28918 | -0.211 | -0.6729 | No |
| 57 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 29425 | -0.347 | -0.6850 | No |
| 58 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 29481 | -0.362 | -0.6849 | No |
| 59 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 29735 | -0.425 | -0.6899 | No |
| 60 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 30110 | -0.529 | -0.6977 | No |
| 61 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 30403 | -0.587 | -0.7030 | No |
| 62 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 30451 | -0.602 | -0.7016 | No |
| 63 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 30973 | -0.758 | -0.7124 | No |
| 64 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 30989 | -0.765 | -0.7094 | No |
| 65 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31036 | -0.782 | -0.7072 | No |
| 66 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31333 | -0.870 | -0.7114 | No |
| 67 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 31377 | -0.884 | -0.7087 | No |
| 68 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 31421 | -0.901 | -0.7059 | No |
| 69 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 31553 | -0.938 | -0.7053 | No |
| 70 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 31737 | -1.003 | -0.7058 | No |
| 71 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 31785 | -1.020 | -0.7026 | No |
| 72 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32234 | -1.194 | -0.7094 | No |
| 73 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 32483 | -1.232 | -0.7107 | No |
| 74 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 32822 | -1.363 | -0.7138 | Yes |
| 75 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 33009 | -1.453 | -0.7125 | Yes |
| 76 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33302 | -1.578 | -0.7134 | Yes |
| 77 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 33526 | -1.678 | -0.7121 | Yes |
| 78 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 33613 | -1.728 | -0.7068 | Yes |
| 79 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33804 | -1.813 | -0.7039 | Yes |
| 80 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34358 | -2.126 | -0.7095 | Yes |
| 81 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 34498 | -2.155 | -0.7038 | Yes |
| 82 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 34656 | -2.264 | -0.6981 | Yes |
| 83 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34953 | -2.448 | -0.6953 | Yes |
| 84 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35069 | -2.538 | -0.6872 | Yes |
| 85 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35160 | -2.606 | -0.6781 | Yes |
| 86 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 35210 | -2.659 | -0.6678 | Yes |
| 87 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 35325 | -2.700 | -0.6589 | Yes |
| 88 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 35370 | -2.733 | -0.6481 | Yes |
| 89 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35403 | -2.757 | -0.6368 | Yes |
| 90 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 35443 | -2.791 | -0.6256 | Yes |
| 91 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35534 | -2.879 | -0.6153 | Yes |
| 92 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35545 | -2.882 | -0.6029 | Yes |
| 93 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35623 | -2.974 | -0.5919 | Yes |
| 94 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35673 | -3.046 | -0.5798 | Yes |
| 95 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35740 | -3.078 | -0.5680 | Yes |
| 96 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 35779 | -3.118 | -0.5553 | Yes |
| 97 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 35783 | -3.122 | -0.5416 | Yes |
| 98 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 35793 | -3.134 | -0.5280 | Yes |
| 99 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 35844 | -3.180 | -0.5154 | Yes |
| 100 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36039 | -3.372 | -0.5057 | Yes |
| 101 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 36069 | -3.397 | -0.4916 | Yes |
| 102 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36106 | -3.443 | -0.4774 | Yes |
| 103 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36128 | -3.460 | -0.4627 | Yes |
| 104 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36157 | -3.491 | -0.4481 | Yes |
| 105 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36167 | -3.496 | -0.4329 | Yes |
| 106 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 36189 | -3.522 | -0.4179 | Yes |
| 107 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 36233 | -3.545 | -0.4035 | Yes |
| 108 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36324 | -3.663 | -0.3898 | Yes |
| 109 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36371 | -3.711 | -0.3747 | Yes |
| 110 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36406 | -3.765 | -0.3590 | Yes |
| 111 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36519 | -3.907 | -0.3448 | Yes |
| 112 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36562 | -3.957 | -0.3285 | Yes |
| 113 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36590 | -3.998 | -0.3116 | Yes |
| 114 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36595 | -4.006 | -0.2941 | Yes |
| 115 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36639 | -4.048 | -0.2774 | Yes |
| 116 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36713 | -4.143 | -0.2611 | Yes |
| 117 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36735 | -4.169 | -0.2433 | Yes |
| 118 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36744 | -4.182 | -0.2251 | Yes |
| 119 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36753 | -4.198 | -0.2068 | Yes |
| 120 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36769 | -4.215 | -0.1886 | Yes |
| 121 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36781 | -4.232 | -0.1703 | Yes |
| 122 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36786 | -4.241 | -0.1517 | Yes |
| 123 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36803 | -4.278 | -0.1333 | Yes |
| 124 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 36846 | -4.370 | -0.1152 | Yes |
| 125 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36884 | -4.436 | -0.0966 | Yes |
| 126 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36887 | -4.439 | -0.0771 | Yes |
| 127 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 36910 | -4.478 | -0.0580 | Yes |
| 128 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36967 | -4.606 | -0.0392 | Yes |
| 129 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36994 | -4.675 | -0.0193 | Yes |
| 130 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 37082 | -4.961 | 0.0002 | Yes |
