Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P130_DN.V1_UP |
| Enrichment Score (ES) | -0.60744953 |
| Normalized Enrichment Score (NES) | -1.2996209 |
| Nominal p-value | 0.022727273 |
| FDR q-value | 0.20883317 |
| FWER p-Value | 0.979 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 202 | 4.113 | 0.0188 | No |
| 2 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 259 | 3.897 | 0.0403 | No |
| 3 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 278 | 3.840 | 0.0625 | No |
| 4 | COL11A2 | collagen type XI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2187] | 651 | 2.864 | 0.0694 | No |
| 5 | LITAF | lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841] | 781 | 2.681 | 0.0817 | No |
| 6 | HMGA2 | high mobility group AT-hook 2 [Source:HGNC Symbol;Acc:HGNC:5009] | 805 | 2.638 | 0.0967 | No |
| 7 | FST | follistatin [Source:HGNC Symbol;Acc:HGNC:3971] | 1701 | 1.639 | 0.0821 | No |
| 8 | CASP7 | caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508] | 1743 | 1.591 | 0.0904 | No |
| 9 | AVP | arginine vasopressin [Source:HGNC Symbol;Acc:HGNC:894] | 1772 | 1.567 | 0.0989 | No |
| 10 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | 1805 | 1.539 | 0.1071 | No |
| 11 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 1886 | 1.476 | 0.1137 | No |
| 12 | QTRT1 | queuine tRNA-ribosyltransferase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:23797] | 2311 | 1.239 | 0.1095 | No |
| 13 | FAM220A | family with sequence similarity 220 member A [Source:HGNC Symbol;Acc:HGNC:22422] | 2952 | 0.905 | 0.0976 | No |
| 14 | TRAF2 | TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032] | 3326 | 0.751 | 0.0919 | No |
| 15 | ZBTB17 | zinc finger and BTB domain containing 17 [Source:HGNC Symbol;Acc:HGNC:12936] | 3601 | 0.640 | 0.0883 | No |
| 16 | CYBA | cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577] | 3813 | 0.558 | 0.0859 | No |
| 17 | LSM4 | LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17259] | 4434 | 0.463 | 0.0718 | No |
| 18 | MIGA2 | mitoguardin 2 [Source:HGNC Symbol;Acc:HGNC:23621] | 4449 | 0.458 | 0.0741 | No |
| 19 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:811] | 4795 | 0.349 | 0.0669 | No |
| 20 | MBD3 | methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:HGNC:6918] | 4962 | 0.295 | 0.0641 | No |
| 21 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153] | 5352 | 0.173 | 0.0546 | No |
| 22 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 5751 | 0.065 | 0.0442 | No |
| 23 | C11orf71 | chromosome 11 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:25937] | 6010 | 0.000 | 0.0372 | No |
| 24 | VSIG2 | V-set and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17149] | 6124 | 0.000 | 0.0342 | No |
| 25 | MYOZ2 | myozenin 2 [Source:HGNC Symbol;Acc:HGNC:1330] | 6127 | 0.000 | 0.0341 | No |
| 26 | USP13 | ubiquitin specific peptidase 13 [Source:HGNC Symbol;Acc:HGNC:12611] | 6245 | 0.000 | 0.0310 | No |
| 27 | FGF10 | fibroblast growth factor 10 [Source:HGNC Symbol;Acc:HGNC:3666] | 6569 | 0.000 | 0.0222 | No |
| 28 | AQP5 | aquaporin 5 [Source:HGNC Symbol;Acc:HGNC:638] | 6730 | 0.000 | 0.0179 | No |
| 29 | ART1 | ADP-ribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:723] | 7138 | 0.000 | 0.0069 | No |
| 30 | GREM2 | gremlin 2, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:17655] | 7931 | 0.000 | -0.0145 | No |
| 31 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8080 | 0.000 | -0.0185 | No |
| 32 | SIM2 | SIM bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10883] | 8081 | 0.000 | -0.0185 | No |
| 33 | B4GALT4 | beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927] | 9332 | 0.000 | -0.0524 | No |
| 34 | PIWIL1 | piwi like RNA-mediated gene silencing 1 [Source:HGNC Symbol;Acc:HGNC:9007] | 9528 | 0.000 | -0.0576 | No |
| 35 | SLC22A3 | solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967] | 9909 | 0.000 | -0.0679 | No |
| 36 | FAM187A | family with sequence similarity 187 member A [Source:HGNC Symbol;Acc:HGNC:35153] | 10540 | 0.000 | -0.0850 | No |
| 37 | CRLF1 | cytokine receptor like factor 1 [Source:HGNC Symbol;Acc:HGNC:2364] | 10664 | 0.000 | -0.0883 | No |
| 38 | NKD2 | NKD inhibitor of WNT signaling pathway 2 [Source:HGNC Symbol;Acc:HGNC:17046] | 11026 | 0.000 | -0.0981 | No |
| 39 | PDZK1 | PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:8821] | 11109 | 0.000 | -0.1003 | No |
| 40 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 14236 | 0.000 | -0.1848 | No |
| 41 | MYLK | myosin light chain kinase [Source:HGNC Symbol;Acc:HGNC:7590] | 14252 | 0.000 | -0.1853 | No |
| 42 | NXNL1 | nucleoredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:25179] | 14693 | 0.000 | -0.1972 | No |
| 43 | RHOJ | ras homolog family member J [Source:HGNC Symbol;Acc:HGNC:688] | 14969 | 0.000 | -0.2046 | No |
| 44 | GC | GC vitamin D binding protein [Source:HGNC Symbol;Acc:HGNC:4187] | 16091 | 0.000 | -0.2349 | No |
| 45 | PCSK5 | proprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acc:HGNC:8747] | 16195 | 0.000 | -0.2377 | No |
| 46 | SLC7A9 | solute carrier family 7 member 9 [Source:HGNC Symbol;Acc:HGNC:11067] | 16691 | 0.000 | -0.2511 | No |
| 47 | CRTAC1 | cartilage acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:14882] | 16837 | 0.000 | -0.2550 | No |
| 48 | TEAD1 | TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714] | 17095 | 0.000 | -0.2620 | No |
| 49 | TWIST2 | twist family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:20670] | 17197 | 0.000 | -0.2647 | No |
| 50 | TINAG | tubulointerstitial nephritis antigen [Source:HGNC Symbol;Acc:HGNC:14599] | 17234 | 0.000 | -0.2657 | No |
| 51 | KAZN | kazrin, periplakin interacting protein [Source:HGNC Symbol;Acc:HGNC:29173] | 17329 | 0.000 | -0.2682 | No |
| 52 | SEMA5B | semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737] | 17812 | 0.000 | -0.2813 | No |
| 53 | NKX2-8 | NK2 homeobox 8 [Source:HGNC Symbol;Acc:HGNC:16364] | 19202 | 0.000 | -0.3188 | No |
| 54 | FOXI1 | forkhead box I1 [Source:HGNC Symbol;Acc:HGNC:3815] | 20507 | 0.000 | -0.3541 | No |
| 55 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 20579 | 0.000 | -0.3560 | No |
| 56 | SULT1B1 | sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845] | 20969 | 0.000 | -0.3666 | No |
| 57 | CRB3 | crumbs cell polarity complex component 3 [Source:HGNC Symbol;Acc:HGNC:20237] | 21057 | 0.000 | -0.3689 | No |
| 58 | WNT2B | Wnt family member 2B [Source:HGNC Symbol;Acc:HGNC:12781] | 21762 | 0.000 | -0.3880 | No |
| 59 | SPATA13 | spermatogenesis associated 13 [Source:HGNC Symbol;Acc:HGNC:23222] | 22014 | 0.000 | -0.3948 | No |
| 60 | STMN3 | stathmin 3 [Source:HGNC Symbol;Acc:HGNC:15926] | 24238 | 0.000 | -0.4549 | No |
| 61 | ALK | ALK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:427] | 24420 | 0.000 | -0.4598 | No |
| 62 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 24679 | 0.000 | -0.4668 | No |
| 63 | DUSP13 | dual specificity phosphatase 13 [Source:HGNC Symbol;Acc:HGNC:19681] | 25327 | 0.000 | -0.4843 | No |
| 64 | CACNG4 | calcium voltage-gated channel auxiliary subunit gamma 4 [Source:HGNC Symbol;Acc:HGNC:1408] | 25359 | 0.000 | -0.4851 | No |
| 65 | RSPH9 | radial spoke head component 9 [Source:HGNC Symbol;Acc:HGNC:21057] | 27229 | 0.000 | -0.5357 | No |
| 66 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 27788 | 0.000 | -0.5508 | No |
| 67 | RENBP | renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959] | 28438 | -0.086 | -0.5678 | No |
| 68 | HINT1 | histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912] | 28846 | -0.195 | -0.5777 | No |
| 69 | GLIS2 | GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450] | 28930 | -0.213 | -0.5787 | No |
| 70 | SLC13A2 | solute carrier family 13 member 2 [Source:HGNC Symbol;Acc:HGNC:10917] | 29470 | -0.359 | -0.5911 | No |
| 71 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 29570 | -0.378 | -0.5916 | No |
| 72 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 29593 | -0.385 | -0.5899 | No |
| 73 | EFTUD2 | elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858] | 29615 | -0.393 | -0.5882 | No |
| 74 | CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314] | 29634 | -0.398 | -0.5863 | No |
| 75 | POLR2I | RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196] | 29782 | -0.437 | -0.5877 | No |
| 76 | SNN | stannin [Source:HGNC Symbol;Acc:HGNC:11149] | 29847 | -0.455 | -0.5867 | No |
| 77 | GPN3 | GPN-loop GTPase 3 [Source:HGNC Symbol;Acc:HGNC:30186] | 29911 | -0.472 | -0.5857 | No |
| 78 | EXOSC2 | exosome component 2 [Source:HGNC Symbol;Acc:HGNC:17097] | 29990 | -0.498 | -0.5848 | No |
| 79 | STAT5B | signal transducer and activator of transcription 5B [Source:HGNC Symbol;Acc:HGNC:11367] | 30600 | -0.650 | -0.5975 | No |
| 80 | EIF1B | eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:HGNC:30792] | 30815 | -0.714 | -0.5990 | No |
| 81 | RASA4 | RAS p21 protein activator 4 [Source:HGNC Symbol;Acc:HGNC:23181] | 31127 | -0.800 | -0.6027 | Yes |
| 82 | CUEDC2 | CUE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28352] | 31301 | -0.863 | -0.6023 | Yes |
| 83 | RIPK3 | receptor interacting serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:10021] | 31349 | -0.875 | -0.5984 | Yes |
| 84 | SDF2L1 | stromal cell derived factor 2 like 1 [Source:HGNC Symbol;Acc:HGNC:10676] | 31392 | -0.891 | -0.5943 | Yes |
| 85 | ERG | ETS transcription factor ERG [Source:HGNC Symbol;Acc:HGNC:3446] | 31493 | -0.915 | -0.5916 | Yes |
| 86 | ELOF1 | elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691] | 31688 | -0.987 | -0.5910 | Yes |
| 87 | CARD19 | caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] | 32080 | -1.129 | -0.5949 | Yes |
| 88 | PARS2 | prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563] | 32223 | -1.187 | -0.5918 | Yes |
| 89 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 32455 | -1.232 | -0.5907 | Yes |
| 90 | CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28184] | 32539 | -1.241 | -0.5856 | Yes |
| 91 | RUVBL2 | RuvB like AAA ATPase 2 [Source:HGNC Symbol;Acc:HGNC:10475] | 32561 | -1.252 | -0.5788 | Yes |
| 92 | CMTM7 | CKLF like MARVEL transmembrane domain containing 7 [Source:HGNC Symbol;Acc:HGNC:19178] | 32859 | -1.379 | -0.5787 | Yes |
| 93 | GFER | growth factor, augmenter of liver regeneration [Source:HGNC Symbol;Acc:HGNC:4236] | 33237 | -1.549 | -0.5798 | Yes |
| 94 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.5722 | Yes |
| 95 | ANAPC5 | anaphase promoting complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:15713] | 33415 | -1.626 | -0.5656 | Yes |
| 96 | MYG1 | MYG1 exonuclease [Source:HGNC Symbol;Acc:HGNC:17590] | 33479 | -1.655 | -0.5575 | Yes |
| 97 | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:29897] | 33942 | -1.880 | -0.5589 | Yes |
| 98 | POLD2 | DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176] | 34143 | -1.990 | -0.5526 | Yes |
| 99 | MRAS | muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227] | 34258 | -2.058 | -0.5435 | Yes |
| 100 | ABCG4 | ATP binding cassette subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:13884] | 34517 | -2.172 | -0.5377 | Yes |
| 101 | SELENOH | selenoprotein H [Source:HGNC Symbol;Acc:HGNC:18251] | 34771 | -2.332 | -0.5308 | Yes |
| 102 | SGSM3 | small G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:25228] | 34892 | -2.414 | -0.5197 | Yes |
| 103 | SEMA6B | semaphorin 6B [Source:HGNC Symbol;Acc:HGNC:10739] | 35051 | -2.527 | -0.5091 | Yes |
| 104 | COQ8A | coenzyme Q8A [Source:HGNC Symbol;Acc:HGNC:16812] | 35091 | -2.555 | -0.4951 | Yes |
| 105 | ZNF428 | zinc finger protein 428 [Source:HGNC Symbol;Acc:HGNC:20804] | 35241 | -2.677 | -0.4833 | Yes |
| 106 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 35348 | -2.720 | -0.4701 | Yes |
| 107 | ORC1 | origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487] | 35382 | -2.741 | -0.4548 | Yes |
| 108 | SLC43A3 | solute carrier family 43 member 3 [Source:HGNC Symbol;Acc:HGNC:17466] | 35511 | -2.854 | -0.4414 | Yes |
| 109 | ICA1 | islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343] | 35641 | -3.000 | -0.4272 | Yes |
| 110 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35837 | -3.176 | -0.4137 | Yes |
| 111 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36110 | -3.445 | -0.4007 | Yes |
| 112 | FADS2 | fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] | 36140 | -3.471 | -0.3810 | Yes |
| 113 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.3607 | Yes |
| 114 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 36334 | -3.680 | -0.3439 | Yes |
| 115 | OXLD1 | oxidoreductase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27901] | 36357 | -3.687 | -0.3227 | Yes |
| 116 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36379 | -3.721 | -0.3013 | Yes |
| 117 | ZBTB12 | zinc finger and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:19066] | 36383 | -3.724 | -0.2794 | Yes |
| 118 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36572 | -3.970 | -0.2610 | Yes |
| 119 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36589 | -3.996 | -0.2378 | Yes |
| 120 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36605 | -4.013 | -0.2146 | Yes |
| 121 | TRAF4 | TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034] | 36610 | -4.020 | -0.1909 | Yes |
| 122 | HYAL3 | hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] | 36611 | -4.020 | -0.1672 | Yes |
| 123 | PIMREG | PICALM interacting mitotic regulator [Source:HGNC Symbol;Acc:HGNC:25483] | 36627 | -4.035 | -0.1438 | Yes |
| 124 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813] | 36698 | -4.122 | -0.1213 | Yes |
| 125 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.0972 | Yes |
| 126 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36747 | -4.186 | -0.0734 | Yes |
| 127 | GRTP1 | growth hormone regulated TBC protein 1 [Source:HGNC Symbol;Acc:HGNC:20310] | 36954 | -4.571 | -0.0520 | Yes |
| 128 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37007 | -4.708 | -0.0256 | Yes |
| 129 | SNTA1 | syntrophin alpha 1 [Source:HGNC Symbol;Acc:HGNC:11167] | 37008 | -4.714 | 0.0022 | Yes |
