Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | DESCARTES_FETAL_SPLEEN_MYELOID_CELLS |
| Enrichment Score (ES) | 0.6243362 |
| Normalized Enrichment Score (NES) | 1.638535 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.104364105 |
| FWER p-Value | 0.256 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 3 | 4.998 | 0.0378 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 15 | 4.978 | 0.0751 | Yes |
| 3 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 78 | 4.727 | 0.1093 | Yes |
| 4 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 80 | 4.725 | 0.1450 | Yes |
| 5 | MNDA | myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183] | 81 | 4.707 | 0.1806 | Yes |
| 6 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 195 | 4.142 | 0.2089 | Yes |
| 7 | KCNAB1 | potassium voltage-gated channel subfamily A member regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6228] | 206 | 4.086 | 0.2396 | Yes |
| 8 | RGS1 | regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991] | 227 | 4.037 | 0.2696 | Yes |
| 9 | NLRP3 | NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400] | 245 | 3.970 | 0.2992 | Yes |
| 10 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 290 | 3.811 | 0.3269 | Yes |
| 11 | LY96 | lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156] | 301 | 3.789 | 0.3553 | Yes |
| 12 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 422 | 3.383 | 0.3777 | Yes |
| 13 | OSM | oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506] | 425 | 3.363 | 0.4031 | Yes |
| 14 | NABP1 | nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232] | 446 | 3.300 | 0.4275 | Yes |
| 15 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 534 | 3.141 | 0.4490 | Yes |
| 16 | ADAP2 | ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487] | 562 | 3.082 | 0.4716 | Yes |
| 17 | ANKRD24 | ankyrin repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:29424] | 614 | 2.963 | 0.4926 | Yes |
| 18 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 620 | 2.949 | 0.5148 | Yes |
| 19 | CD274 | CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635] | 676 | 2.839 | 0.5348 | Yes |
| 20 | NOD2 | nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331] | 819 | 2.618 | 0.5508 | Yes |
| 21 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 828 | 2.609 | 0.5703 | Yes |
| 22 | RASSF4 | Ras association domain family member 4 [Source:HGNC Symbol;Acc:HGNC:20793] | 1404 | 1.911 | 0.5692 | Yes |
| 23 | PRAM1 | PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091] | 1816 | 1.531 | 0.5697 | Yes |
| 24 | SMIM35 | small integral membrane protein 35 [Source:HGNC Symbol;Acc:HGNC:44179] | 1908 | 1.460 | 0.5783 | Yes |
| 25 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 1912 | 1.458 | 0.5893 | Yes |
| 26 | ITGAD | integrin subunit alpha D [Source:HGNC Symbol;Acc:HGNC:6146] | 2080 | 1.375 | 0.5952 | Yes |
| 27 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 2119 | 1.347 | 0.6043 | Yes |
| 28 | PID1 | phosphotyrosine interaction domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26084] | 2184 | 1.307 | 0.6125 | Yes |
| 29 | FABP5 | fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560] | 2381 | 1.201 | 0.6163 | Yes |
| 30 | SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 [Source:HGNC Symbol;Acc:HGNC:10528] | 2608 | 1.072 | 0.6183 | Yes |
| 31 | NCF2 | neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661] | 2887 | 0.932 | 0.6178 | Yes |
| 32 | NAIP | NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634] | 3099 | 0.838 | 0.6185 | Yes |
| 33 | THEMIS2 | thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] | 3116 | 0.832 | 0.6243 | Yes |
| 34 | ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:3357] | 3804 | 0.561 | 0.6100 | No |
| 35 | ITGAX | integrin subunit alpha X [Source:HGNC Symbol;Acc:HGNC:6152] | 4224 | 0.473 | 0.6022 | No |
| 36 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 5928 | 0.008 | 0.5562 | No |
| 37 | VSIG4 | V-set and immunoglobulin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:17032] | 6126 | 0.000 | 0.5509 | No |
| 38 | LINC01645 | long intergenic non-protein coding RNA 1645 [Source:HGNC Symbol;Acc:HGNC:52432] | 6941 | 0.000 | 0.5289 | No |
| 39 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7418 | 0.000 | 0.5160 | No |
| 40 | EPB41L3 | erythrocyte membrane protein band 4.1 like 3 [Source:HGNC Symbol;Acc:HGNC:3380] | 7697 | 0.000 | 0.5085 | No |
| 41 | RASGEF1C | RasGEF domain family member 1C [Source:HGNC Symbol;Acc:HGNC:27400] | 7920 | 0.000 | 0.5025 | No |
| 42 | FCAR | Fc fragment of IgA receptor [Source:HGNC Symbol;Acc:HGNC:3608] | 8025 | 0.000 | 0.4997 | No |
| 43 | FCN1 | ficolin 1 [Source:HGNC Symbol;Acc:HGNC:3623] | 8102 | 0.000 | 0.4976 | No |
| 44 | AL606970.3 | novel transcript | 8106 | 0.000 | 0.4975 | No |
| 45 | BATF3 | basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915] | 8577 | 0.000 | 0.4848 | No |
| 46 | CLEC7A | C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558] | 9181 | 0.000 | 0.4685 | No |
| 47 | CARD14 | caspase recruitment domain family member 14 [Source:HGNC Symbol;Acc:HGNC:16446] | 9659 | 0.000 | 0.4556 | No |
| 48 | ADGRE4P | adhesion G protein-coupled receptor E4, pseudogene [Source:HGNC Symbol;Acc:HGNC:19240] | 10307 | 0.000 | 0.4381 | No |
| 49 | CHN2 | chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944] | 10375 | 0.000 | 0.4363 | No |
| 50 | IGSF21 | immunoglobin superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:28246] | 10679 | 0.000 | 0.4281 | No |
| 51 | MS4A7 | membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378] | 10827 | 0.000 | 0.4241 | No |
| 52 | FCGR1A | Fc fragment of IgG receptor Ia [Source:HGNC Symbol;Acc:HGNC:3613] | 11262 | 0.000 | 0.4124 | No |
| 53 | S100Z | S100 calcium binding protein Z [Source:HGNC Symbol;Acc:HGNC:30367] | 11444 | 0.000 | 0.4075 | No |
| 54 | CLNK | cytokine dependent hematopoietic cell linker [Source:HGNC Symbol;Acc:HGNC:17438] | 11446 | 0.000 | 0.4074 | No |
| 55 | SIGLEC16 | sialic acid binding Ig like lectin 16 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:24851] | 11658 | 0.000 | 0.4017 | No |
| 56 | CSF2RA | colony stimulating factor 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:2435] | 11737 | 0.000 | 0.3996 | No |
| 57 | AGR2 | anterior gradient 2, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:328] | 11890 | 0.000 | 0.3955 | No |
| 58 | LINC00996 | long intergenic non-protein coding RNA 996 [Source:HGNC Symbol;Acc:HGNC:27800] | 11892 | 0.000 | 0.3955 | No |
| 59 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12266 | 0.000 | 0.3854 | No |
| 60 | LILRA5 | leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309] | 13275 | 0.000 | 0.3581 | No |
| 61 | LILRB1 | leukocyte immunoglobulin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6605] | 13279 | 0.000 | 0.3581 | No |
| 62 | LILRB2 | leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606] | 13280 | 0.000 | 0.3581 | No |
| 63 | LILRB3 | leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607] | 13281 | 0.000 | 0.3581 | No |
| 64 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13282 | 0.000 | 0.3581 | No |
| 65 | LILRB5 | leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609] | 13283 | 0.000 | 0.3581 | No |
| 66 | MEGF11 | multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635] | 14202 | 0.000 | 0.3332 | No |
| 67 | EBI3 | Epstein-Barr virus induced 3 [Source:HGNC Symbol;Acc:HGNC:3129] | 14912 | 0.000 | 0.3140 | No |
| 68 | GHRL | ghrelin and obestatin prepropeptide [Source:HGNC Symbol;Acc:HGNC:18129] | 15029 | 0.000 | 0.3109 | No |
| 69 | CD300LF | CD300 molecule like family member f [Source:HGNC Symbol;Acc:HGNC:29883] | 15744 | 0.000 | 0.2916 | No |
| 70 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15801 | 0.000 | 0.2901 | No |
| 71 | NEXMIF | neurite extension and migration factor [Source:HGNC Symbol;Acc:HGNC:29433] | 15972 | 0.000 | 0.2855 | No |
| 72 | TIMD4 | T cell immunoglobulin and mucin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25132] | 16172 | 0.000 | 0.2801 | No |
| 73 | TMEM63C | transmembrane protein 63C [Source:HGNC Symbol;Acc:HGNC:23787] | 18266 | 0.000 | 0.2235 | No |
| 74 | RN7SL138P | RNA, 7SL, cytoplasmic 138, pseudogene [Source:HGNC Symbol;Acc:HGNC:46154] | 18383 | 0.000 | 0.2203 | No |
| 75 | MRO | maestro [Source:HGNC Symbol;Acc:HGNC:24121] | 19070 | 0.000 | 0.2018 | No |
| 76 | MERTK | MER proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7027] | 20499 | 0.000 | 0.1631 | No |
| 77 | CD163L1 | CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375] | 20891 | 0.000 | 0.1526 | No |
| 78 | SIGLEC7 | sialic acid binding Ig like lectin 7 [Source:HGNC Symbol;Acc:HGNC:10876] | 21054 | 0.000 | 0.1482 | No |
| 79 | NRIR | negative regulator of interferon response [Source:HGNC Symbol;Acc:HGNC:51269] | 21121 | 0.000 | 0.1464 | No |
| 80 | ADGRE2 | adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337] | 21307 | 0.000 | 0.1414 | No |
| 81 | EYA2 | EYA transcriptional coactivator and phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3520] | 21363 | 0.000 | 0.1399 | No |
| 82 | NCKAP5 | NCK associated protein 5 [Source:HGNC Symbol;Acc:HGNC:29847] | 21377 | 0.000 | 0.1395 | No |
| 83 | CABP4 | calcium binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1386] | 21735 | 0.000 | 0.1299 | No |
| 84 | KCNMA1 | potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284] | 21878 | 0.000 | 0.1260 | No |
| 85 | PDCD1LG2 | programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] | 22625 | 0.000 | 0.1059 | No |
| 86 | CCDC170 | coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177] | 23081 | 0.000 | 0.0936 | No |
| 87 | MS4A4E | membrane spanning 4-domains A4E [Source:HGNC Symbol;Acc:HGNC:14284] | 23127 | 0.000 | 0.0923 | No |
| 88 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 23133 | 0.000 | 0.0922 | No |
| 89 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 23140 | 0.000 | 0.0920 | No |
| 90 | SPIC | Spi-C transcription factor [Source:HGNC Symbol;Acc:HGNC:29549] | 23442 | 0.000 | 0.0839 | No |
| 91 | ZNF415P1 | zinc finger protein 415 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49869] | 23509 | 0.000 | 0.0821 | No |
| 92 | HRH1 | histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] | 23903 | 0.000 | 0.0715 | No |
| 93 | OSCAR | osteoclast associated Ig-like receptor [Source:HGNC Symbol;Acc:HGNC:29960] | 24184 | 0.000 | 0.0639 | No |
| 94 | SIRPB2 | signal regulatory protein beta 2 [Source:HGNC Symbol;Acc:HGNC:16247] | 24202 | 0.000 | 0.0634 | No |
| 95 | DSCAM | DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039] | 24614 | 0.000 | 0.0523 | No |
| 96 | RUFY4 | RUN and FYVE domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24804] | 24876 | 0.000 | 0.0453 | No |
| 97 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 24881 | 0.000 | 0.0452 | No |
| 98 | CMKLR1 | chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121] | 27260 | 0.000 | -0.0192 | No |
| 99 | DSCAM-IT1 | DSCAM intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41327] | 27543 | 0.000 | -0.0268 | No |
| 100 | CLEC9A | C-type lectin domain containing 9A [Source:HGNC Symbol;Acc:HGNC:26705] | 27921 | 0.000 | -0.0370 | No |
| 101 | RAB39A | RAB39A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16521] | 29041 | -0.244 | -0.0654 | No |
| 102 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 29072 | -0.244 | -0.0644 | No |
| 103 | HK3 | hexokinase 3 [Source:HGNC Symbol;Acc:HGNC:4925] | 29099 | -0.253 | -0.0632 | No |
| 104 | TRPV4 | transient receptor potential cation channel subfamily V member 4 [Source:HGNC Symbol;Acc:HGNC:18083] | 29422 | -0.346 | -0.0693 | No |
| 105 | RGL3 | ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282] | 29570 | -0.378 | -0.0704 | No |
| 106 | TRIM36 | tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280] | 30129 | -0.534 | -0.0814 | No |
| 107 | PPARG | peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] | 30143 | -0.537 | -0.0777 | No |
| 108 | FMN1 | formin 1 [Source:HGNC Symbol;Acc:HGNC:3768] | 30417 | -0.589 | -0.0806 | No |
| 109 | IGSF6 | immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953] | 30553 | -0.637 | -0.0795 | No |
| 110 | CD200R1 | CD200 receptor 1 [Source:HGNC Symbol;Acc:HGNC:24235] | 30587 | -0.647 | -0.0755 | No |
| 111 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 31239 | -0.842 | -0.0867 | No |
| 112 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase [Source:HGNC Symbol;Acc:HGNC:23015] | 31747 | -1.006 | -0.0928 | No |
| 113 | DMXL2 | Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938] | 32065 | -1.119 | -0.0929 | No |
| 114 | MKNK1 | MAPK interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110] | 32068 | -1.121 | -0.0845 | No |
| 115 | LRRK1 | leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608] | 32186 | -1.170 | -0.0788 | No |
| 116 | CDS1 | CDP-diacylglycerol synthase 1 [Source:HGNC Symbol;Acc:HGNC:1800] | 32468 | -1.232 | -0.0770 | No |
| 117 | MCOLN1 | mucolipin 1 [Source:HGNC Symbol;Acc:HGNC:13356] | 32868 | -1.381 | -0.0774 | No |
| 118 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 33225 | -1.544 | -0.0753 | No |
| 119 | ZNF710 | zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352] | 34245 | -2.051 | -0.0874 | No |
| 120 | KCNK13 | potassium two pore domain channel subfamily K member 13 [Source:HGNC Symbol;Acc:HGNC:6275] | 34731 | -2.307 | -0.0830 | No |
| 121 | SIRPB1 | signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928] | 34738 | -2.310 | -0.0657 | No |
| 122 | ALMS1P1 | ALMS1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:29586] | 35158 | -2.606 | -0.0573 | No |
| 123 | WWP1 | WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:17004] | 35843 | -3.179 | -0.0517 | No |
| 124 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 36139 | -3.470 | -0.0334 | No |
| 125 | SLC8A1 | solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068] | 36441 | -3.802 | -0.0128 | No |
| 126 | FLVCR2 | FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105] | 36594 | -4.003 | 0.0134 | No |
