Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | HALLMARK_NOTCH_SIGNALING |
| Enrichment Score (ES) | 0.3812681 |
| Normalized Enrichment Score (NES) | 0.8106429 |
| Nominal p-value | 0.8553719 |
| FDR q-value | 0.95806015 |
| FWER p-Value | 0.989 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NOTCH1 | notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881] | 118 | 4.535 | 0.0982 | Yes |
| 2 | DLL1 | delta like canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:2908] | 161 | 4.301 | 0.1932 | Yes |
| 3 | FZD5 | frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043] | 388 | 3.517 | 0.2657 | Yes |
| 4 | DTX2 | deltex E3 ubiquitin ligase 2 [Source:HGNC Symbol;Acc:HGNC:15973] | 1159 | 2.086 | 0.2915 | Yes |
| 5 | DTX1 | deltex E3 ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:3060] | 1244 | 2.075 | 0.3356 | Yes |
| 6 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 1271 | 2.073 | 0.3813 | Yes |
| 7 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 3385 | 0.725 | 0.3405 | No |
| 8 | DTX4 | deltex E3 ubiquitin ligase 4 [Source:HGNC Symbol;Acc:HGNC:29151] | 3784 | 0.567 | 0.3424 | No |
| 9 | APH1A | aph-1 homolog A, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:29509] | 4002 | 0.488 | 0.3474 | No |
| 10 | PSENEN | presenilin enhancer, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:30100] | 4773 | 0.356 | 0.3346 | No |
| 11 | FBXW11 | F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:HGNC:13607] | 4833 | 0.338 | 0.3406 | No |
| 12 | NOTCH2 | notch receptor 2 [Source:HGNC Symbol;Acc:HGNC:7882] | 5041 | 0.263 | 0.3409 | No |
| 13 | SKP1 | S-phase kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:10899] | 5068 | 0.254 | 0.3458 | No |
| 14 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 6869 | 0.000 | 0.2972 | No |
| 15 | HEYL | hes related family bHLH transcription factor with YRPW motif like [Source:HGNC Symbol;Acc:HGNC:4882] | 7017 | 0.000 | 0.2933 | No |
| 16 | FZD1 | frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038] | 19230 | 0.000 | -0.0362 | No |
| 17 | WNT5A | Wnt family member 5A [Source:HGNC Symbol;Acc:HGNC:12784] | 21710 | 0.000 | -0.1031 | No |
| 18 | WNT2 | Wnt family member 2 [Source:HGNC Symbol;Acc:HGNC:12780] | 22098 | 0.000 | -0.1136 | No |
| 19 | NOTCH3 | notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883] | 24368 | 0.000 | -0.1748 | No |
| 20 | RBX1 | ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928] | 28206 | -0.025 | -0.2778 | No |
| 21 | CUL1 | cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551] | 29850 | -0.456 | -0.3119 | No |
| 22 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 29996 | -0.499 | -0.3047 | No |
| 23 | ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080] | 30292 | -0.552 | -0.3003 | No |
| 24 | TCF7L2 | transcription factor 7 like 2 [Source:HGNC Symbol;Acc:HGNC:11641] | 31359 | -0.878 | -0.3095 | No |
| 25 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 31434 | -0.906 | -0.2912 | No |
| 26 | PSEN2 | presenilin 2 [Source:HGNC Symbol;Acc:HGNC:9509] | 31689 | -0.987 | -0.2760 | No |
| 27 | PRKCA | protein kinase C alpha [Source:HGNC Symbol;Acc:HGNC:9393] | 33260 | -1.559 | -0.2835 | No |
| 28 | KAT2A | lysine acetyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:4201] | 33697 | -1.751 | -0.2562 | No |
| 29 | CCND1 | cyclin D1 [Source:HGNC Symbol;Acc:HGNC:1582] | 34510 | -2.164 | -0.2297 | No |
| 30 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 36520 | -3.908 | -0.1965 | No |
| 31 | FZD7 | frizzled class receptor 7 [Source:HGNC Symbol;Acc:HGNC:4045] | 36953 | -4.567 | -0.1061 | No |
| 32 | ARRB1 | arrestin beta 1 [Source:HGNC Symbol;Acc:HGNC:711] | 37058 | -4.912 | 0.0009 | No |
