Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HALLMARK_PEROXISOME |
| Enrichment Score (ES) | -0.6020022 |
| Normalized Enrichment Score (NES) | -1.2646595 |
| Nominal p-value | 0.05479452 |
| FDR q-value | 0.18185508 |
| FWER p-Value | 0.89 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433] | 330 | 3.693 | 0.0157 | No |
| 2 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 427 | 3.359 | 0.0356 | No |
| 3 | ATXN1 | ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548] | 523 | 3.168 | 0.0541 | No |
| 4 | PRDX5 | peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355] | 889 | 2.512 | 0.0610 | No |
| 5 | PEX11A | peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852] | 985 | 2.347 | 0.0741 | No |
| 6 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 1055 | 2.227 | 0.0871 | No |
| 7 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1470 | 1.842 | 0.0882 | No |
| 8 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 1626 | 1.695 | 0.0954 | No |
| 9 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 1893 | 1.470 | 0.0980 | No |
| 10 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 1920 | 1.455 | 0.1070 | No |
| 11 | SLC25A19 | solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409] | 1928 | 1.449 | 0.1165 | No |
| 12 | CNBP | CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164] | 2732 | 1.012 | 0.1015 | No |
| 13 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 2736 | 1.010 | 0.1082 | No |
| 14 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 3053 | 0.854 | 0.1054 | No |
| 15 | VPS4B | vacuolar protein sorting 4 homolog B [Source:HGNC Symbol;Acc:HGNC:10895] | 3258 | 0.775 | 0.1050 | No |
| 16 | YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853] | 3314 | 0.757 | 0.1086 | No |
| 17 | CDK7 | cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778] | 3486 | 0.688 | 0.1086 | No |
| 18 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 4412 | 0.468 | 0.0867 | No |
| 19 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 4600 | 0.407 | 0.0843 | No |
| 20 | ISOC1 | isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] | 4651 | 0.391 | 0.0856 | No |
| 21 | PABPC1 | poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554] | 5533 | 0.126 | 0.0626 | No |
| 22 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 5754 | 0.064 | 0.0571 | No |
| 23 | EPHX2 | epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] | 7622 | 0.000 | 0.0066 | No |
| 24 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 7639 | 0.000 | 0.0062 | No |
| 25 | GSTK1 | glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906] | 9366 | 0.000 | -0.0405 | No |
| 26 | ESR2 | estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468] | 11750 | 0.000 | -0.1049 | No |
| 27 | STS | steroid sulfatase [Source:HGNC Symbol;Acc:HGNC:11425] | 12253 | 0.000 | -0.1185 | No |
| 28 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12521 | 0.000 | -0.1257 | No |
| 29 | HSD11B2 | hydroxysteroid 11-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5209] | 14274 | 0.000 | -0.1731 | No |
| 30 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15668 | 0.000 | -0.2107 | No |
| 31 | DIO1 | iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883] | 15731 | 0.000 | -0.2124 | No |
| 32 | SERPINA6 | serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540] | 17774 | 0.000 | -0.2676 | No |
| 33 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 17847 | 0.000 | -0.2696 | No |
| 34 | UGT2B17 | UDP glucuronosyltransferase family 2 member B17 [Source:HGNC Symbol;Acc:HGNC:12547] | 18182 | 0.000 | -0.2786 | No |
| 35 | NR1I2 | nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968] | 20003 | 0.000 | -0.3278 | No |
| 36 | SULT2B1 | sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459] | 20655 | 0.000 | -0.3454 | No |
| 37 | CRABP2 | cellular retinoic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2339] | 20944 | 0.000 | -0.3532 | No |
| 38 | CRABP1 | cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338] | 20945 | 0.000 | -0.3532 | No |
| 39 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 21142 | 0.000 | -0.3585 | No |
| 40 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 21850 | 0.000 | -0.3776 | No |
| 41 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 22737 | 0.000 | -0.4016 | No |
| 42 | FABP6 | fatty acid binding protein 6 [Source:HGNC Symbol;Acc:HGNC:3561] | 23995 | 0.000 | -0.4355 | No |
| 43 | ALB | albumin [Source:HGNC Symbol;Acc:HGNC:399] | 24416 | 0.000 | -0.4469 | No |
| 44 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 28088 | 0.000 | -0.5461 | No |
| 45 | PEX5 | peroxisomal biogenesis factor 5 [Source:HGNC Symbol;Acc:HGNC:9719] | 28145 | -0.009 | -0.5476 | No |
| 46 | PEX14 | peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856] | 28167 | -0.014 | -0.5481 | No |
| 47 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 28308 | -0.057 | -0.5515 | No |
| 48 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 28388 | -0.081 | -0.5531 | No |
| 49 | SIAH1 | siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857] | 28493 | -0.102 | -0.5552 | No |
| 50 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 28972 | -0.229 | -0.5666 | No |
| 51 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29239 | -0.295 | -0.5718 | No |
| 52 | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3435] | 29592 | -0.385 | -0.5788 | No |
| 53 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 29796 | -0.441 | -0.5813 | No |
| 54 | CTBP1 | C-terminal binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2494] | 30311 | -0.558 | -0.5915 | No |
| 55 | SLC23A2 | solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973] | 30315 | -0.560 | -0.5878 | No |
| 56 | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [Source:HGNC Symbol;Acc:HGNC:11104] | 30834 | -0.721 | -0.5970 | Yes |
| 57 | FIS1 | fission, mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:21689] | 30990 | -0.765 | -0.5961 | Yes |
| 58 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 31179 | -0.818 | -0.5957 | Yes |
| 59 | RDH11 | retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] | 31314 | -0.865 | -0.5936 | Yes |
| 60 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 31627 | -0.966 | -0.5956 | Yes |
| 61 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 31636 | -0.969 | -0.5893 | Yes |
| 62 | HRAS | HRas proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:5173] | 31742 | -1.005 | -0.5854 | Yes |
| 63 | ACSL1 | acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] | 31786 | -1.020 | -0.5798 | Yes |
| 64 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 31998 | -1.092 | -0.5782 | Yes |
| 65 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 32216 | -1.184 | -0.5762 | Yes |
| 66 | ACSL5 | acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526] | 32288 | -1.215 | -0.5700 | Yes |
| 67 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 33424 | -1.630 | -0.5898 | Yes |
| 68 | HMGCL | 3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005] | 33730 | -1.766 | -0.5862 | Yes |
| 69 | ABCB9 | ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50] | 33736 | -1.771 | -0.5745 | Yes |
| 70 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 33829 | -1.826 | -0.5648 | Yes |
| 71 | RXRG | retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] | 33936 | -1.880 | -0.5551 | Yes |
| 72 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 34018 | -1.925 | -0.5445 | Yes |
| 73 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 34028 | -1.929 | -0.5318 | Yes |
| 74 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 34167 | -2.006 | -0.5222 | Yes |
| 75 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34305 | -2.081 | -0.5120 | Yes |
| 76 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 34462 | -2.130 | -0.5020 | Yes |
| 77 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 34690 | -2.286 | -0.4929 | Yes |
| 78 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 34707 | -2.292 | -0.4780 | Yes |
| 79 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 34902 | -2.428 | -0.4670 | Yes |
| 80 | CACNA1B | calcium voltage-gated channel subunit alpha1 B [Source:HGNC Symbol;Acc:HGNC:1389] | 34931 | -2.432 | -0.4516 | Yes |
| 81 | CADM1 | cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951] | 34967 | -2.459 | -0.4361 | Yes |
| 82 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 34969 | -2.461 | -0.4197 | Yes |
| 83 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 34973 | -2.463 | -0.4033 | Yes |
| 84 | RETSAT | retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991] | 35106 | -2.563 | -0.3898 | Yes |
| 85 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35119 | -2.573 | -0.3729 | Yes |
| 86 | DLG4 | discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903] | 35162 | -2.609 | -0.3566 | Yes |
| 87 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 35196 | -2.643 | -0.3399 | Yes |
| 88 | ABCC5 | ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56] | 35217 | -2.663 | -0.3226 | Yes |
| 89 | HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324] | 35236 | -2.675 | -0.3053 | Yes |
| 90 | GNPAT | glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416] | 35335 | -2.708 | -0.2898 | Yes |
| 91 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 35422 | -2.773 | -0.2737 | Yes |
| 92 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35624 | -2.974 | -0.2592 | Yes |
| 93 | ALDH9A1 | aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] | 35743 | -3.081 | -0.2419 | Yes |
| 94 | ABCB4 | ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] | 35781 | -3.121 | -0.2220 | Yes |
| 95 | ELOVL5 | ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] | 35877 | -3.225 | -0.2031 | Yes |
| 96 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36054 | -3.383 | -0.1852 | Yes |
| 97 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36100 | -3.438 | -0.1635 | Yes |
| 98 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36319 | -3.655 | -0.1450 | Yes |
| 99 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 36470 | -3.832 | -0.1235 | Yes |
| 100 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382] | 36479 | -3.842 | -0.0980 | Yes |
| 101 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36637 | -4.046 | -0.0753 | Yes |
| 102 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36821 | -4.303 | -0.0515 | Yes |
| 103 | DHCR24 | 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] | 36824 | -4.316 | -0.0227 | Yes |
| 104 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 36913 | -4.479 | 0.0048 | Yes |
