Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.37371516 |
| Normalized Enrichment Score (NES) | 0.8356173 |
| Nominal p-value | 0.8511628 |
| FDR q-value | 0.9886503 |
| FWER p-Value | 0.989 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 265 | 3.877 | 0.0550 | Yes |
| 2 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 377 | 3.549 | 0.1090 | Yes |
| 3 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 427 | 3.359 | 0.1615 | Yes |
| 4 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 716 | 2.835 | 0.1992 | Yes |
| 5 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 942 | 2.417 | 0.2319 | Yes |
| 6 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 981 | 2.354 | 0.2686 | Yes |
| 7 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1470 | 1.842 | 0.2850 | Yes |
| 8 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 1757 | 1.579 | 0.3026 | Yes |
| 9 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1865 | 1.496 | 0.3237 | Yes |
| 10 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 2153 | 1.328 | 0.3373 | Yes |
| 11 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 2279 | 1.259 | 0.3541 | Yes |
| 12 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 3158 | 0.812 | 0.3434 | Yes |
| 13 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 3274 | 0.769 | 0.3526 | Yes |
| 14 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 3352 | 0.740 | 0.3624 | Yes |
| 15 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 3370 | 0.732 | 0.3737 | Yes |
| 16 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 3762 | 0.576 | 0.3724 | No |
| 17 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 4859 | 0.329 | 0.3481 | No |
| 18 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 5089 | 0.247 | 0.3459 | No |
| 19 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 5421 | 0.151 | 0.3394 | No |
| 20 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 5550 | 0.122 | 0.3379 | No |
| 21 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 5833 | 0.037 | 0.3308 | No |
| 22 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9195 | 0.000 | 0.2401 | No |
| 23 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 11647 | 0.000 | 0.1739 | No |
| 24 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 17726 | 0.000 | 0.0099 | No |
| 25 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17916 | 0.000 | 0.0048 | No |
| 26 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19047 | 0.000 | -0.0257 | No |
| 27 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 27807 | 0.000 | -0.2622 | No |
| 28 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 28243 | -0.037 | -0.2734 | No |
| 29 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29239 | -0.295 | -0.2955 | No |
| 30 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 29350 | -0.327 | -0.2932 | No |
| 31 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 29781 | -0.436 | -0.2978 | No |
| 32 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 30282 | -0.549 | -0.3025 | No |
| 33 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 30286 | -0.551 | -0.2938 | No |
| 34 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 30744 | -0.696 | -0.2949 | No |
| 35 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31333 | -0.870 | -0.2969 | No |
| 36 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 31893 | -1.055 | -0.2950 | No |
| 37 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 31975 | -1.084 | -0.2798 | No |
| 38 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 31984 | -1.087 | -0.2626 | No |
| 39 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 32699 | -1.320 | -0.2607 | No |
| 40 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 32799 | -1.358 | -0.2416 | No |
| 41 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 32948 | -1.423 | -0.2228 | No |
| 42 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 33209 | -1.539 | -0.2051 | No |
| 43 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 33268 | -1.561 | -0.1816 | No |
| 44 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 33436 | -1.635 | -0.1599 | No |
| 45 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35119 | -2.573 | -0.1641 | No |
| 46 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 35785 | -3.126 | -0.1319 | No |
| 47 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35818 | -3.164 | -0.0820 | No |
| 48 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 36275 | -3.604 | -0.0365 | No |
| 49 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36315 | -3.646 | 0.0209 | No |
