Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HALLMARK_SPERMATOGENESIS |
| Enrichment Score (ES) | -0.6234215 |
| Normalized Enrichment Score (NES) | -1.3309257 |
| Nominal p-value | 0.014238773 |
| FDR q-value | 0.15224479 |
| FWER p-Value | 0.578 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MLF1 | myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125] | 376 | 3.551 | 0.0171 | No |
| 2 | PACRG | parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152] | 545 | 3.128 | 0.0365 | No |
| 3 | ELOVL3 | ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047] | 710 | 2.839 | 0.0539 | No |
| 4 | TEKT2 | tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725] | 761 | 2.723 | 0.0734 | No |
| 5 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 914 | 2.461 | 0.0882 | No |
| 6 | DPEP3 | dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029] | 2028 | 1.411 | 0.0689 | No |
| 7 | ARL4A | ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695] | 2342 | 1.223 | 0.0698 | No |
| 8 | STAM2 | signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358] | 2636 | 1.057 | 0.0700 | No |
| 9 | TLE4 | TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840] | 2817 | 0.967 | 0.0725 | No |
| 10 | AGFG1 | ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] | 3602 | 0.640 | 0.0562 | No |
| 11 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 3850 | 0.543 | 0.0537 | No |
| 12 | PAPOLB | poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970] | 3909 | 0.519 | 0.0561 | No |
| 13 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 4025 | 0.478 | 0.0566 | No |
| 14 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 4417 | 0.466 | 0.0496 | No |
| 15 | PGS1 | phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029] | 4898 | 0.316 | 0.0391 | No |
| 16 | HSPA1L | heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234] | 5174 | 0.221 | 0.0333 | No |
| 17 | CSNK2A2 | casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459] | 5250 | 0.203 | 0.0329 | No |
| 18 | PIAS2 | protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311] | 5306 | 0.184 | 0.0328 | No |
| 19 | NAA11 | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] | 5616 | 0.106 | 0.0252 | No |
| 20 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6180 | 0.000 | 0.0100 | No |
| 21 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6182 | 0.000 | 0.0100 | No |
| 22 | ADCYAP1 | adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241] | 7027 | 0.000 | -0.0129 | No |
| 23 | ART3 | ADP-ribosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:725] | 7136 | 0.000 | -0.0158 | No |
| 24 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7241 | 0.000 | -0.0186 | No |
| 25 | ZC2HC1C | zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354] | 7958 | 0.000 | -0.0380 | No |
| 26 | HOXB1 | homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111] | 8529 | 0.000 | -0.0534 | No |
| 27 | ADAM2 | ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198] | 8609 | 0.000 | -0.0555 | No |
| 28 | ADAD1 | adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713] | 8763 | 0.000 | -0.0597 | No |
| 29 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 8785 | 0.000 | -0.0602 | No |
| 30 | CRISP2 | cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024] | 8827 | 0.000 | -0.0614 | No |
| 31 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 8834 | 0.000 | -0.0615 | No |
| 32 | DMRT1 | doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934] | 9283 | 0.000 | -0.0736 | No |
| 33 | NEFH | neurofilament heavy [Source:HGNC Symbol;Acc:HGNC:7737] | 9400 | 0.000 | -0.0768 | No |
| 34 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9693 | 0.000 | -0.0847 | No |
| 35 | TULP2 | TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424] | 9868 | 0.000 | -0.0894 | No |
| 36 | CFTR | CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884] | 9904 | 0.000 | -0.0903 | No |
| 37 | LDHC | lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544] | 10879 | 0.000 | -0.1167 | No |
| 38 | CLGN | calmegin [Source:HGNC Symbol;Acc:HGNC:2060] | 11350 | 0.000 | -0.1294 | No |
| 39 | PRM2 | protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448] | 11356 | 0.000 | -0.1295 | No |
| 40 | SEPTIN4 | septin 4 [Source:HGNC Symbol;Acc:HGNC:9165] | 11536 | 0.000 | -0.1344 | No |
| 41 | RPL39L | ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094] | 11656 | 0.000 | -0.1376 | No |
| 42 | JAM3 | junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532] | 11898 | 0.000 | -0.1441 | No |
| 43 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 12323 | 0.000 | -0.1556 | No |
| 44 | THEG | theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706] | 12541 | 0.000 | -0.1615 | No |
| 45 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 12612 | 0.000 | -0.1634 | No |
| 46 | TCP11 | t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658] | 14331 | 0.000 | -0.2099 | No |
| 47 | TNP2 | transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952] | 14865 | 0.000 | -0.2243 | No |
| 48 | TNP1 | transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951] | 14867 | 0.000 | -0.2243 | No |
| 49 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15522 | 0.000 | -0.2420 | No |
| 50 | CLVS1 | clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139] | 15648 | 0.000 | -0.2454 | No |
| 51 | MTNR1A | melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463] | 15734 | 0.000 | -0.2477 | No |
| 52 | DCC | DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701] | 15932 | 0.000 | -0.2530 | No |
| 53 | ACTL7B | actin like 7B [Source:HGNC Symbol;Acc:HGNC:162] | 16012 | 0.000 | -0.2552 | No |
| 54 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 16320 | 0.000 | -0.2635 | No |
| 55 | GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864] | 16428 | 0.000 | -0.2664 | No |
| 56 | AKAP4 | A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374] | 16586 | 0.000 | -0.2706 | No |
| 57 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16854 | 0.000 | -0.2778 | No |
| 58 | TKTL1 | transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835] | 17190 | 0.000 | -0.2869 | No |
| 59 | HBZ | hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835] | 17237 | 0.000 | -0.2881 | No |
| 60 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17841 | 0.000 | -0.3045 | No |
| 61 | DNAJB8 | DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699] | 18519 | 0.000 | -0.3228 | No |
| 62 | IL12RB2 | interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] | 19662 | 0.000 | -0.3537 | No |
| 63 | MEP1B | meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020] | 20124 | 0.000 | -0.3661 | No |
| 64 | ACRV1 | acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127] | 20331 | 0.000 | -0.3717 | No |
| 65 | TSSK2 | testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401] | 21495 | 0.000 | -0.4032 | No |
| 66 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 21630 | 0.000 | -0.4068 | No |
| 67 | CST8 | cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480] | 21668 | 0.000 | -0.4078 | No |
| 68 | OAZ3 | ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097] | 22786 | 0.000 | -0.4380 | No |
| 69 | ODF1 | outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113] | 23512 | 0.000 | -0.4577 | No |
| 70 | ZNRF4 | zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726] | 23553 | 0.000 | -0.4587 | No |
| 71 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 24249 | 0.000 | -0.4776 | No |
| 72 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 24546 | 0.000 | -0.4856 | No |
| 73 | SLC2A5 | solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010] | 24630 | 0.000 | -0.4878 | No |
| 74 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 25494 | 0.000 | -0.5112 | No |
| 75 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 25621 | 0.000 | -0.5146 | No |
| 76 | H1-6 | H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720] | 27669 | 0.000 | -0.5700 | No |
| 77 | DDX25 | DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698] | 28047 | 0.000 | -0.5802 | No |
| 78 | IP6K1 | inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360] | 28349 | -0.066 | -0.5878 | No |
| 79 | TSN | translin [Source:HGNC Symbol;Acc:HGNC:12379] | 28522 | -0.109 | -0.5916 | No |
| 80 | YBX2 | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] | 28763 | -0.173 | -0.5968 | No |
| 81 | TALDO1 | transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559] | 29213 | -0.288 | -0.6067 | No |
| 82 | CLPB | caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664] | 29588 | -0.383 | -0.6139 | No |
| 83 | CHFR | checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455] | 29605 | -0.389 | -0.6114 | No |
| 84 | PEBP1 | phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630] | 29669 | -0.408 | -0.6099 | No |
| 85 | PDHA2 | pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807] | 29758 | -0.431 | -0.6090 | No |
| 86 | PHKG2 | phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931] | 29769 | -0.435 | -0.6059 | No |
| 87 | PSMG1 | proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043] | 30116 | -0.531 | -0.6112 | No |
| 88 | VDAC3 | voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674] | 30433 | -0.596 | -0.6152 | No |
| 89 | SIRT1 | sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929] | 30622 | -0.658 | -0.6152 | No |
| 90 | ZPBP | zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662] | 30925 | -0.745 | -0.6177 | Yes |
| 91 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 31053 | -0.790 | -0.6151 | Yes |
| 92 | BRAF | B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097] | 31128 | -0.801 | -0.6109 | Yes |
| 93 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 31224 | -0.836 | -0.6071 | Yes |
| 94 | TUBA3C | tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408] | 31282 | -0.856 | -0.6021 | Yes |
| 95 | NOS1 | nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872] | 31510 | -0.920 | -0.6012 | Yes |
| 96 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063] | 32013 | -1.097 | -0.6063 | Yes |
| 97 | COIL | coilin [Source:HGNC Symbol;Acc:HGNC:2184] | 32046 | -1.111 | -0.5987 | Yes |
| 98 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 32154 | -1.159 | -0.5927 | Yes |
| 99 | GSTM3 | glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635] | 32299 | -1.222 | -0.5872 | Yes |
| 100 | ACRBP | acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195] | 32682 | -1.312 | -0.5875 | Yes |
| 101 | GSG1 | germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716] | 32848 | -1.374 | -0.5814 | Yes |
| 102 | ZC3H14 | zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509] | 33186 | -1.524 | -0.5788 | Yes |
| 103 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33303 | -1.578 | -0.5699 | Yes |
| 104 | PGK2 | phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898] | 33425 | -1.630 | -0.5606 | Yes |
| 105 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391] | 33433 | -1.634 | -0.5483 | Yes |
| 106 | IFT88 | intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606] | 33513 | -1.669 | -0.5376 | Yes |
| 107 | NF2 | neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773] | 33587 | -1.713 | -0.5264 | Yes |
| 108 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 33605 | -1.725 | -0.5137 | Yes |
| 109 | POMC | proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201] | 33675 | -1.740 | -0.5022 | Yes |
| 110 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 33921 | -1.879 | -0.4944 | Yes |
| 111 | PHF7 | PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458] | 33989 | -1.907 | -0.4816 | Yes |
| 112 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 33994 | -1.910 | -0.4670 | Yes |
| 113 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 34028 | -1.929 | -0.4531 | Yes |
| 114 | HSPA4L | heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041] | 34218 | -2.035 | -0.4426 | Yes |
| 115 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 34324 | -2.099 | -0.4294 | Yes |
| 116 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 34396 | -2.127 | -0.4150 | Yes |
| 117 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 34718 | -2.299 | -0.4060 | Yes |
| 118 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 34837 | -2.379 | -0.3910 | Yes |
| 119 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 34861 | -2.396 | -0.3732 | Yes |
| 120 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35172 | -2.617 | -0.3615 | Yes |
| 121 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35361 | -2.726 | -0.3457 | Yes |
| 122 | STRBP | spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462] | 35527 | -2.874 | -0.3281 | Yes |
| 123 | MAST2 | microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035] | 35616 | -2.966 | -0.3077 | Yes |
| 124 | TNNI3 | troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947] | 35674 | -3.047 | -0.2859 | Yes |
| 125 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 35831 | -3.171 | -0.2658 | Yes |
| 126 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 36154 | -3.490 | -0.2477 | Yes |
| 127 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36172 | -3.498 | -0.2213 | Yes |
| 128 | PCSK4 | proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746] | 36177 | -3.510 | -0.1945 | Yes |
| 129 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36388 | -3.732 | -0.1716 | Yes |
| 130 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36393 | -3.744 | -0.1430 | Yes |
| 131 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36508 | -3.891 | -0.1162 | Yes |
| 132 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36519 | -3.907 | -0.0865 | Yes |
| 133 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36709 | -4.137 | -0.0599 | Yes |
| 134 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36941 | -4.548 | -0.0312 | Yes |
| 135 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 36962 | -4.592 | 0.0035 | Yes |
